Clinical trials: Community Pneumonia
Pneumonia Childhood
Improving CarE for Community Acquired Pneumonia 1 (ICE-CAP2)
Children with pneumonia presenting to the emergency department at Monroe Carell Jr. Children's Hospital at Vanderbilt or Children's Hospital of Pittsburgh will be potentially eligible for study.
- Trial name
- ICE-CAP2 (NCT06033079)
- Testing
- Clinical Decision Support
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- Vanderbilt University Medical Center
Covid19
Leveraging CHWs to Improve COVID-19 Testing and Mitigation Among CJIs Accessing a Corrections-focused CBO
Given the likelihood of COVID-19 remaining an endemic disease among high-risk populations, establishing effective mitigation interventions will be critical to stemming community transmission.
- Trial name
- NCT04878328
- Testing
- Onsite Point-of-care
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Montefiore Medical Center
Respiratory Tract Infections
Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine
To describe the relief of symptoms, tolerability, and compliance of treatment with Klacid® sustained release (SR) at a dose of 1000 mg once daily in patients with acute tracheitis, acute tracheobronchitis, acute bronchitis, or in…
- Trial name
- KLARAINE (NCT01095978)
- Testing
- Clarithromycin (Klacid SR)
- Where
- 126 sites in Ukraine
- Volunteers
- 2,822 people
- Sponsor
- Abbott
Pneumonia, Bacterial
A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization
The purpose of this study is to test if intravenous sulopenem and an oral drug, PF-03709270 are safe and effective in patients that are hospitalized with community acquired pneumonia.
- Trial name
- NCT00797108
- Testing
- sulopenem and PF-03709270, Ceftriaxone and amoxicillin/clavulanate
- Where
- 24 sites in United States, Australia and 3 more
- Volunteers
- 35 people
- Sponsor
- Pfizer
Covid19
Test to Stay in School: COVID-19 Testing Following Exposure in School Communities
Participants in school communities who have been exposed to SARS-CoV-2 will be tested for COVID-19 on the day of exposure (day 1) and at days 3, 5, and 7 following initial known exposure.
- Trial name
- NCT05052580
- Testing
- COVID-19 Testing
- Where
- United States
- Volunteers
- 4,733 people
- Sponsor
- Duke University
Bacterial Pneumonia
Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of Community-Acquired Pneumonia
- Trial name
- CAP (NCT00621504)
- Testing
- Ceftaroline fosamil for Injection, IV Ceftriaxone, Clarithromycin
- Where
- 168 sites in United States, Argentina and 21 more
- Volunteers
- 606 people
- Sponsor
- Forest Laboratories
Pneumonia
Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Community Acquired Pneumonia
The aim of this study is to test if BPS (Bacterial Pneumonia Score) guided antibiotic use in children with non severe community acquired pneumonia (CAP) will reduce antibiotic use as compared to standard care practice (current…
- Trial name
- NCT01041209
- Testing
- Strategy based on BPS guided antibiotic use, Enforced Guidelines
- Where
- Argentina
- Volunteers
- 120 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
COVID-19
RADx-UP CDCC Rapid Research Pilot Program "Culturally-relevant Community Connections (C3) to Increase COVID-19 Testing
The purpose of this study is to identify barriers and facilitators to COVID testing among members of the Black/African American community.
- Trial name
- NCT05918952
- Testing
- Covid-19 Antibody Test, Short Clip videos
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Duke University
Pneumonia, Malaria
Zambia Integrated Management of Malaria and Pneumonia Study
The purpose of the study is to demonstrate the effectiveness and feasibility of community-based management of pneumonia and malaria by community health workers (CHWs) in a rural district of Zambia.
- Trial name
- ZIMMAPS (NCT00513500)
- Testing
- Coartem and amoxicillin, Coartem
- Where
- Zambia
- Volunteers
- 3,125 people
- Sponsor
- Boston University
Covid19, SARS-CoV2 Infection
Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
The primary aim of the proposed research is to test the role of a newly developed reusable form-fitting fabric mask in reducing the spread of COVID-19 in a community setting comprising undergraduate students living in dormitories…
- Trial name
- NCT04979858
- Testing
- Focal Mask
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Health Behavior, Health Care Utilization
COVID-19: Healthy Oregon (Oregon Saludable): Together We Can (Juntos Podemos) Phase II
The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis that the United States has faced in a century.
