Clinical trials: Community-based
Social Isolation in Older Adults, Loneliness
Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health
This study evaluates the effectiveness of a community-based social connection intervention program (SCIP) designed to reduce social isolation and loneliness and improve cardiovascular and brain health among older adults living in…
- Conditions
- Social Isolation in Older Adults, Loneliness, Stroke, Cognitive Decline
- Trial name
- NCT07319663
- Testing
- Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness.
- Where
- Ecuador
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Behavior, Child, Neurocognition, Child
Community-Based Conscious Discipline Program in Grenada
To improve neurocognitive outcomes in 2-year-old children by implementing a community-based intervention program that follows the principles of Conscious Discipline.
- Conditions
- Behavior, Child, Neurocognition, Child, Development, Child
- Trial name
- NCT04697134
- Testing
- Conscious Discipline-Based Environmental Enrichment Intervention
- Where
- Grenada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Windward Islands Research and Education Foundation
Colorectal Cancer
A Prospective Cohort Study on Colorectal Cancer Screening in Community Population
This study will validate the real world results of polygene methylation detection in colorectal cancer in a large prospective community cohort.
- Trial name
- NCT05485077
- Where
- China
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
HIV Infections, Preexposure Prophylaxis (PrEP)
Clinical Decision Support for PrEP
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the federal initiative to end the HIV epidemic. However, healthcare providers lack tools to identify patients who are at increased risk for HIV infection and…
- Trial name
- PrEDICT (NCT05245201)
- Testing
- Standard of care, Clinical decision support for PrEP
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Alzheimer's Disease
A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology
The primary purpose of this study is to identify participants with or without symptoms of Alzheimer's Disease (AD) that are at high risk for brain amyloid pathology using blood-based biomarkers.
- Trial name
- NCT06043700
- Testing
- No Intervention
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Eisai Limited
Spinal Cord Injuries, Rehabilitation
Study on Rehabilitation Exercise Program for Community-based Spinal Cord Injury Patients
In the case of spinal cord injury, patients have shown a passive attitude towards participating in leisure sports or exercise programs, and there is a lack of suitable guidelines or experience in the local community for coaching…
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercise Program
- Trial name
- NCT05878145
- Testing
- Structured rehabilitation exercise program
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Autism
Centering Autistic Perspectives in Behavioral Intervention Discussions
The Centering Autistic Perspectives for Behavioral Interventions Discussions (CAPBID) PCORI Science of Engagement Award will examine different community engagement approaches for bringing together autistic people, Applied…
- Trial name
- CAPBID SoE (NCT07165522)
- Testing
- Transformative and Restorative Engagement Circle (TREC), Stakeholder Engagement in quEstion Development and prioritization (SEED)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Drexel University
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Developmental Delay
School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays
This proposal aims to test whether a proposed community-clinical linkage (CCL), an educational-medical linkage model, improves access to school-based services and subsequent child, parent, family and health service outcomes and…
- Trial name
- PreM (NCT06145659)
- Testing
- Preschool and Me
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV Infections
Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe
The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in…
- Trial name
- NCT00390949
- Testing
- Peer education among commercial sex workers and clients, Condom distribution and promotion, Syndromic treatment of sexually transmitted infections
- Where
- Zimbabwe
- Volunteers
- 9,454 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Mental Health Issue, Substance Use
Mental Health, Gender-Based Violence, and Stunting in Tanzania
One in three children under the age of five in Tanzania experience stunting, which is defined as impairments in growth and development that often occur after poor nutrition, poor health, and low psychosocial stimulation.
- Conditions
- Mental Health Issue, Substance Use, Child Development
- Trial name
- NCT06065293
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Hepatitis C, Chronic
Direct-acting Antiviral Therapy and Reinfection Among PWID With Chronic HCV in Community-based Settings
SHARP-C is an observational cohort study investigating the effect of direct-acting antiviral (DAA) therapy and reinfection in people with chronic hepatitis C virus (HCV) and recent injecting drug use.
- Trial name
- SHARP-C (NCT03343925)
- Where
- 4 sites in Australia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Obesity, Overweight
Koa Family Study--A Community-Based Intervention to Improve Health and Well-Being
Wholehearted living touches every aspect of life, from eating nourishing foods, to enjoying enough physical activity, to cultivating relationships that support healthy choices, to joining with neighbors to stand up for positive…
- Conditions
- Obesity, Overweight, Diet, Healthy, Social Interaction
- Trial name
- KFS (NCT04662593)
- Testing
- Whole Health Program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pandemics
Conversational Agent Vaccine Promotion RCT
The objective of this study is to assess the use of and satisfaction with the ECA intervention over a 12-month period, its ability to increase SARS-CoV-2 and influenza vaccination in the BMATP community, and the comparative…
- Trial name
- NCT04884750
- Testing
- ECA-ACE Vaccination Promotion Intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Depression, Anxiety
Virtual Mindfulness Intervention RCT
Mindfulness-based interventions (MBIs) have emerged as clinically effective interventions for anxiety, depression, and general distress.
- Trial name
- NCT05374213
- Testing
- Mindfulness-Based Intervention
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Loneliness
Testing a Nature-based Social Intervention on Loneliness: the RECETAS-BCN Trial
RECETAS (Re-imagining Environments for Connection and Engagement: Testing Actions for Social Prescribing in Natural Spaces) is an European project (H2020 No 945095) that aims to reduce loneliness by linking lonely people to…
- Trial name
- RECETAS-BCN (NCT05488496)
- Testing
- Nature-based social intervention (NBSI), referred as Friends in Nature (FiN), Usual care + menu with nature-based activities
- Where
- Spain
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension
Community Vital Signs (CVS): An Integrated Community-Based Approach to Identify Undiagnosed Hypertension in Nigeria
If detected early, hypertension (HTN) is treatable; yet, HTN screening rates are low and inequitable in Sub-Saharan Africa (SSA) leaving many people with undiagnosed HTN, especially in urban areas.
- Trial name
- NCT06659900
- Testing
- CORE Plus (+), CORE
- Where
- Nigeria
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Alzheimer Disease, Dementia
MEMORI Corps: Activity-based Companion Care for Dementia
This project adapts a novel activity-based companion care model, the Making Engagement Meaningful through Organized Routine Interaction (MEMORI) Corps intervention, for a virtual delivery format, and then implements the…
- Trial name
- MEMORI Corps (NCT03896711)
- Testing
- MEMORI Corps program, Augmented Waitlist Control
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV Infections
Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT
The goal of this hybrid (1a) Cluster Randomised Controlled Trial phase 3B trial is to evaluate the effectiveness and implementation of offering a choice of HIV Pre-Exposure Products (PrEP) through community-based sexual and…
- Trial name
- LAPIS (NCT06250504)
- Testing
- APRETUDE (cabotegravir) 600 mg\3 mL, DAPIRING (Dapivirine) 25mg Vaginal Ring, tenofovir disoproxil and emtricitabine
- Where
- South Africa
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute