Clinical trials: Colorectal Disorders
Colorectal Disorders
ColonCancerCheck Mailed Invitations: An Evaluation
This study evaluates effectiveness of mailed invitations for colorectal cancer screening among screen-eligible Ontarians who are due for screening.
- Trial name
- NCT02364895
- Testing
- Males control group: Deferred letter, Males Group 1: Current CCC invitation letter, Males Group 2: New letter with neutral gender content
- Volunteers
- 75,317 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Urinary Retention
Optimal Duration of Indwelling Urinary Catheter Following Pelvic Surgery
There is no general agreement about the optimal duration of postoperative urinary drainage, with relevant literature reporting durations ranging from 1 to 10 days.
- Trial name
- NCT01923129
- Testing
- Prazosin given 6 hours prior to catheter removal in the 24 hour group
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Colorectal Cancer, Colorectal Neoplasms
Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia
In order to encourage the population at risk to participate in colorectal cancer screening, this clustered trial intends to determine the efficacy of specific messages(Nudge), single FIT testing, and the primary care physician's…
- Trial name
- ColonCancer (NCT05785975)
- Testing
- Certain ommunications(Nudge), community-outreach(landline call), and single FIT testing
- Where
- Saudi Arabia
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Neoplastic Cells, Circulating
The Detection of Circulating Tumor Cells (CTCs) in Patients With Colorectal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Circulating tumor cells (CTCs) have the potential to provide a surrogate for'real-time biopsy' of tumor biological activity. Enumeration and molecular characterization of CTCs in colorectal cancer could play an important role in…
- Trial name
- NCT02450422
- Testing
- Flow cytometry (FCM), RT-PCR
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Breast Cancer, Colorectal Cancer
Nurse-led Proactive Telephone Follow-up With Patients After Completion of Primary Cancer Treatment
The goal of this randomized study is to test and evaluate nurse-led telephone follow-up intervention in patients primarily curatively treated for breast cancer, colorectal cancer, and prostate cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT06223022
- Testing
- Proactive nurse-led telephone follow-up
- Where
- Sweden
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Umeå University
Rectal Neoplasms, Colon Neoplasms
Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer
Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide. About 1 in 4 people with CRC already have cancer spread (metastasis) when first diagnosed, and about half develop spread during their illness.
- Conditions
- Rectal Neoplasms, Colon Neoplasms, Microbiota, Metagenome
- Trial name
- NCT07154173
- Testing
- Biospecimen Collection Procedure
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Breast Cancer, Prostate Cancer
Integration of Cancer Health Activities Into African American Churches
The proposed project will compare two ways to apply a known-effective cancer educational strategy through African American churches: 1) a standard method vs.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT03178383
- Testing
- Project HEAL, Project HEAL 2.0
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Rectal Cancer, Gut Microbiomes
Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer
Rectal cancer patients who received low anterior resection combined with ileostomy may effectively reduce the probability of anastomotic leakage after surgery.
- Conditions
- Rectal Cancer, Gut Microbiomes, Autologous Probiotic Transplantation, Defunctioning Ileostomy
- Trial name
- NCT07366047
- Testing
- Autologous Probiotics
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Colorectal Neoplasms
Initiation of Colon Cancer Screening in Veterans or "Start Screening Now"
Initiation of colon cancer screening in veterans is a theory-based stepped intervention to increase first time colorectal cancer screening (CRCS) among male and female veterans age 50 and over.
- Trial name
- SSN (NCT01079533)
- Testing
- Stepped CRCS Interventions, Control
- Where
- United States
- Volunteers
- 1,892 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer
Split Dose Polyethylene Glycol (PEG) + Clear Fluids Versus Split Dose PEG + Low-Residue Diet
The objective of the study is to examine the effect of adding a strict low-residue lunch on the day before colonoscopy has on clinical efficacy and patient tolerability of bowel preparation, with patients receiving split-dose…
- Trial name
- BP (NCT01610895)
- Testing
- Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions, Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions
- Where
- Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Adenoma, Colorectal Cancer
Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®
The study is intended to compare the detection rate obtained by performing G-EYE® high definition colonoscopy vs. the detection rate obtained by performing ECV high definition colonoscopy.
