Clinical trials: Community-based
HIV Infections
Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT
The goal of this hybrid (1a) Cluster Randomised Controlled Trial phase 3B trial is to evaluate the effectiveness and implementation of offering a choice of HIV Pre-Exposure Products (PrEP) through community-based sexual and…
- Trial name
- LAPIS (NCT06250504)
- Testing
- APRETUDE (cabotegravir) 600 mg\3 mL, DAPIRING (Dapivirine) 25mg Vaginal Ring, tenofovir disoproxil and emtricitabine
- Where
- South Africa
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Cardiovascular Diseases, Health Behavior
Evaluation of a Socio-ecological Cardiovascular Disease Prevention Intervention for Ultra-Orthodox Jewish Hasidic Women
The purpose of this research study is to design, implement, and evaluate a community level, socio-ecological based CVD prevention intervention using a participatory approach for women in a homogeneous ultra-Orthodox Jewish…
- Trial name
- NCT03201523
- Testing
- Socio-ecologial, community-based intervention
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sarcopenic Obesity
Generative AI-Based Health Education for Older Adults With Sarcopenic Obesity
Sarcopenic obesity is a major public health concern among community-dwelling older adult populations.Encouraging healthy behavior modification through health education emerges as an effective strategy for preventing and treating…
- Trial name
- NCT07782320
- Testing
- Generative AI-based text materials, Generative AI-based video materials, Generative AI-based images materials
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Subjective Cognitive Complaint, Activities Daily Living
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly
Background With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system.
- Conditions
- Subjective Cognitive Complaint, Activities Daily Living, Dementia, Alzheimer Disease
- Trial name
- NCT04265482
- Where
- Chile
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Geroscience Center for Brain Health and Metabolism (Gero)
Risk Behavior, Sexually Transmitted Diseases
A Community-Based Intervention With Popular Opinion Leaders (C-POL) in Texas
After exposure to the C-POL intervention: 1) unprotected vaginal or anal sex, sex with casual partners, concurrent sexual relationships, and exchange of sex for drugs or money will decrease significantly; 2) perceived…
- Trial name
- NCT00260715
- Testing
- Community-Popular Opinion Leader Model, Diffusion of Innovations
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Coronavirus, Coronavirus Infection
COVID-19 Infection and Transmission in Exposed, Confined and Community-based Infants
According to epidemiological models, the seroprevalence of SARS-CoV-2 infection in Île-de-France as of 11 May was between 10 and 15%.
- Conditions
- Coronavirus, Coronavirus Infection, Covid19, Sars-CoV2
- Trial name
- COVIDOCRECHE (NCT04413968)
- Testing
- Rapid detection test, Nasopharyngeal swab, Stool collection
- Where
- 11 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Female Circumcision, Female Genital Mutilation/Cutting
A Community-based Participatory Intervention to Change Attitudes Towards Female Circumcision Among Somali Immigrants in Sweden
Female circumcision (FC) causes both immediate and long-term health consequences. In general, the more severe type of FC, the worse health consequences can be seen.
- Trial name
- NCT02335697
- Testing
- Attitude change towards female circumcision, No intervention
- Where
- Sweden
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Overweight, Obesity
Healthy Creations: Community Based Lifestyle Intervention Validation
There remain important barriers to the translation of the programs like the Diabetes Prevention Program to public health. There is a lack of established lifestyle intervention programs as they are resource and time intensive…
- Trial name
- NCT01262313
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Stunting, Child Development
Improving Early Childhood Development in Zambia
The purpose of this study is to evaluate the impact of a community-based early childhood development (ECD) program on children's physical and cognitive development.
- Trial name
- IECDZ (NCT02234726)
- Testing
- Early Childhood Development Program
- Where
- 2 sites in Zambia
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Zambia Center for Applied Health Research and Development
Aging Well, Dementia
Music Therapy and Social Work Telehealth for Older Adult Well-Being
This study investigates the benefits of using telehealth services, specifically a combination of music therapy and social work support, to improve the well-being of older adults.
- Conditions
- Aging Well, Dementia, Telemedicine
- Trial name
- Melo-SWell (NCT06219148)
- Testing
- Music Therapy Telehealth, Non-Collaborative Social Work Telehealth, Collaborative Social Work Telehealth
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alaine E Hernandez, PhD
Tissue and Organ Procurement, Health Behavior
Community Trial to Enhance Organ Donation
The purpose of this study is to determine the effect of a 5-minute video intervention regarding organ donation and transplantation on increasing the number of organ donor cards signed in Northeastern Ohio Bureau of Motor Vehicles…
- Trial name
- NCT00870506
- Testing
- video
- Where
- United States
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cognitive Behavioral Therapy, Therapy
AI-Based Fidelity Feedback to Enhance CBT
This study is being conducted together by researchers at the University of Pennsylvania and Lyssn.io, Inc., ("Lyssn"), a technology start-up developing digital tools to support evidence-based psychotherapies (EBPs) for mental…
- Trial name
- AFFECT (NCT05340738)
- Testing
- LyssnCBT
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension
Community Vital Signs (CVS): An Integrated Community-Based Approach to Identify Undiagnosed Hypertension in Nigeria
If detected early, hypertension (HTN) is treatable; yet, HTN screening rates are low and inequitable in Sub-Saharan Africa (SSA) leaving many people with undiagnosed HTN, especially in urban areas.
- Trial name
- NCT06659900
- Testing
- CORE Plus (+), CORE
- Where
- Nigeria
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertension
Embedded Community-based Heart-Age Risk Education Trial in Cinese Primary Healthcare
This study evaluates the effectiveness of a brief Heart Age-based risk education intervention embedded in routine primary care for older adults with hypertension in China.
- Trial name
- E-CHARM (NCT07045363)
- Testing
- Cognitive Intervention
- Where
- China
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Duke Kunshan University
Melanoma
Community Based Strategies for Early Detection of Melanoma
The purpose of this study is to pilot the use of community education and digital dermatology to increase the early detection of curable melanomas.
- Trial name
- NCT04799106
- Testing
- Community Based Strategies for Early Detection of Melanoma
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Menopause, Menopause Related Conditions
A Home-based Breathing Training on Menopausal Symptoms
This is a prospective, triple-blinded and randomized controlled trial examining the effects of a home-based breathing training assisted with biofeedback on menopausal symptoms and autonomic functions among community menopausal…
- Trial name
- NCT03082040
- Testing
- home-based breathing training
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ministry of Science and Technology, Taiwan
Healthy People Programs
Boxing Training, Physical-functional Fitness and Cognitive Performance in Older Adults
The aim of the study is to evaluate and to compare the effects of two exercise regimes (Boxing Training -BT and Multicomponent Training -MT) and 12 weeks of follow-up on cognitive health status, physical-functional fitness, and…
- Trial name
- Boxe4Ageing (NCT05826314)
- Testing
- Boxing training, Exercise
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto