Clinical trials: Community Pneumonia
Community Acquired Pneumonia
Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Pneumonia and Pneumococcal Vaccine
The aim of this study is to test if BPS (Bacterial Pneumonia Score) guided antibiotic use in children with non severe community acquired pneumonia (CAP) and pneumoccocal vaccine will reduce antibiotic use as compared to standard…
- Trial name
- NCT01875731
- Testing
- BPS, Guideline
- Where
- Argentina
- Volunteers
- 66 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Pneumonia
Vitamin D Supplementation and Respiratory Index of Severity in Children (RISC) in Pneumonia
Childhood deaths from pneumonia is almost 2000 times higher in developing countries than in developed countries. In 1970, pneumonia was responsible for 9% of all deaths in children under 5 years. This rate was 2% in 2007.
- Trial name
- NCT02936895
- Testing
- Vitamin D3
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Community-acquired Pneumonia
Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia.
The goal of this clinical trial is to compare the safety and efficacy of AON-D21 versus placebo, both on top of standard of care, in patients with severe community acquired pneumonia admitted to ICU (or similar unit).
- Trial name
- NCT05962606
- Testing
- AON-D21
- Where
- 27 sites in United States, Belgium and 4 more
- Volunteers
- 150 people
- Sponsor
- Aptarion Biotech AG
Infections, Community Acquired Pneumonia
Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)
This is a study of safety and effectiveness of ceftaroline fosamil in children with Community Acquired Bacterial Pneumonia receiving antibiotic therapy in the hospital.
- Trial name
- NCT01530763
- Testing
- Ceftaroline fosamil, Ceftriaxone, amoxicillin clavulanate
- Where
- 44 sites in United States, Argentina and 7 more
- Volunteers
- 161 people
- Sponsor
- Forest Laboratories
Bacterial Infection, Sepsis
Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
Approximately one-third of neonatal deaths in developing countries are due to infections acquired through the birth canal and/or exposure to an unclean environment soon after birth.
- Conditions
- Bacterial Infection, Sepsis, Infant, Newborn
- Trial name
- NCT00189384
- Testing
- ceftriaxone, procaine penicillin and gentamicin, oral cotrimoxazole and gentamicin
- Where
- Pakistan
- Volunteers
- 426 people
- Sponsor
- Aga Khan University
Community-acquired Pneumonia
Oral Nemonoxacin in Treating Elderly Patients With CAP
This study was to evaluate the safety and efficacy of oral nemonoxacin in treating elderly patients (aged ≥ 65 years) with community-acquired pneumonia (CAP).
- Trial name
- NCT05133752
- Testing
- Nemonoxacin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- TaiGen Biotechnology Co., Ltd.
Community-acquired Pneumonia, Acute Otitis Media
Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions
The main goal of this study is to use automated electronic reports to assess and improve guideline-concordant antibiotic use for: 1) adult inpatients with community-acquired pneumonia; 2) pediatric inpatients with…
- Conditions
- Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
- Trial name
- EMPOWER (NCT06027593)
- Testing
- Quasi experimental intervention
- Where
- 2 sites in United States
- Volunteers
- 26,139 people
- Sponsor
- Children's Hospital of Philadelphia
Community-Acquired Pneumonia, Vitamin a
The Effect of Adjunct Vitamin a on Community-Acquired Pneumonia in Southern Iranian Children: a Randomized Clinical Trial
This randomized clinical trial included 105 children with CAP who were admitted to Bandar Abbas Children's Hospital. Participants were randomly assigned to two groups: a control group receiving standard antibiotic therapy and an…
- Trial name
- CAP Vitamin A (NCT06677684)
- Testing
- Vitamin A
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
COVID-19 Testing Behaviors
Examining How a Text Message-based Educational Intervention Influences COVID-19 Testing
In this Phase III study, the investigators will build off of the Phase II embedded study with some adjustments to the design to address new research priorities that examine an intervention that is network informed and delivered…
- Trial name
- NCT07074171
- Testing
- Text message-based education intervention, Historical Control
- Where
- 3 sites in United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Community-acquired Pneumonia
Comparison of Efficacy of Oral Amoxicillin Versus Intravenous Ceftriaxone
The efficacy of oral amoxicillin is considered equal to that of ceftriaxone in community-acquired pneumonia among children. Also, there are some factors that contradict the usage of ceftriaxone, like antibiotic resistance…
- Trial name
- NCT06532409
- Testing
- Amoxicillin/CA, IV ceftriaxone
- Where
- Pakistan
- Volunteers
- 114 people
- Sponsor
- RESnTEC, Institute of Research
Covid19, Mental Health Issue
CRISOL Contigo: a Multi-level Intervention to Reduce the Disproportionate Toll of COVID-19 Among Latino Communities in Philadelphia.
Latinos have been one of the racial/ethnic groups most impacted by the COVID-19 pandemic, and evidence of effective strategies to curb the pandemic, reduce disparities, and mitigate its impact is lacking and very urgent.
- Conditions
- Covid19, Mental Health Issue, Violence
- Trial name
- CRISOL Contigo (NCT04646616)
- Testing
- Community popular opinion leader (POL) based intervention
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Drexel University
Community Acquired Pneumonia
Evaluation the Clinical Value of Xiyanping Injection in the Treatment of Community-acquired Pneumonia in Children
In order to verify the clinical value and safety of Xiyanping injection in children with CAP, we intend to carry out this multi-center, large-sample, non-intervention clinical research through more rigorous and scientific design.
- Trial name
- NCT04158310
- Volunteers
- 9,207 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Activities, Mental Health Issue
Effects of the COVID-19 Health Emergency on Biopsychosocial Health
There is a critical need to determine the impact of the COVID-19 emergency on the comprehensive well-being of people as they are living through the emergency and sequelae of the emergency period.
- Conditions
- Activities, Mental Health Issue, Life Style
- Trial name
- NCT04409535
- Testing
- WHOQOL-BREF survey
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Covid19
SCALE-UP Utah: Community-Academic Partnership to Address COVID-19 Testing Among Utah Community Health Centers
SCALE-UP Utah is a community-academic partnership to address COVID-19 among Utah community health centers. The long-term objective of the project is to increase the reach, acceptance, uptake, and long-term sustainability of…
- Trial name
- NCT04939532
- Testing
- Text-Messaging (TM), Patient Navigation (PN)
- Where
- United States
- Volunteers
- 44,729 people, healthy volunteers welcome
- Sponsor
- University of Utah
Severe Community-acquired Pneumonia (sCAP)
Randomized Adaptive Platform Trial of Pathogen-Directed Anti-inflammatory Therapy in Severe Community-Acquired Pneumonia(Core Protocal)
Severe community-acquired pneumonia (sCAP) has a high mortality rate of 25-50%. Excessive host inflammatory responses contribute to poor outcomes.
- Trial name
- PANDA-SCAP (NCT07152587)
- Testing
- Low dose steroids, Moderate dose steroids, Saline (0.9% NaCl)
- Volunteers
- 1,500 people
- Sponsor
- Qingyuan Zhan
Pneumonia
Zithromax EV in Community-Acquired Pneumonia (CAP)
The intravenous (IV) regimen containing azithromycin (Zithromax) plus ampicillin-sulbactam is consistent with current guidelines for the treatment of CAP.
- Trial name
- NCT00137007
- Testing
- Azithromycin, Ampicillin/sulbactam
- Volunteers
- 151 people
- Sponsor
- Pfizer
Community-dwelling Older Adults
Impact of Balance Training in Community-Dwelling Older Adults After Recovery From COVID-19
This research investigates the impact of balance training on improving functional performance and reducing fall risk in community-dwelling older adults who have recovered from COVID-19.
- Trial name
- NCT07002736
- Testing
- The Biodex training, Traditional balance training
- Where
- Saudi Arabia
- Volunteers
- 65 people
- Sponsor
- Cairo University
Pneumonia
CAPRIVI: Community Acquired Pneumonia: Treatment With Avelox® in Hospitalized Patients
The aim of this study is to obtain data from hospitalized Community Acquired Pneumonia (CAP) patients on the disease including disease severity, clinical signs and symptoms and measures used for diagnosis in daily routine…
- Trial name
- NCT00987792
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 11 sites in Croatia, France and 9 more
- Volunteers
- 2,595 people
- Sponsor
- Bayer
Sepsis, Septic Shock
Pharmacokinetics of XueBiJing in Patients With Sepsis
Pharmacokinetics and disposition of XueBiJing compounds in patients with sepsis
- Conditions
- Sepsis, Septic Shock, Community Acquired Pneumonia
- Trial name
- NCT03475732
- Testing
- XueBiJing injection
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Southeast University, China
Respiratory Distress Syndrome, Acute, Severe Community-Acquired Pneumonia
Multimodal Database and Large Language Model for ARDS
The goal of this observational study is to integrate existing clinical cohorts from the research team to establish dedicated cohorts for ARDS and high-risk ARDS patients (primarily SCAP patients), then systematically collect…
- Trial name
- NCT06973733
- Testing
- Clinical data and biospecimen collection
- Volunteers
- 6,500 people
- Sponsor
- China-Japan Friendship Hospital