Clinical trials: Colonoscopy Procedure
Post-polypectomy Bleeding, Polypectomy
Risk of Post-polypectomy Bleeding With Prophylactic Hemoclipping
A randomized trial aimed at determining whether or not hemoclips are effective in preventing post-polypectomy bleeds on polyps that are 10mm in size or greater.
- Conditions
- Post-polypectomy Bleeding, Polypectomy, Elective Colonoscopy
- Trial name
- NCT01647581
- Testing
- Hemoclip Placement, NO hemoclip placement
- Where
- 3 sites in United States
- Volunteers
- 11,182 people
- Sponsor
- VA Office of Research and Development
Colonoscopy
A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
The objective of this study is to compare the safety, tolerance and efficacy of BLI800 to a PEG based preparation prior to colonoscopy in adolescent patients.
- Trial name
- NCT02819323
- Testing
- PEG-ELS, BLI800
- Where
- 27 sites in United States
- Volunteers
- 91 people
- Sponsor
- Braintree Laboratories
Colonic Adenoma, Water Exchange Colonoscopy
Adenoma Miss Rate With Water Exchange vs Carbon Dioxide Colonoscopy
This was an observational study comparing consecutive group of WE and CO2 insufflation in terms of right and proximal colon AMR by tandem colonoscopy.
- Trial name
- NCT03832322
- Testing
- Water exchange colonoscopy, CO2 insufflation colonoscopy
- Where
- Taiwan
- Volunteers
- 176 people
- Sponsor
- Evergreen General Hospital, Taiwan
Hypoxia, Apnea
Use of Capnography in EGD and Colonoscopy With Moderate Sedation.
This study will provide capnography monitoring during routine upper endoscopy and colonoscopy with moderate sedation in order to see if it improves safety.
- Conditions
- Hypoxia, Apnea, Hypotension, Hypopnea
- Trial name
- NCT01994785
- Testing
- Capnographic Monitoring
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- The Cleveland Clinic
Colonoscopy, Bowel Preparation
A Safety Study of 3 Different Bowel Cleansing Preparations
The objective of this study is to compare the safety, tolerance and efficacy of BLI800 (approved and investigational regimens) to an approved control preparation as bowel preparations prior to colonoscopy in adult patients…
- Conditions
- Colonoscopy, Bowel Preparation, Endoscopy
- Trial name
- NCT01501513
- Testing
- PEG-3350 based bowel preparation, BLI800 approved preparation regimen, BLI800 investigational preparation regimen
- Where
- 17 sites in United States
- Volunteers
- 541 people
- Sponsor
- Braintree Laboratories
Colonoscopy
A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in patients undergoing a colonoscopy…
- Trial name
- NCT02290873
- Testing
- Remimazolam, Midazolam
- Where
- 13 sites in United States
- Volunteers
- 461 people
- Sponsor
- Paion UK Ltd.
Bowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel.
Evaluation of the Efficacy, Safety and Tolerance of Experimental Morning-only MOVIPREP® Bowel Preparation in Comparison With Split-dose With Nocturnal Pause MOVIPREP® Bowel Preparation
To compare colon cleansing quality induced by the 2 different modes of MOVIPREP® intake in 5 colon segments prior to colonoscopy.
- Trial name
- NCT01732692
- Testing
- MOVIPREP
- Where
- 3 sites in Kazakhstan, Russia
- Volunteers
- 140 people
- Sponsor
- Takeda
Colorectal Cancer
Colonoscopy Outreach for Rural Communities Aim 2
This study aims to test the effectiveness of a remotely-delivered patient navigation program for increasing colonoscopy completion for colorectal cancer screening, among rural populations.
- Trial name
- NCT05453630
- Testing
- Patient Navigation, Usual Care Control
- Where
- United States
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- University of Washington
Spinal Cord Injury
Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
The annual incidence of colorectal cancer in the US during 2005 was approximately 150,000 cases and this neoplasm claimed 56,000 lives (American Cancer Society).
