Clinical trials: Community-based
Substance Use, Substance-Related Disorders
Clinician Practice Companion to Address Youth Substance Use
Substance use, including the use of opioids, cannabis, and other drugs, is common among adolescents and young adults, and overdose has become a leading cause of death among youth in Canada and the United States.
- Conditions
- Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use
- Trial name
- NCT07725289
- Testing
- Practice Companion
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Self-concept, Psychological Adjustment
Community Galleries - Art and Children in Action: Study Protocol
The goal of this trial is to evaluate whether a community-based visual arts intervention can improve self-concept, psychological adjustment, and health-related quality of life (HRQoL) in children aged between 6 and 12, from…
- Conditions
- Self-concept, Psychological Adjustment, Health Related Quality of Life
- Trial name
- NCT07165704
- Testing
- Visual arts
- Where
- 10 sites in Portugal
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Associação para o Apoio à Integração Social e Comunitária
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Cardiometabolic Disease
Building Access to Food Through Systems and Solidarity (BASIS): A Subsidized and Culturally-adapted Produce Box Program for Immigrant Communities of Brooklyn, NY
The goal of this study is to improve diet and social cohesion among Chinese American families living in New York City (NYC) through a program that provides whole grains and legumes, builds ethnic identity, and fosters family…
- Trial name
- NCT07076251
- Testing
- Family Box program
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Cancer, Rectal Cancer
PeLear CCC: Proyecto Latino Contra Cancer Colorrectal
The study aims to recruit 60 Spanish speaking individuals who identify as Latinos, are 18 years or older and attend the Saint Thomas More (STM) Church in Chapel Hill.
- Conditions
- Colorectal Cancer, Rectal Cancer, Colon Cancer, Colon Rectal Cancer
- Trial name
- PeLear CCC (NCT06426927)
- Testing
- Colorectal Cancer Educational Videos in Spanish
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
People Who Inject Drugs
Evaluation of an Educational Intervention on Abscesses in People Who Self-inject Drugs
The goal of this cluster randomised controlled trial (cRCT) is to to evaluate the effectiveness of an educational intervention combining training in hand-washing with the supply of MONO-RUBs on the reduction of skin abscesses…
- Trial name
- HAWA (NCT06131788)
- Testing
- Educational hand hygiene intervention
- Where
- 22 sites in France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pneumonia
A Study on Pathogenic Surveillance and Nasopharyngeal Carriage of Children and Adolescents Based on Hospitals and Communities in Hainan Province
This study intends to screen children under the age of 10 for respiratory pathogens, Streptococcus pneumoniae, and serotyping in three representative cities in Hainan province: Haikou, Wanning, and Baisha, in order to provide a…
- Trial name
- NCT05912010
- Testing
- NP/OP swab
- Where
- 5 sites in China
- Volunteers
- 3,746 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Diabetes Mellitus, Hyperglycaemia (Diabetic)
Validation of Remote Photoplethysmography for Non-Invasive Estimation of Blood Glucose and HbA1c
The goal of this observational study is to evaluate whether a non-invasive facial scan technology using remote photoplethysmography (rPPG) can accurately estimate blood glucose and HbA1c levels in adults living in the community…
- Conditions
- Diabetes Mellitus, Hyperglycaemia (Diabetic), Hyperglycaemia (Non Diabetic), Hypoglycaemia
- Trial name
- NCT07502690
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Community-Based Participatory Research, Adolescent Behavior
My Best Alaskan Life: A Community-Designed Intervention to Improve Youth/Young Adults' Sexual and Mental Health
This project addresses critical public health disparities among Alaskan youth and young adults by developing and evaluating "My Best Alaskan Life" (MBAL), an innovative online tool aimed at improving sexual and mental health…
- Conditions
- Community-Based Participatory Research, Adolescent Behavior, Mental Depression, Sexual Health
- Trial name
- MBAL (NCT06482242)
- Testing
- My Best Alaska Life
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Papillomavirus Vaccines, HPV Vaccines
HPV Vaccine Integrated Service Implementation Research in Ethiopia
The goal of this implementation research study is to understand whether a package of community-based interventions can increase access to and uptake of the human papillomavirus (HPV) vaccine among very young adolescent girls in…
- Conditions
- Papillomavirus Vaccines, HPV Vaccines, HPV Vaccine Acceptability, HPV Vaccine Attitudes
- Trial name
- HPV-VISION (NCT06667323)
- Testing
- Integrated health service delivery for very young adolescent girls
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- Population Services International
Social Cognition, Healthy Aging
Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effects of an immersive virtual reality (VR)-based group dance program on perceived social cohesion among community-dwelling older adults…
- Conditions
- Social Cognition, Healthy Aging, Loneliness, Social Isolation
- Trial name
- VR-GD-COHESION (NCT07850479)
- Testing
- Immersive VR Group Dance Program, Conventional Light Physical Activity Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Diarrhea, Stunting
Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth
This is a randomized, double-blind, community-based efficacy trial of different doses, forms, and frequencies of zinc supplementation for the prevention of diarrhea and promotion of linear growth among children 9-11 months of age…
- Trial name
- NCT03406793
- Testing
- Standard MNP, High zinc, low iron MNP, High zinc, low/no iron on alternating days
- Where
- Bangladesh
- Volunteers
- 2,886 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Hepatitis C, Chronic
Direct-acting Antiviral Therapy and Reinfection Among PWID With Chronic HCV in Community-based Settings
SHARP-C is an observational cohort study investigating the effect of direct-acting antiviral (DAA) therapy and reinfection in people with chronic hepatitis C virus (HCV) and recent injecting drug use.
- Trial name
- SHARP-C (NCT03343925)
- Where
- 4 sites in Australia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Heart Disease, Diabetes
Fruits, Vegetables, and Whole Grains: A Community-based Intervention
The aim of this study is to see if the investigators can encourage people to eat more fruits, vegetables and whole grains and drink less pop by giving them advice about their diet, or by providing them with samples of different…
- Conditions
- Heart Disease, Diabetes, Hypertension
- Trial name
- NCT00516620
- Testing
- No further instruction, Food Delivery, Fruits (F), vegetables (V), and whole grain (WG) counseling
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension
A Cluster-Randomized Trial of a Hypertension Risk Model-Based Precision Intervention in High-Risk Adults in Shunyi District
This community cluster-randomized controlled trial aims to evaluate the effectiveness of a hypertension risk model-based precision intervention among adults at high risk of developing hypertension in Shunyi District, Beijing…
- Trial name
- NCT07804420
- Testing
- Hypertension Risk Model-Based Precision Intervention, Standard Health Education
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University
Depression
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral \& Interpersonal…
- Trial name
- P2P (NCT04290754)
- Testing
- CATCH-IT, TEAMS
- Where
- United States
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV CDC Category A1
A Community-based Implementation Model for HIV Prevention and Testing in Malawi
This implementation study is testing whether community members can use a 3-step model (prepare, roll-out and sustain) to implement an efficacious peer group HIV prevention intervention with fidelity and effectiveness in a single…
- Trial name
- NCT02765659
- Testing
- Mzake ndi Mzake T1, Mzake ndi Mzake T2, Mzake ndi Mzake T3
- Where
- Malawi
- Volunteers
- 1,353 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Intervention in Hand Hygiene for Infectious Diseases Prevention
Impact of an AI-enabled UV Hand Hygiene Intervention in Primary Schools: a Community Intervention Study
Background Hand hygiene refers to the practice of keeping hands clean to prevent the spread of disease. Hand hygiene workshops are an important tool to educate students about the importance of keeping their hands clean and…
- Trial name
- NCT07160842
- Testing
- Hand hygiene intervention
- Where
- Spain
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Institut Catala de Salut
Depression, Anxiety
Virtual Mindfulness Intervention RCT
Mindfulness-based interventions (MBIs) have emerged as clinically effective interventions for anxiety, depression, and general distress.
- Trial name
- NCT05374213
- Testing
- Mindfulness-Based Intervention
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Health Promotion
SHE Tribe: An Intervention to Improve Health Behavior Among Women in Underserved Communities
While healthy lifestyle behaviors have been identified as instrumental to preventing chronic disease, programs to successfully promote healthy behavior adoption in underserved communities have had limited sustainable success.
- Trial name
- NCT03463213
- Testing
- SHE Tribe
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center