- Trial name
- NCT04708951
- Testing
- ENDOCUFF VISION® device, G-EYE® colonoscope
- Where
- 3 sites in United States, Germany
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colorectal Cancer, Colon Rectal Resection
Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer
Study of Oxidative stress Markers (F2 Isoprostanes for lipid peroxidation, Carbonyl groups for protein peroxidation, 3 Nitrotyrosine for damage by nitrogens, and 8-Hydroxyguanosine for RNA peroxidation)in patients with colorectal…
- Conditions
- Colorectal Cancer, Colon Rectal Resection, Oxidative Stress
- Trial name
- NCT01470586
- Testing
- Surgery for colorectal cancer
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. Hatzikosta General Hospital
Cancer, Head and Neck Cancer
EXCEL: Exercise for Cancer to Enhance Living Well
Project EXCEL will provide community or online exercise programs to rural and remote and under-served cancer survivors, as well as encourage participants to become life-long exercisers.
- Conditions
- Cancer, Head and Neck Cancer, Colon Cancer, Breast Cancer
- Trial name
- EXCEL (NCT04478851)
- Testing
- Group Exercise Classes
- Where
- 3 sites in Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cancer of Colon
Choice Architecture and Colorectal Cancer Screening Outreach
This pilot study is a 3-arm randomized control trial assessing the effectiveness of sequential or active choice in CRC (colorectal cancer) screening outreach vs.
- Trial name
- NCT03246438
- Testing
- Colonoscopy only, Colonoscopy outreach + mailed FIT follow-up, Colonoscopy + Mailed FIT outreach and follow-up
- Where
- United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Colorectal Cancer
Colorectal Cancer Detection by Means of Optical Fluoroscopy
The aim of the present prospective study was to investigate the fluorescence emission of human blood plasma of patients with colorectal cancer.
- Trial name
- NCT01286064
- Testing
- Optical Fluoroscopy
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colorectal Polyp, Obesity
Feasibility and Colorectal Benefits of Pulses Supplementation
Beans are a forgotten staple food that shows promise in improving health. The goal of this study is to look at how bean supplementation affects metabolic and bowel health.
- Trial name
- NCT06032104
- Testing
- Dry beans, Usual diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Colorectal Carcinoma
Comparative Study of Lubiprostone and PEG Preparation Versus Conventional PEG Preparation for Colonoscopy
Lubiprostone as an adjunct to the standard bowel preparation regime the quality of bowel preparation can be improved for a good colonoscopic examination without missing lesions and complications.
- Trial name
- Lubiprostone (NCT01324284)
- Testing
- Lubiprostone
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Colorectal Carcinoma
Implementation Research to Increase Colorectal Cancer Screening Rates Among Low Income and Ethnic Minority Groups
This clinical trial implements research strategies to increase colorectal cancer (CRC) screening rates among low income and ethnic minority groups.
- Trial name
- NCT06090643
- Testing
- Best Practice, Consultation, Educational Intervention
- Where
- United States
- Volunteers
- 9,745 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Benign Polyps of Large Intestine
Resect and Discard Approach to Diminutive Colonic Polyps
Resect and discard (RD) is a new paradigm for management of diminutive colorectal polyps wherein histology is determined by real-time endoscopic imaging; polyps are then resected and discarded rather than sent for…
- Trial name
- RD (NCT01877525)
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Colon Cancer
A Survey on Attitudes on Financial Incentives
The study concerns a survey of attitudes of the public on issues around personal responsibility for health and the use of financial incentives to promote health in the U.S. and Germany.
- Trial name
- NCT01457976
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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