Clinical trials: Colorectal Surgery
Colon Neoplasms, Crohn Disease (CD)
Feasibility Study of the SEGER Device in Laparoscopic Gastrointestinal Surgery
This is a first-in-human feasibility study designed to evaluate the safety and performance of the SEGER device in patients undergoing elective laparoscopic gastrointestinal surgery requiring intracorporeal anastomosis.
- Conditions
- Colon Neoplasms, Crohn Disease (CD), Obesity & Overweight
- Trial name
- SEGER-FIH (NCT07508592)
- Testing
- SEGER Device
- Where
- El Salvador
- Volunteers
- 10 people
- Sponsor
- Seger Surgical Solutions
Diabetes Mellitus, Type 2, Surgery
Carbohydrate Loading and Diabetes in Colorectal Surgery
The goal of this study is to evaluate the feasibility of conducting a large study that would assess the safety of carbohydrate drinks (i.e. juice) prior to elective colorectal surgery in patients with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Surgery, Surgery--Complications
- Trial name
- NCT04410419
- Testing
- Pre-operative carbohydrate drink
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- University of Alberta
Liver Tumors
Freehand Ultrasound Elasticity Imaging in Liver Surgery
The purpose of this study is to investigate the potential for visualizing radiofrequency-induced (RFA) and microwave-induced (MWA) hepatic thermal ablation lesions using a novel, high resolution, and freehand ultrasound…
- Trial name
- IOUS (NCT00942383)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Anti-bacterial Agents, Pharmacokinetics
The Expected Advantage of Administering Prophylactic Antibiotics Using Target- Concentration Controlled Infusion
Preoperative antimicrobial prophylaxis is a key element for the prevention of surgical site infection, the most common type of nosocomial infection in surgical patients.
- Conditions
- Anti-bacterial Agents, Pharmacokinetics, General Surgery
- Trial name
- NCT05253339
- Testing
- target-controlled infusion (one of the administration methods), Standard administration method
- Where
- South Korea
- Volunteers
- 2,494 people
- Sponsor
- Asan Medical Center
Colorectal Neoplasms Malignant
Effects of COVID-19 Pandemic on the Outcomes of Colorectal Cancer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been identified as the cause of the Coronavirus disease 19 (COVID-19), which was initially reported in December 2019 in China and has since rapidly spread…
- Trial name
- COVID-CRC (NCT04712292)
- Testing
- Surgical procedure for confirmed or suspected colorectal cancer
- Where
- 45 sites in Italy
- Volunteers
- 15,000 people
- Sponsor
- University of Bologna
Anastomotic Leakage
The Relationship Between Drainage Fluid and Anastomotic Leakage After Colorectal Cancer Surgery
A prospective and analytical study on the detection of early anastomotic leakage by abdominal drainage fluid after colorectal cancer surgery. pay attention to indicators including bilirubin
- Trial name
- NCT05191602
- Testing
- drainge fluid
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Southwest Hospital, China
Colon Cancer, Colon Neoplasm
Long-term Results in Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy
Advantages of laparoscopic right colectomy with intracorporeal anastomosis (IA) compared to extracorporeal anastomosis (EA) are widely studied.
- Conditions
- Colon Cancer, Colon Neoplasm, Malignant Neoplasm, Colon Neoplasia
- Trial name
- NCT05446558
- Testing
- Intracorporeal anastomosis, Extracorporeal anastomosis
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Colorectal Cancer, Liver Metastases
Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis
Trans arterial chemoembolization using Irinotecan Drug-eluting Beads before liver surgery for patients with primarily unresectable colorectal liver metastasis
- Trial name
- NCT04912258
- Testing
- Trans arterial chemoembolization with Irinotecan Drug-eluting Beads
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Colorectal Cancer
A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer
The purpose of this study is to evaluate oncological outcome of patients for T3 and T4 colorectal cancer undergoing laparoscopic versus open surgery.
- Trial name
- NCT00147134
- Testing
- open colectomy, laparoscopic colectomy
- Where
- 26 sites in Japan
- Volunteers
- 1,050 people
- Sponsor
- Haruhiko Fukuda
Anastomotic Leak
Risk Factors Associated With Anastomotic Leak and Perioperative Mortality in Elderly
This is a retrospective cohort study of all consecutive patients who underwent colon or rectal resection, between the years 2012-2017 at Rabin Medical Center, a tertiary referral center in Israel.
