Clinical trials: Combat
Exercise Adaptation, Aerobic Capacity
AEROBIC ADAPTATION AND BIOMARKER RESPONSES IN COMBAT ATHLETES
This randomized controlled study investigates the effects of sport-specific training on aerobic adaptation and circulating biomarker responses in trained combat athletes.
- Conditions
- Exercise Adaptation, Aerobic Capacity, Athletic Performance, Combat Sports Training
- Trial name
- AERO-BIO (NCT07473440)
- Testing
- SPORT-SPECIFIC CONDITIONING PROGRAM
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Dehydration in Children, Dehydration
The Impact of Brief One-time Education and Coach Encouragement on Hydration Status in Child Judo Athletes
Due to the lack of any comparative study related to effect of different hydration processes, this study aimed to compare the effectiveness of coach encouragement and hydration education in maintaining hydration status in child…
- Trial name
- NCT06992817
- Testing
- Hydration-Coach Encouragement, Short Hydration Informative Session
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Mild Traumatic Brain Injury (mTBI), Brain Injury
A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury
The use of Hyberbaric Oxygen Therapy (HBOT) would be a new treatment plan rather than conventional rest. If effective, this new use technology would add to the clinical treatment among mild traumatic brain injury (mTBI) patients.
- Conditions
- Mild Traumatic Brain Injury (mTBI), Brain Injury, Concussion
- Trial name
- NCT06901310
- Testing
- Hyberbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Michael Harl
PTSD, Post Traumatic Stress Disorder PTSD
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
The goal of this clinical trial is to evaluate the safety and effectiveness of the gammaCore non-invasive vagus nerve stimulation (nVNS) device as an additional treatment for symptoms of post-traumatic stress disorder (PTSD) in…
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT07523685
- Testing
- non-invasive vagus nerve stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Acacia Clinics
Stress Disorders, Post Traumatic, Substance-Related Disorders
Cognitive Therapy for PTSD in Addiction Treatment
The purpose of this phase of the study is to assess the feasibility of a cognitive behavioral therapy for post-traumatic stress disorder (PTSD) in persons receiving outpatient services at an addiction treatment program.
- Trial name
- NCT00685451
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Sports Performance, Respiratory Muscle Function
Inspiratory Muscle Warm-Up in Combat Athletes
The aim of this study is to investigate the effects of inspiratory muscle warm-up (IMW) on technical performance and physiological responses in combat athletes.
- Conditions
- Sports Performance, Respiratory Muscle Function, Cardiorespiratory Responses
- Trial name
- NCT07481916
- Testing
- POWERbreathe
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Military Family, Brain Injuries, Traumatic
Effects of PSTon Mental Health Outcomes in Caregivers of Post-9/11 Combat Veterans With a Traumatic Brain Injury
The primary aim of this study is to assess the efficacy of PST for positively impacting distressed military family caregiver's depression and burden levels (secondary outcomes), ultimately enhancing their mental health quality of…
- Trial name
- NCT03211884
- Testing
- Problem-Solving Thearpy
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Stress Disorders, Post-Traumatic
Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD
The purpose of this study is to establish the efficacy of Magnetic Resonant Therapy in treating Post Traumatic Stress Disorder in Veterans.
- Trial name
- NCT02268084
- Testing
- Magnetic EEG/ECG-guided Resonance Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Wave Neuroscience
Posttraumatic Stress Disorder
Telemental Health and Cognitive Processing Therapy for Rural Combat Veterans With Posttraumatic Stress Disorder
The immediate objective of this project was to evaluate the clinical effectiveness of a telemental health modality (video-teleconferencing) for providing an evidence-based group intervention (Cognitive Processing Therapy; CPT) to…
- Trial name
- CPTVTEL (NCT00879255)
- Testing
- Cognitive Processing Therapy Group Videoteleconference, Cognitive Processing Therapy Group In-Person
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- US Department of Veterans Affairs
Resistance Training
Traditional Versus Cluster Resistance Training in Striking Combat Sport Athletes
This randomized controlled trial compared the effects of traditional and cluster resistance training on neuromuscular performance in amateur striking combat sport athletes.
- Trial name
- TRG-CLG (NCT07653425)
- Testing
- Traditional, Cluster
- Where
- Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Muscle Protein Synthesis, Endotoxemia
Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease
This study compares three different protein supplements (casein, whey and leucine-enriched whey) and their effect on post-inflammatory muscle waste in a model of acute disease.
- Conditions
- Muscle Protein Synthesis, Endotoxemia, Nutrition, Milk Protein
- Trial name
- NCT03319550
- Testing
- Casein, Whey, Leucine-enriched whey
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Oral Cavity Squamous Cell Carcinoma, Head and Neck Cancer
H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)
This is a multicenter, single arm Phase 2B study in subjects with locally advanced oral cavity squamous cell carcinoma (OCSCC) with surgically resectable disease.
- Trial name
- NEO COMBAT XL (NCT07484139)
- Testing
- XL092, Pembrolizumab
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
PTSD
Delivery of Self Training and Education for Stressful Situations-Telephone Version
This study will evaluate a telephone-delivered cognitive-behavioral psychotherapy intervention designed for primary care treatment of combat-exposed service members with PTSD.
- Trial name
- DESTRESS-T (NCT01502449)
- Testing
- DESTRESS-T, Optimized Usual Care (OUC)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Uniformed Services University of the Health Sciences
Stress Disorders, Post Traumatic
Exposure Therapy for Active Duty Soldiers With Post Traumatic Stress Disorder
This study is evaluating the efficacy of virtual realty exposure therapy (VRET)by comparing it to prolonged exposure therapy (PE) and a waitlist (WL) group for the treatment of post traumatic stress disorder (PTSD) in active duty…
- Trial name
- VRPE (NCT01193725)
- Testing
- Prolonged Exposure Therapy (PE), Virtual Reality Exposure Therapy (VRET), Waitlist
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- National Center for Telehealth and Technology
Posttraumatic Stress Disorder
Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms
This project will study whether a new therapy that includes the practice of forms of meditation is helpful for combat veterans returning from deployments in Iraq or Afghanistan suffering with posttraumatic stress disorder (PTSD).
- Trial name
- NCT01347749
- Testing
- Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan
Stress Disorders, Post Traumatic
Treatment of Post-traumatic Stress Disorder With High Doses of Escitalopram
The study evaluates the hypothesis that large doses of Escitalopram will reduce symptoms of chronic post-traumatic stress disorder (PTSD) in adult civilian survivors of traumatic events.
- Trial name
- NCT00736021
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Hadassah Medical Organization
Nerve Block, Nerve Blocks
Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation
This randomized study will examine whether ultrasound-guided regional anaesthesia (a nerve block) contributes to new or worsening peripheral nerve problems after blast-related limb trauma.
- Conditions
- Nerve Block, Nerve Blocks, Nerve Injury, Blast Injury
- Trial name
- BRAVE (NCT07879508)
- Testing
- Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
HIV, Arterial Stiffness
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition.
- Conditions
- HIV, Arterial Stiffness, Cognitive Dysfunction
- Trial name
- NCT05965518
- Testing
- High-Intensity Interval Training, Continuous Moderate Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Ossification, Heterotopic
Celecoxib for Primary Prophylaxis of Combat-Related Heterotopic Ossification
Hypotheses: H1: Celecoxib, when given less than five days after injury will result in a statistical decrease in the incidence and/or severity of radiographically apparent Heterotopic Ossification when compared to controls.
- Trial name
- NCT01631669
- Testing
- Celecoxib
- Where
- 2 sites in United States, Germany
- Volunteers
- 100 people
- Sponsor
- Walter Reed National Military Medical Center
PTSD - Post Traumatic Stress Disorder, Insomnia
Suvorexant 3 - PE-PC
The goal of this clinical trial is to learn if combining suvorexant (a sleep medication) with a shorter form of prolonged exposure therapy called PE-PC works to treat PTSD symptoms and improve sleep in Veterans and military…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Insomnia, TBI (Traumatic Brain Injury)
- Trial name
- NCT07686731
- Testing
- Suvorexant, Prolonged Exposure Therapy for Primary Care (PE-PC)
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Northern California Institute of Research and Education