- Trial name
- OSJP (NCT05082935)
- Testing
- Phase II Promotores de Salud, Phase I Promotores de Salud Outreach
- Where
- United States
- Volunteers
- 1,463 people
- Sponsor
- University of Oregon
Community-acquired Pneumonia (CAP), Hospital-acquired Pneumonia (HAP)
Ceftobiprole in the Treatment of Pediatric Patients With Pneumonia
This was a study of the safety and efficacy of ceftobiprole medocaril compared with intravenous (IV) standard-of-care cephalosporin treatment with or without vancomycin in pediatric patients with either hospital-acquired…
- Trial name
- NCT03439124
- Testing
- ceftobiprole medocaril, IV standard-of-care cephalosporin
- Where
- 19 sites in Bulgaria, Georgia and 2 more
- Volunteers
- 138 people
- Sponsor
- Basilea Pharmaceutica
Pneumonia, Bacterial, Community-Acquired Infections
A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia
The purpose of this study is to evaluate the safety and tolerability of doripenem compared to cefepime in children hospitalized with pneumonia.
- Conditions
- Pneumonia, Bacterial, Community-Acquired Infections, Nosocomial Infection, Pneumonia, Ventilator-Associated
- Trial name
- NCT01110421
- Testing
- Cefepime, Doripenem, Amoxicillin/clavulanate potassium
- Where
- 25 sites in United States, Argentina and 8 more
- Volunteers
- 7 people
- Sponsor
- Janssen Research & Development, LLC
Bacterial Pneumonia
Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia
The purpose of the study is to determine if the antibiotic ceftaroline is safe and effective in the treatment of community-acquired pneumonia in adults.
- Trial name
- CAP (NCT00509106)
- Testing
- Ceftaroline fosamil for Injection, Ceftriaxone
- Where
- 134 sites in United States, Argentina and 13 more
- Volunteers
- 622 people
- Sponsor
- Forest Laboratories
Covid19
Evaluation of the INDICAID™ COVID-19 Rapid Antigen Test
The INDICAID™ Rapid Antigen Test was used in real-world outbreak testing. The antigen test was used together with PCR testing. This study was designed to evaluate whether the addition of a rapid antigen test decreased time to…
- Trial name
- NCT04904510
- Testing
- INDICAID™ COVID-19 Rapid Antigen Test
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Community-acquired Pneumonia, Bacterial Pneumonia
Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia
The purpose of this study is to evaluate the safety and efficacy of omadacycline as compared to moxifloxacin in the treatment of adults with community-acquired bacterial pneumonia.
- Trial name
- NCT04779242
- Testing
- Omadacycline, Moxifloxacin
- Where
- 55 sites in Bulgaria, Croatia and 6 more
- Volunteers
- 670 people
- Sponsor
- Paratek Pharmaceuticals Inc
Community-Acquired Pneumonia
Non-Interventional Open Label Prospective Observational Comparative Study On Evaluation Of Compliance Of The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Mild To Moderate Community Acquired Pneumonia
To compare compliance between patients with CAP treated with Azithromycin SR 2.0 g single dose orally and those treated with Amoxiclav - 1000 mg twice daily 10 days for the empiric treatment of CAP in outpatient clinic practice.
- Trial name
- PROSTO (NCT01032694)
- Testing
- Azithromycin SR, Amoxiclav
- Volunteers
- 30 people
- Sponsor
- Pfizer
Covid19
Covid-19 Messaging to Underserved Communities - 2nd Experiment
The aim of the study is to build off results from our first experiment (NCT04371419) , and test whether messages that acknowledge racial injustice on behalf of institutions affect the retention of knowledge and movement of…
- Trial name
- NCT04502056
- Testing
- Acknowledgement Racial Injustice AMA, African American Sender Acknowledgement, African American Sender in Informational Videos.
- Where
- United States
- Volunteers
- 20,460 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Pneumonia, Bacterial
Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia
The primary objective of this study was to evaluate the clinical efficacy of treatment with Nemonoxacin compared with Tavanic® in patients with community-acquired pneumonia (CAP).
- Trial name
- NCT03551210
- Testing
- Nemonoxacin, Tavanic
- Where
- 25 sites in Russia
- Volunteers
- 342 people
- Sponsor
- R-Pharm
Coccidioidomycosis
Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)
This is a Phase IV randomized, double-blinded, placebo-controlled study in 1000 individuals aged 18 years or older, with community acquired pneumonia (CAP) who meet all eligibility criteria in endemic regions.
- Trial name
- NCT02663674
- Testing
- Fluconazole
- Where
- 9 sites in United States
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)