Clinical trials: Combat
Junctional Hemorrhage, Extremity Hemorrhage
Blind Vs US Guided Manual Pressure Points
the goal of this clinical trial is to compare the effectiveness of manual pressure points (femoral and supra-clavicular) for hemorrhage control by military medics using either the traditional blind manual technique or an…
- Trial name
- NCT06007209
- Testing
- Manual Pressure Point
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Pain, Neuroma
Comparative Evaluation of Intraneuroma and Perineuroma Botulinum Toxin Type A Injection Techniques for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Chronic Pain, Neuroma, Botulinium Toxin-A, Combat Trauma
- Trial name
- IN-PERI NEUROM (NCT07624877)
- Testing
- Botulinum toxin type A injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
PTSD - Post Traumatic Stress Disorder
Reported Experience Measurement on Reducing Patient Discomfort in Intensive Care
Hospitalisation in intensive care is always traumatic and can lead to a long rehabilitation process, slowed down by symptoms of anxiety and/or depression, and/or post-traumatic stress disorder (PTSD).
- Trial name
- PREMREA (NCT07525284)
- Testing
- PREMREA program
- Where
- France
- Volunteers
- 1,242 people
- Sponsor
- Almaviva Sante
Traumatic Brain Injury, Post-traumatic Stress Disorder
Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury
The scientific objective of this program is to meet the rehabilitation needs of combat wounded Veterans with mild to moderate Traumatic Brain Injury (TBI) via telerehabilitation and determine the effect of this modality of care…
- Trial name
- NCT00676182
- Testing
- Telerehabilitation
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
COVID 19 Vaccine
Combination Assessment Trial of COVID-19 Vaccines (COMBAT-COVID)
This is a randomized, phase II trial which will be conducted among volunteers aged 18 years and above in Karachi, Lahore and Islamabad, Pakistan. The trial will have nine arms and is an open label study.
- Trial name
- COMBAT-COVID (NCT05162482)
- Testing
- BIBP (CNBG, Sinopharm) WIV, CanSinoBIO, AstraZeneca ChAdOx
- Where
- 3 sites in Pakistan
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Overweight, Childhood
My Body is Fit and Fabulous at School Phase II
"My Body is Fit and Fabulous" (MyBFF@school) program was designed specifically for overweight and obese school children in order to help them control their BMI and body fat.
- Trial name
- NCT04155255
- Testing
- MyBFF@school
- Volunteers
- 2,438 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
PTSD - Post Traumatic Stress Disorder, Stress Disorder, Post Traumatic
Evaluation of the Effect of an Emergency Department Information Video on the Risk of Post-Traumatic Stress Disorder 30 Days After an Emergency Visit.
Post-traumatic stress disorder (PTSD) is a psychological disorder characterized by the re-experiencing of distressing symptoms, avoidance of traumatic memories and physiological hyperarousal in people who have been exposed to a…
- Trial name
- VISU (NCT06755606)
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-Traumatic Stress Disorder, PTSD, Alcohol Use Disorder (AUD)
Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974
Imaging PDE4B in people with psychiatric disorders with PET and the radiotracer [18F]PF974
- Trial name
- NCT07488819
- Testing
- PF974
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Yale University
Post Traumatic Stress Disorder
A Pilot Study of Deep Brain Stimulation of the Amygdala for Treatment-Refractory Combat Post-Traumatic Stress Disorder
The purpose of this study is to determine whether deep brain stimulation of the basolateral nucleus (BLn) of the amygdala, on both sides of the brain, can safely reduce symptoms of post-traumatic stress disorder (PTSD) in combat…
- Trial name
- ADIP (NCT01658748)
- Testing
- Week 0 Medtronic 3387 electrodes/Activa PC amygdala DBS, Week 12 Medtronic 3387 electrodes/Activa PC amygdala DBS
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
The Special Operations Care-Fund (SOC-F) will sponsor the application of four treatments - hormone replacement, magnetic resonance brain stimulation, ibogaine, and 5-Meo-DMT - to Special Operations Forces veterans with a history…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Trauma, Brain Injuries
- Trial name
- NCT06810765
- Testing
- Hormone Replacement Therapy (HRT), Magnetic Resonance Therapy (MeRT), ibogaine with magnesium treatment
- Where
- United States
- Sponsor
- Johns Hopkins University
Obesity
Can a Physical Activity Skill Development and Parent-Centered Dietary Intervention Help Combat Child Obesity?
The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health…
- Trial name
- NCT00107692
- Testing
- Physical activity and diet
- Where
- 2 sites in Australia
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Wollongong
PTSD - Post Traumatic Stress Disorder
Diet and Microbiome Interactions: Application in Posttraumatic Stress Disorder in Adults Consuming Vegetable Drinks
The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown that populations with more agrarian lifestyles tend to have fewer chronic diseases and mental health issues…
- Trial name
- DMAPS (NCT07107269)
- Testing
- Low diversity plant beverage (Functional Food Intervention), High diversity plant beverage (Functional Food Intervention)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Colorado State University
Post-Traumatic Stress Disorder, PTSD
Women Who Are Victims of Violence: Treatment of PTSD Through Reactivation of Traumatic Memories Using Propranolol
Post-traumatic stress disorder (PTSD) develops after life-threatening events, with domestic violence and sexual assault being major risk factors.
- Trial name
- VIOFEM (NCT07792122)
- Testing
- Propranolol, Psychotherapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Toulouse
Obesity, Hypertension
Postpartum Weight Retention
The Postpartum Weight Management Study is a true community-academic collaboration, bringing together Maternity Care Coalition (MCC) staff and the investigator, Dr.
- Conditions
- Obesity, Hypertension, Depression
- Trial name
- NCT02867631
- Testing
- 6 week challenge with 1 year of home visits: health texting, in home exercise supports, social support, healthy eating and feeding classes
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
PTSD - Post Traumatic Stress Disorder
Initial Study Sesting Efficacy and Tolerability of PT150 for PTSD in Veterans
The purpose of this study is to test the drug PT150, which blocks glucocorticoid receptor (GR) signaling, for treatment of PTSD in Veterans, and establish a safety and efficacy profile that will inform the design of future…
- Trial name
- NCT07187011
- Testing
- PT150
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- San Diego Veterans Healthcare System
Sarcopenia
Omega-3 Fatty Acids to Combat Sarcopenia
The purpose of this study is to determine how omega-3 fatty acids influence muscle protein metabolism and mitochondrial physiology in the context of human aging.
- Trial name
- NCT02103842
- Testing
- Omega-3 fatty acids
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Posttraumatic Stress Disorder
Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to conduct a randomized controlled trial to compare group and individual CPT-C for the treatment of PTSD in OIF/OEF military personnel.
- Trial name
- NCT02173561
- Testing
- Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Trauma
Dexamethasone as an Immediate Intervention
To determine if a single dose of dexamethasone (5 mg) administered in the first 12 hours following a potentially traumatic event alters a) cortisol and FKBP5 RNA the next day in the periphery measured in saliva; b) FKBP5…
- Trial name
- NCT02753166
- Testing
- Dexamethasone
- Where
- United States
- Sponsor
- NYU Langone Health
ST Elevation Acute Myocardial Infarction
COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial
Remote ischemic conditioning (RIC) and intravenous exenatide administered immediately before primary angioplasty have been found to limit infarct size in patients with STEMI (ST segment elevation myocardial infarction), but the…
- Trial name
- COMBAT-MI (NCT02404376)
- Testing
- Exenatide, Remote Ischemic Conditioning (RIC)
- Where
- 6 sites in Spain
- Volunteers
- 378 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute