Clinical trials: Colorectal Polyp
Colorectal Cancer, Colorectal Adenoma
Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp
A study of carcinogenesis-related molecular markers in the patients with colorectal cancer and colorectal adenoma.
- Trial name
- NCT05638542
- Where
- South Korea
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Polyps
Experience and Enhancement: Improving Colonoscopic Polyp Detection
The study looks at 2 hypotheses in 2 patient groups: 1. Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists? 2.
- Trial name
- NCT00237276
- Testing
- colonoscopy
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Adenoma, Polyps
Inspection of the Colon Using a Retrograde Viewing Device for Detection of Colorectal Polyps
During standard colonoscopy a substantial number of colorectal polyps may be missed. Previous studies have found a 12-28% of miss rate for all polyps, a 31% for hyperplastic polyps and 6-27% for adenomas.
- Trial name
- NCT04107376
- Testing
- Retroviewing endoscopy
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colorectal Cancer, Polyps
Aspirin/Folate Prevention of Large Bowel Polyps
This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00272324
- Testing
- Aspirin, Folate
- Where
- 9 sites in United States, Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colon Cancer, Rectal Cancer
Clinical Study-evaluate Performance&Safety "Aer-O-Scope" in Colon of Low Risk Patients
A double center study to evaluate the safety and efficacy of the Aer-O-Scope in traveling through the colon in low risk subjects.
- Trial name
- NCT00867724
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colorectal Neoplasms
Unprepped CT Colonography
It is our objective to improve the performance of CTC in the prepared colon, and to validate CTC in the unprepared colon for the detection of colorectal neoplasia.
- Trial name
- NCT00586053
- Where
- United States
- Volunteers
- 1,255 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer, Colorectal Adenomatous Polyp
Multiple Screening Methods for the Detection of Chinese Colorectal Advanced Adenomatous Polyps and Cancer
The primary objective is to determine the sensitivity and specificity of two Colorectal Cancer (CRC) screening methods, including stool DNA test and blood mRNA test, for colorectal cancer in Chinese population, with colonoscopy…
- Trial name
- NCT03411707
- Testing
- Stool DNA test
- Where
- 3 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Hypoxia, Gastric Polyp
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol.
- Conditions
- Hypoxia, Gastric Polyp, Colon Cancer, Esophageal Cancer
- Trial name
- NCT06081647
- Testing
- the COMBO Endoscopy Oropharyngeal Airway, Regular Nasal Cannula
- Where
- 10 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Colonoscopy, Polypectomy
Comparison of Jumbo and Hot Biopsy Forceps
Cold forceps polypectomy and hot biopsy forceps electrocauterization (HBF) are still widely used methods for endoscopic resection of diminutive colorectal polyps (DCPs)(polyps smaller than 5 mm).
- Trial name
- NCT02188316
- Testing
- Jumbo forceps, Hot biopsy forceps
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Camlıca Erdem Hospital
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Colorectal Adenoma, Colorectal Polyp
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
The aim of this study is to assess the efficacy of Ultivision Artificial Intelligence (AI) Software in detecting adenomas in screening colonoscopy procedures. The safety of Ultivision AI Software will also be assessed.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
- Trial name
- AIDA (NCT04196088)
- Testing
- Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
- Where
- 9 sites in United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Docbot, Inc.
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Colorectal Neoplasms, Gastrointestinal Microbiome
Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue
This is a prospective, multicenter, single-arm clinical investigation designed to evaluate the accuracy of the Gixam™ System in identifying subjects with colorectal adenomas compared to optical colonoscopy.
- Trial name
- NCT06305364
- Testing
- Gixam
- Where
- 3 sites in United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Jubaan Ltd.
Serrated Polyp, Colorectal Neoplasms
Increasing Serrated Polyp Detection With a Brief Awareness Training
In this non-randomized controlled trial, a semi-random group of Dutch endoscopist receive an oral training about the significance of serrated polyps.
- Trial name
- NCT03902899
- Testing
- Educational intervention (oral presentation)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colorectal Cancer, Polyp
Performance Evaluation of the NaviAid™ G-Eye System
The purpose of this study is to compare the additional diagnostic yield obtained by performing NaviAid™ G-Eye procedure vs. the diagnostic yield obtained by performing standard colonoscopy procedure.
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01552200
- Testing
- Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure, Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
- Where
- 4 sites in Germany, Israel
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Cancer, Adenomatous Polyps
Exploratory Study of a Novel Based rbcDNA Liquid Biopsy Technique for Colorectal Cancer Early Detection
Exploration of a novel rbcDNA liquid biopsy technique for early detection of colorectal cancer is a promising development in the field of disease diagnosis and screening.
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- NCT05875584
- Testing
- rbcDNA test
- Where
- China
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colorectal Polyp
Assessment of Endoscopic Tip Control Using a Novel Score Based on the Snare Tip Soft Coagulation of Polypectomy Margin Defects
Colorectal cancer is the third most common malignancy worldwide and the second leading cause of cancer related death with approximately 880 792 deaths every year (9,2% of the global yearly 9.6 million cancer deaths).
- Trial name
- NCT05660317
- Testing
- Tip control score
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Polyp, Colorectal Adenoma
Social Software-Based Intelligent Management System for Bowel Preparation
Colorectal cancer (CRC) is one of the most common malignancies worldwide, and colonoscopy is an important method for CRC screening and early detection.
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Bowel Preparation, Artificial Intelligence
- Trial name
- NCT07901257
- Testing
- AI-assisted Bowel Preparation Management, Conventional Bowel Preparation Management
- Where
- China
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colonic Polyp
Study of a Screening Blood Test to Determine Patients' Potential Risk of Adenomatous or Advanced Colon Polyps (ACPs)
The aim of this study is to develop a blood test to determine which patients are at risk for pre-cancerous colon polyps (ACPs: Advanced Colon Polyps).
- Trial name
- NCT01062035
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic