Clinical trials: Colorectal Surgical Procedure Outcomes
Colorectal Surgical Procedure Outcomes
Procedure Outcome Predictor (POP) Using the Complement Cascade
Current post-operative monitoring of patient recovery consists measuring two blood markers C-reactive protein (CRP) and White Blood Cell Count (WBC). However, these are slow to respond to the onset of infection.
- Trial name
- CPOP (NCT02531789)
- Testing
- Observation
- Volunteers
- 45 people
- Sponsor
- University of Exeter
Colorectal Cancer, Imaging
Metabolism Imaging-genomics for Predicting the Surgical Outcomes of Colorectal Cancer
In this study, the investigators constructed an imaging-metabolism prediction model for colorectal cancer by analysing the imaging and metabolomics features of colorectal cancer, in order to further adjust and guide the treatment…
- Conditions
- Colorectal Cancer, Imaging, Metabolomics, Prognosis
- Trial name
- NCT06614660
- Testing
- Metabolism genomics and imaging genomics
- Where
- China
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University
Ulcerative Colitis, Rectal Cancer
Surgical and Oncological Outcomes in Patients With Ulcerative Colitis-associated Rectal Cancer
This is a retrospective observational study to investigate the short-term surgical outcomes, and long-term oncological outcomes of patients diagnosed with Ulcerative colitis and rectal cancer.
- Trial name
- UC-RectalK (NCT04659148)
- Testing
- Total proctocolectomy
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Rectal Cancer
RAPIDO vs LCRT vs Upfront Surgery - a Prospective Cohort Study
Aim: We evaluated the surgical outcomes of 3 groups of patients with rectal cancers - RAPIDO vs standard long course radiotherapy (LCRT) vs upfront surgery to objectively determine the effects of TNT on TME.
- Trial name
- RAPIDO (NCT06212128)
- Testing
- RAPIDO TNT, LCRT
- Volunteers
- 57 people
- Sponsor
- Sengkang General Hospital
Colo-rectal Cancer
Multicentric National Italian Analysis of Textbook Outcome in Colorectal Cancer Surgery
Colorectal cancer (CRC) is the third most common malignancy worldwide, with more than 1.9 million new cases reported annually. Survival among patients with CRC depends on several factors, including disease stage at diagnosis, the…
- Trial name
- ATOCCS (NCT07718919)
- Where
- Italy
- Volunteers
- 6,129 people
- Sponsor
- Academy of Applied Medical and Social Sciences, Poland
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Colorectal Adenocarcinoma, Colorectal Surgery
Trends and Outcomes in Laparoscopic Versus Open Surgery for Rectal Cancer
Retrospective cohort study used to analyze trends in minimally invasive versus open surgery in colorectal surgery, over time, in outcome in the laparoscopic, robotic and open surgery groups in patients receiving colorectal…
- Trial name
- NSQIPc (NCT03683446)
- Testing
- Laparoscopic rectal surgery, Open rectal surgery
- Volunteers
- 31,795 people
- Sponsor
- Catherine H. Davis, MD
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Colon Cancer Stage I, Colon Cancer Stage II
Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
The investigators will assess and compare Surgical, pathological and oncological outcomes between two laparoscopic procedures conventional colectomy versus complete mesocolic excision for operable colon cancer cases in Upper Egypt
- Trial name
- NCT05421702
- Testing
- laparoscopic conventional colectomy, laparoscopic complete mesocolic excision
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Home Care, Enhanced Recovery
The Impact of AI-Assisted Nursing Care Intervention Within the Enhanced Recovery Framework on Outcomes of Colorectal Surgery Patients
Colorectal cancer is one of the most common cancers worldwide, affecting a large number of people each year (Bray et al., 2022). Surgical intervention remains the gold standard in treatment.
- Conditions
- Home Care, Enhanced Recovery, Colo-rectal Cancer, Colorectal Surgery
- Trial name
- NCT07369219
- Testing
- Educational intervention, Standard maintenance therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bahçeşehir University
Colorectal Cancer, Adhesion
Mechanical Ileus in the Era of Minimally Invasive Colorectal Surgery
The present study was to investigate if the incidence, patterns and surgical outcomes of mechanical ileus have changed in the era of minimally invasive surgery (MIS).
- Trial name
- NCT05999162
- Testing
- Minimally invasive surgery
- Where
- Taiwan
- Volunteers
- 1,544 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer (CRC), Robotic Surgical Procedures
Robot-assisted Surgery for Colorectal Cancer Resection: A Population-based Analysis of Prevalence, Trends and Outcomes
The objective of this research project is to conduct a comparative analysis of short- and long-term outcomes between conventional laparoscopic and robot-assisted resection procedures for colorectal cancer.
- Conditions
- Colorectal Cancer (CRC), Robotic Surgical Procedures, Laparoscopic Abdominal Surgery, Outcome Assessment
- Trial name
- RoChiKoKa (NCT06959849)
- Testing
- Use of robot surgical system
- Volunteers
- 128,000 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Colorectal Anastomosis
EAST-west Colorectal Study
Colorectal resection due to benign and malignant diseases is a commonly performed procedure. The continuity of the gastrointestinal tract is re-established by creating an anastomosis.
- Trial name
- EAST-west (NCT05544487)
- Testing
- Colorectal Anastomosis
- Volunteers
- 300 people
- Sponsor
- National and Kapodistrian University of Athens
Rectal Cancer, Quality of Life
Quality of Life in RECTal Cancer - a Prospective Multicenter Cohort Study
Rectal cancer is a common type of cancer occuring more frequently in men but also common in women. Almost 60% of the patients survive 5-years and the treatment has been continuously developed in the last three decades.
- Conditions
- Rectal Cancer, Quality of Life, Surgery
- Trial name
- QoLiRECT (NCT01477229)
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Sahlgrenska University Hospital
Endometriosis
Incidence of Different Surgical Technics for Colorectal Deep Infiltrating EndoMetriosis on the Post-operative Fertility and Pregnancy Outcomes
Endometriosis is a disease that is very present on the current media scene. Its symptoms are very nonspecific and numerous. (dysmenorrhea, dyspareunia, dyschezia, urinary functional signs, infertility, chronic pelvic pain, etc.)…
- Trial name
- Endo-Metrios (NCT04681898)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- University Hospital, Strasbourg, France
Surgery
Outcomes of Intrathecal Analgesia in Colorectal Surgery
Multimodal analgesia, sometimes including intrathecal analgesia (IA), is essential in any enhanced recovery pathway (ERP). This study aimed to evaluate the safety, feasibility, and optimal IA regimen in colorectal surgical…
- Trial name
- NCT03411109
- Testing
- Hydromorphone Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 601 people
- Sponsor
- Mayo Clinic
Rectal Neoplasms
Selection of Surgical Technique in Rectal Cancer
Currently, there is no prediction scale available to identify patients with rectal neoplasms as technically complex in the middle and lower thirds; that is, those who are at high risk of affected circumferential margins and low…
- Trial name
- TECARE (NCT06442215)
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Laparoscopic Colectomy, Cancer Colon
Laparoscopic Colectomies In Management of Colonic Cancers
The aim of this study is to compare the Surgical outcomes after laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies in management of colonic cancers .
- Conditions
- Laparoscopic Colectomy, Cancer Colon, Intracorporeal Anastomosis
- Trial name
- NCT04972994
- Testing
- laparoscopic intracorporeal versus extracorporeal anastomosis for right and left hemicolectomies
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University