- Trial name
- NCT00745095
- Testing
- Neostigmine
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Colon Cleansing
Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing
The purpose of this study is to compare the safety and efficacy of OsmoPrep tablets versus HalfLytely and Bisacodyl Tablet Bowel Prep Kit in subjects who are undergoing colonoscopy.
- Trial name
- NCT01427296
- Testing
- Polyethylene glycol, Oral sodium phosphate solution
- Where
- 18 sites in United States
- Volunteers
- 2,154 people
- Sponsor
- Bausch Health Americas, Inc.
Anesthesia, Endoscopy
Sedation Regimens in GI Endoscopy
This is a noninferiority study designed to examine whether conscious sedation with midazolam alone results in efficacy and safety that is not inferior to the combination of midazolam and fentanyl.
- Conditions
- Anesthesia, Endoscopy, Colonoscopy, Conscious Sedation
- Trial name
- NCT04807101
- Testing
- midazolam alone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Greg S Cohen MD LLC
Need for Bowel Preparation
Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
To study the efficacy and safety of Prepopik® in children aged 9 to 16 years for overall colon cleansing in preparation of colonoscopy
- Trial name
- Prepopik PREA (NCT01928862)
- Testing
- Prepopik® ½ Sachet x 2 (9-12 years), Prepopik® 1 Sachet x 2 (9-12 years), Oral polyethylene glycol (PEG) based preparation (9-12 years)
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ferring Pharmaceuticals
Sedation
A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous Sedative for Diagnostic or Therapeutic Colonoscopy in Adult Special Populations
The purpose of this study is to evaluate the safety and efficacy of LUSEDRA (fospropofol disodium) and to determine whether a dose lower than currently approved can provide effective moderate sedation required to complete…
- Trial name
- NCT01127438
- Testing
- fospropofol disodium Subgroup 1 Lower Dose, fospropofol disodium Subgroup 1 Approved Dose, fospropofol disodium Subgroup 2 Lower Dose
- Where
- 23 sites in United States
- Volunteers
- 153 people
- Sponsor
- Eisai Inc.
Colonoscopy
Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE)
In this study, the investigators will evaluate the ability of the Magnetic Flexible Endoscope (MFE) to travel through the human colon.
- Trial name
- NCT05833789
- Testing
- Magnetic Flexible Endoscope (MFE)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Vanderbilt University Medical Center
Type 2 Diabetes Mellitus, Colonoscopy
Abnormal Blood Sugar Tests in Diabetic Patients During Colonoscopy Preparation
Type 2 diabetes is rapidly increasing globally and has been associated with an increased risk of colorectal cancer. Therefore, the numbers of diabetic patients who will undergo colonoscopic screening are expected to grow…
- Trial name
- NCT03109951
- Testing
- Colonoscopy preparation using polyethylene glycol
- Where
- South Korea
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Catholic Kwandong University
Colonoscopy
Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446312
- Testing
- Bowel Prep
- Where
- 34 sites in United States
- Volunteers
- 500 people
- Sponsor
- Braintree Laboratories
Colon Staining in Preparation for Colonoscopy
Colon Staining Efficacy of Single Oral Doses of Methylene Blue MMX
To describe and evaluate the mucosal staining efficacy of Methylene Blue MMX® tablets after total oral doses of 150 or 200 mg in patients undergoing a full colonoscopy for various reasons.
- Trial name
- CRO-11-108 (NCT03287219)
- Testing
- Methylene Blue MMX 25 mg modified release tablets
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Colonoscopy, Adjunct Anesthesia Medication
Diphenhydramine as an Adjunctive Sedative in Patients on Chronic Opioids
To access the efficacy of adding diphenhydramine as adjunct to improve sedation and to reduce the amount of standard sedatives used during colonoscopy in patients on chronic opioids.
- Trial name
- NCT01967433
- Testing
- Diphenhydramine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Oklahoma
Gastrointestinal Dysfunction, Alteration of Cognitive Function
The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy
There are different sedation regimes for lower gastrointestinal system endoscopy which can be administered by anesthesiologists and non-anesthesiologists.
- Trial name
- NCT02486328
- Testing
- Midazolam, Meperidine, Remifentanil
- Volunteers
- 103 people
- Sponsor
- Ufuk University