Clinical trials: Communicable Disease
HIV Infections
Exploratory Study of Tipranavir and Ritonavir in Multiple Protease Inhibitor-experienced HIV Patients
The primary objective was to evaluate the antiviral activity and safety of two regimens of tipranavir (500 mg BID or 1000 mg BID) plus ritonavir (100 mg BID) administered in combination with 1 new nucleoside reverse transcriptase…
- Trial name
- NCT02238314
- Testing
- Tipranavir low dose, Tipranavir high dose, Ritonavir
- Volunteers
- 41 people
- Sponsor
- Boehringer Ingelheim
Cytomegalovirus Infection
Phase 1 Trial of CMV Towne Vaccine in Subjects Previously Received VCL CT02 Vaccine ID or IM
Objectives of this trial are to: 1. Evaluate the kinetics and magnitude of the CMV-specific immune response post-Towne challenge (3000 pfu) in healthy CMV-seronegative volunteers who received VCL CT02 administered ID or IM 9 to…
- Trial name
- NCT00370006
- Testing
- Towne CMV vaccine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Hepatitis B
Efficay of Extended Peginterferon Alpha 2a Treatment in HBeAg Negative Chronic Hepatitis B Patients
The most important method to slow down and stop the liver disease progression in patients with chronic hepatitis B is antiviral therapy, by which to achieve maintaining viral response during treatment or obtain sustained viral…
- Trial name
- NCT02387684
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Ditan Hospital
Ear Infection, Middle Ear Infection
Diagnostic Utility of Otosight Middle Ear Scope
Evaluate clinic workflow impact of OtoSight use for patients seen in the pediatric otolaryngology clinic.
- Conditions
- Ear Infection, Middle Ear Infection, Otitis Media
- Trial name
- NCT05641285
- Testing
- The OtoSight Middle Ear Scope
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Upper Respiratory Tract Infection, Lower Respiratory Infection
Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China
Main research purpose To investigate the pharmacokinetics of the test preparation azithromycin capsule and the reference preparation azithromycin capsule (Sumamed®) in Chinese healthy adult subjects by single oral administration…
- Conditions
- Upper Respiratory Tract Infection, Lower Respiratory Infection, Skin Infection, Subcutaneous Tissues Infection
- Trial name
- NCT06149117
- Testing
- test product (T) azithromycin capsule and reference product (R) azithromycin capsule "Sumamed®"
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Moderate COVID-19 Pneumonia, Severe COVID-19 Pneumonia, Pneumonia, Viral
COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients
Due to the limitations of COVID-19 treatment and in the absence of licensed antiviral for COVID-19, the historical choice of therapeutic convalescent plasma (CP) is considered especially against RNA viruses .It was known that…
- Trial name
- NCT04474340
- Testing
- COVID-19 Convalscent Plasma
- Where
- Kuwait
- Volunteers
- 300 people
- Sponsor
- Ministry of Health, Kuwait
Chronic Hepatitis B
Truvada Versus Truvada Plus Hepatitis B Immunoglobulin (HBIg) in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant
The objective of this 96-week study was to evaluate the safety and antiviral efficacy of emtricitabine/tenofovir disoproxil fumarate (FTC/TDF, coformulated; Truvada®) with or without hepatitis B immunoglobulin (HBIg) in…
- Trial name
- NCT00507689
- Testing
- FTC/TDF, Hepatitis B Immunoglobulin (HBIg)
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Gilead Sciences
Alcohol Dependence, HIV/AIDS
Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care
The proposed pilot study is a randomized feasibility trial of technology-enhanced brief intervention for drinking reduction and antiretroviral therapy (ART) adherence in 60 non-virally suppressed HIV participants who meet…
- Trial name
- NCT04280068
- Testing
- Clinician Guide (CG), Clinician Guide plus HealthCall
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Wound, Wound Infection
Evaluating Surface Area Reduction Using MolecuLight Imaging Device
12-week single-blind, prospective, randomized, controlled, pilot clinical trial assessing The MolecuLight i:X Imaging Device in chronic wounds.
- Trial name
- NCT03181568
- Testing
- MolecuLight i:X™ Imaging Device, Wound care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Calver Pang
HIV Infections
Acupuncture and Moxa: A Randomized Clinical Trial for Chronic Diarrhea in HIV Patients
The objective of this study is to test alternative treatment strategies to reduce the frequency of chronic diarrhea among HIV positive individuals. 60 percent of patients with HIV disease in the U.S.
