Clinical trials: Community-based
Obesity
The Effectiveness of Commercial Weight Loss Programmes
The objective is to compare the effectiveness of 4 different commercial weight-loss diets available to adults in the UK. This is achieved with a 6 month multi-centre randomised unblinded controlled trial of Dr Atkins' New Diet…
- Trial name
- NCT00327821
- Testing
- calorie controlled diet
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Training of Mental Health Professionals, Training of Frontline Health Workers
Measurement-Based Peer Supervision App for Non-Specialist Providers
The goal of this project is to enhance and evaluate the efficacy of a scalable digital solution designed to help train and support the work of non-specialist providers (NSPs), such as community health workers, to deliver therapy…
- Trial name
- NCT07082010
- Testing
- MBPS App
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Dimagi Inc.
Maternal Death
Reducing Racial Disparities in Severe Maternal Morbidity
There is a paucity of research examining the intersection of race, ethnicity, maternal safety bundles, doulas, and maternal outcomes in Black women at increased risk of severe maternal morbidity and mortality.
- Trial name
- NCT04879797
- Testing
- Implementation of Maternal Safety Bundles, Doula Services
- Where
- United States
- Volunteers
- 1,538 people, healthy volunteers welcome
- Sponsor
- Tufts University
Orphans, Children, Adolescents, Vulnerable Children, Adolescents
Orphans and Vulnerable Children Risk Screening Tool Research Study (Zimbabwe)
Investigators propose to assess the sensitivity, specificity, positive and negative predictive value of an HIV Risk Screening Tool in identifying the risk of being HIV-infected among Orphans and Vulnerable Children (OVC) aged…
- Conditions
- Orphans, Children, Adolescents, Vulnerable Children, Adolescents, Community-based
- Trial name
- NCT03343158
- Where
- Zimbabwe
- Volunteers
- 2,260 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Social Isolation in Older Adults, Loneliness
An Innovative App-based Intervention to Promote Social Connectedness and Well-being in Older Adults
This study evaluates the impact of a group-based intervention designed to promote social connectedness and enhance psychological well-being among older adults.
- Trial name
- VITA (NCT07443813)
- Testing
- Blended VITA intervention (hybrid app-based and in-person social engagement program)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Padova
Healthy, Older Adults
Group-Based Exercise Intervention to Prevent Cognitive and Motor Decline
The goal of this clinical trial is to evaluate the efficacy of the Ideomotor Program in healthy older adults living in the community.
- Trial name
- NCT07494149
- Testing
- Ideomotor, Control
- Where
- 2 sites in Italy
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Bergamo
Quality Assurance of Malaria Diagnosis
Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis
The investigators propose to implement a new mobile interface that automatically reads and troubleshoots malaria rapid diagnostic test (RDT) cassettes.
- Trial name
- NCT02504593
- Testing
- mHealth platform employing Fionet Deki Readers to ensure quality of community-based malaria diagnosis
- Where
- Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Duke University
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Postpartum Hemorrhage
Effectiveness, Safety and Feasibility of Auxiliary Nurse Midwives' (ANM) Use of Oxytocin in Uniject™ to Prevent Postpartum Hemorrhage in India
This cluster randomized community-based trial is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by an Auxiliary Nurse Midwife (ANM) at births…
- Trial name
- NCT01108302
- Testing
- Oxytocin in Uniject
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dental Caries in Children
Tooth Smart Healthy Start: Oral Health Advocates in Public Housing
Dental caries is the most common chronic disease of childhood and is increasing in prevalence in children 2-5 years old. Racial and ethnic minority groups as well as economically disadvantaged individuals are affected the most by…
- Trial name
- NCT01205971
- Testing
- Motivational Interviewing, Dental Preventive Services
- Where
- United States
- Volunteers
- 2,842 people, healthy volunteers welcome
- Sponsor
- Boston University
Human Immunodeficiency Virus (HIV)
Intervention to Enhance PrEP Uptake and Adherence in a Community-Based Setting
This study identifies social and behavioral factors likely to influence PrEP acceptability and adherence among men who have sex with men (MSM), and collaborates with a community health center to evaluate a two-stage intervention…
- Trial name
- SPARK (NCT02037594)
- Testing
- Sexual Health Counseling, Enhanced Adherence Intervention, PrEP Information (Active Control)
- Where
- United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Nicotine Dependence
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high…
- Trial name
- STEP3 (NCT06053567)
- Testing
- Aerobic Exercise, Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
COVID-19, Corona Virus Infection
Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)
The purpose of this study is to test the hypothesis that post-exposure prophylaxis with hydroxychloroquine will reduce the symptomatic secondary attack rate among household contacts of known or suspected COVID-19 patients.
- Trial name
- NCT04318444
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
H.Pylori, Gastric Cancer
Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based Study
Background: Helicobacter pylori is a major risk factor for gastric cancer, yet in many developing countries, including Bhutan where gastric cancer incidence is high, access to screening and eradication is limited.
- Conditions
- H.Pylori, Gastric Cancer, H Pylori Eradication
- Trial name
- NCT07211880
- Testing
- Rabeprazole Sodium, Amoxicillin Hydrate, Clarithromycin, Upper gastrointestinal endoscopy for the H. pylori and serum pepsinogen positive individuals (high risk group of gastric cancer), Urea Breath Test for the prevalence of H pylori
- Where
- Bhutan
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- Zero Helicobacter IGAN Network
Human Immunodeficiency Virus, Depression
Community Home-based Care Intervention and Its Health Outcome in HIV-positive People
An intervention study was designed to examine the impact of impact of community home-based care intervention on mental health and treatment outcome in HIV-positive people.
- Conditions
- Human Immunodeficiency Virus, Depression, Stress, Anxiety
- Trial name
- HIV (NCT03505866)
- Testing
- Community home-based care intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Integrated Development Foundation Nepal
Home-dwelling Elderly, Health Care Recipient
Electronic Health Record Sharing System (eHRSS) Encounter Notification Service Pilot Project
This study evaluates the value of the automated notification service that allows more timely information access and sharing. A 12-month RCT will be conducted to determine the efficacy of the provision of the service to an elderly…
- Trial name
- NCT04186351
- Testing
- Encounter notification service
- Where
- Hong Kong
- Volunteers
- 864 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Blood Pressure, Sleep Health
The Sleep2BWell Trial
Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities.
- Conditions
- Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity
- Trial name
- NCT06565104
- Testing
- Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Prevention, STD Prevention
Adopting and Demonstrating the Adaptation of Prevention Techniques: Community PROMISE PLUS
This project will pilot test a step-by-step guide developed by CDC for organizations to engage in evidence-based adaptation of interventions previously shown to be effective in research settings for use in real world…
- Trial name
- NCT00267436
- Testing
- Community PROMISE
- Where
- 2 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Infectious Diseases, Attitude
Omaha System-Based Health Application on Improving Knowledge, Attitude, and Behaviors Regarding Infectious Disease Prevention in the Community
Background: Infectious diseases remain significant public health concerns due to several factors such as climate and environmental changes and natural disasters.
- Conditions
- Infectious Diseases, Attitude, Behavior, Knowledge
- Trial name
- NCT07048301
- Testing
- BUHOS app, Control Group
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Hypertension, Diabetes Mellitus, Type 1
Community Models for Hypertension and Diabetes Care for Refugees
The project will investigate and improve a community health worker (CHW) based model for non-communicable disease (NCD) care in a humanitarian emergency.
- Conditions
- Hypertension, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Comorbidities and Coexisting Conditions
- Trial name
- NCT04229667
- Testing
- Improved Community Health Volunteer (CHV) program
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Rescue Committee