- Trial name
- NCT04518384
- Testing
- colon or rectum resection
- Where
- Israel
- Volunteers
- 536 people
- Sponsor
- Rabin Medical Center
Urinary Retention, Rectal Cancer
Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2)
The objective of this trial is to investigate the effect of bladder training on the incidence of re-catheterization after proctectomy.
- Conditions
- Urinary Retention, Rectal Cancer, Urinary Catheterization
- Trial name
- NCT06217016
- Testing
- ICCAUT, Free drainage
- Where
- China
- Sponsor
- The First Hospital of Jilin University
Locally Advanced Colorectal Carcinoma, Recurrent Colorectal Carcinoma
Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
*As of June 2026- Phase I has been completed and we are now in Phase II. This phase I/II trial studies the side effects and how well fluorescence image guided surgery followed by intraoperative photodynamic therapy for improving…
- Conditions
- Locally Advanced Colorectal Carcinoma, Recurrent Colorectal Carcinoma, Stage III Colorectal Cancer
- Trial name
- NCT06307548
- Testing
- Aminolevulinic Acid, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Roswell Park Cancer Institute
Colon Cancer, Colon Adenocarcinoma
Survival Outcomes by Tumor-Node Stage and Recurrence Patterns in Colon Cancer After Radical Surgery
Colon cancer is one of the most common cancers worldwide, and even after curative (radical) surgery, some patients develop recurrence or distant metastasis.
- Conditions
- Colon Cancer, Colon Adenocarcinoma, Colon Cancer Stage III, Colon Cancer Stage I
- Trial name
- STARS (NCT07167147)
- Where
- Taiwan
- Volunteers
- 7,259 people
- Sponsor
- Chang Gung Memorial Hospital
Metastatic Colorectal Cancer
"Cancersensor" Metastasis Resection
Observational, non randomized study aimed at measuring the effect of surgical resection of metastasis in the urinary concentrations of physiological modified nucleosides in 45 patients with metastatic colorectal cancer.
- Trial name
- NCT01693848
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Colorectal Cancer
Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- PETACC-6 (NCT00766155)
- Testing
- capecitabine, oxaliplatin
- Volunteers
- 1,094 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Colon Cancer
Laparoscopic Surgery Versus Robot Surgery for Right-side Colon Cancer: Short-term Outcome of a Randomised Clinical Trial
The recent introduction of robotic surgical system has revolutionized the field of minimally invasive surgery. The investigators hypothesized that adoption of a robotic surgical system for patients with right-side colon cancer…
- Trial name
- NCT01042743
- Testing
- robot-assisted surgery, laparoscopic right-hemicolectomy
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kyungpook National University Hospital
Rectal Cancer Stage II, Rectal Cancer Stage III
Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma
The objective of the study is to provide proof that a MRI based preoperative radiochemotherapy in patients with locally advanced rectal carcinoma allows limiting RCT to high risk patients without increase of locoregional…
- Trial name
- OCUM (NCT01325649)
- Testing
- total mesorectal excision / long course radiochemotherapy, long course 5-FU bases radiochemotherapy
- Where
- Germany
- Volunteers
- 1,051 people
- Sponsor
- Johannes Gutenberg University Mainz
Gastric Cancer, Colorectal Cancer
Status of Management of Surgery in Beijing During COVID-19
This is a multi-centered, retrospective, observational study aimed at observing the current status of the management of gastrointestinal surgery during the COVID-19 pandemic, particularly the changes on surgery protocols and…
- Conditions
- Gastric Cancer, Colorectal Cancer, Gastrointestinal Disease
- Trial name
- NCT04401124
- Testing
- no intervention
- Volunteers
- 500 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Tumors
Effect of Peritoneal Lavage With Clindamycin-Gentamicin Solution & Oncologic Outcome
Antibiotic lavage reduces bacterial contamination and decreases SSI infection rate. SSI leads to an immunocompromised situation, leaving unattended the neoplasm.
- Trial name
- NCT02399059
- Testing
- Antibiotic lavage, Normal saline lavage
- Volunteers
- 106 people
- Sponsor
- Hospital General Universitario Elche
Postoperative Ileus, Anastomotic Leak
SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition
The main objective is to investigate the effects of perioperative nutrition on postoperative ileus and anastomotic leakage in patients undergoing colorectal surgery.
- Trial name
- SANICSII (NCT02175979)
- Testing
- enriched enteral nutrition, standard
- Where
- 5 sites in Denmark, Netherlands
- Volunteers
- 280 people
- Sponsor
- Misha D.P. Luyer
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