- Trial name
- NCT00010491
- Testing
- Acupuncture, Moxibustion
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
HIV Infection
Integrase Resistance Analysis in HIV Patients Who Interrupted Raltegravir Due to Incomplete Viral Suppression
Prospective study to evaluate the potential persistent viral effect of raltegravir in 20 treatment experienced HIV patients with incomplete viral suppression
- Trial name
- RAL-dyn (NCT00787774)
- Testing
- resume raltegravir
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Clinic of Barcelona
HIV-1-infection
Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women
The goals of this clinical study are to learn more about the study drugs, VRC07-523LS, CAP256V2LS, and vesatolimod (VES) and how safe it is in women that have HIV and are on antiretroviral therapy (ART).
- Trial name
- NCT05281510
- Testing
- Vesatolimod, VRC07523LS, CAP256V2LS
- Where
- South Africa
- Volunteers
- 20 people
- Sponsor
- Gilead Sciences
Helicobacter Pylori Eradication Antibiotic
Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection
This study compared efficacy and safety of Ilaprazole based bismuth-containing quadruple regimen therapy including Ilaprazole 5mg, Bismuth Potassium Citrate 220mg, Clarithromycin 500mg and Amoxicillin Cap (Amoxicillin) 1000mg BID…
- Trial name
- NCT02835560
- Testing
- Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy, Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy
- Volunteers
- 100 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Cirrhosis Due to Hepatitis B
A Trial Comparing Entacavir and Tenofovir in Patients With HBV Decompensated Cirrhosis
Entacavir and tenofovir are two first line therapies for chronic hepatitis B. Both agents have been claimed equivalent in treatment, there are no head to head trials available in the literature about there effectiveness in HBV…
- Trial name
- NCT02238860
- Testing
- Entacavir, Tenofovir
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Asian Institute Of Medical Sciences
HIV Infections
A Multi-Center Randomized Double-Blind Placebo-Controlled Study To Investigate the Effect of Isoprinosine in Patients With AIDS Related Complex (ARC)
The objective is to determine the effect of Isoprinosine (inosine pranobex) in homosexual male patients with AIDS related complex (ARC) in delaying the onset of AIDS.
- Trial name
- NCT00002060
- Testing
- Inosine pranobex
- Where
- United States
- Sponsor
- Newport Pharmaceuticals International
Hepatitis B
Hepatitis B Seroepidemiology Among Young Adults
Taiwan has launched a successful nationwide neonatal hepatitis B immunization since July 1, 1984. It successfully decreased the incidence of hepatitis B virus infection, the hepatitis B carrier rate as well as liver diseases…
- Trial name
- NCT01973582
- Where
- Taiwan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HIV Infections, HIV Seronegativity
Daily Tenofovir DF to Prevent HIV Infection Among Sex Workers in Cambodia
Tenofovir disoproxil fumarate (also known as tenofovir DF or Viread) is used with other anti-HIV drugs to treat HIV infection. Taking tenofovir DF every day may also prevent HIV infection.
- Trial name
- NCT00078182
- Testing
- Tenofovir DF
- Where
- Cambodia
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Open Fracture, Pseudarthrosis
Septic Management and Outcome of Open Fracture
The aim is the study of the management and outcome of the open fractures. Some open fractures will become pseudarthrosis. Thoses pseudarthrosis may be septic or not.
- Conditions
- Open Fracture, Pseudarthrosis, Bone and Joint Infection
- Trial name
- NCT04418882
- Testing
- management and follow up of all open fractures
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Antibiotic Resistant Infection
Effectiveness of Chlorhexidine Wipe for Prevention of Multidrug-resistant Organisms in Intensive Care Unit Patients
The purpose of this study is to determine 2% chlorhexidine wipes are effective in preventing of colonization of multi-drug resistant bacteria in intensive care unit patients.
- Trial name
- NCT01989416
- Testing
- 2% chlorhexidine wipe, Soap
- Where
- Thailand
- Volunteers
- 481 people
- Sponsor
- Mahidol University
Frail Elderly, Clostridioides Difficile
Clostridioides Difficile and Frailty
CDI is a major cause of antibiotics-associated diarrhoea. More than half of the patients affected are 70 years or older and frail. Mortality among older patients with CDI is high.
- Conditions
- Frail Elderly, Clostridioides Difficile, Geriatric Assessment, Faecal Microbiota Transplantation
- Trial name
- CLODIFRAIL (NCT05447533)
- Testing
- Comprehensive geriatric assessment (CGA), Continued geriatric care, Faecal microbiota transplantation (FMT)
- Where
- Denmark
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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