Clinical trials: Comorbidities
Dermatoporosis
Prevalence and Comorbidities of Dermatoporosis: a French Prospective Observational Study in General Medicine Consultation
The term dermatoporosis (DP) was proposed by JH. Saurat in 2004 and detailed in 2007 to describe a chronic cutaneous insufficiency and fragility syndrome.
- Trial name
- NCT05699980
- Where
- 15 sites in France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Eczema, Psoriasis
Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring
Inflammatory skin disorders are usually assessed by disease scoring system such as Scoring AD (SCORAD)/Eczema Area and Severity Index (EASI) and Psoriasis Area and Severity Index (PASI) for atopic eczema and psoriasis…
- Trial name
- NCT04809571
- Testing
- Photoacoustic imaging and Confocal Raman spectroscopy measurement
- Where
- Singapore
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Institute of Bioengineering and Bioimaging (IBB)
Alcohol Abuse, Drug Abuse
Personality-targeted Interventions for Adolescent Alcohol Misuse
Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press).
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Preventure (NCT00344474)
- Testing
- PRE-Venture: Personality Risk Education
- Where
- United Kingdom
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity, Cardiovascular Disease
Effect of Alpha Lipoic Acid on Obesity Related Comorbidities
The major objective of this study is to conduct a double-blind, placebo-controlled, randomized clinical trial to assess whether oral alpha lipoic acid supplementation will decrease cardiovascular disease and type 2 diabetes risk…
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes
- Trial name
- NCT00994513
- Testing
- Alpha Lipoic Acid
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Augusta University
Various Comorbidities
Pulse CO-Oximetry Noninvasive Monitoring and Laboratory Measurements of Subject Blood Samples
Characterize Masimo noninvasive technology in spot check reading on subjects and make comparison to invasive blood sampling tested on reference analyzers.
- Trial name
- NCT01638455
- Testing
- Noninvasive device
- Where
- United States
- Volunteers
- 2,776 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Comorbidity, Domestic Violence
Questionnaire to Study Violence Against Women in the Climateric's Phase.
Objectives - To construct and validate a questionnaire evaluating violence suffered by women during any phase of their lives and health repercussions during climactery.
- Conditions
- Comorbidity, Domestic Violence, Sexual Abuse
- Trial name
- NCT01158768
- Where
- Brazil
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Attention-deficit/Hyperactivity Disorder
Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity.
- Trial name
- WMT for ADHD (NCT06376331)
- Testing
- washed microbiota transplantation
- Where
- 2 sites in China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Mental Health Disorder, Substance Use Disorder
The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta
This project consists of a pilot trial to assess the preliminary impact of a stigma-reduction training to reduce clinic-level stigma and the You℞ Decision prescribing platform to increase HIV care providers' self-efficacy related…
- Conditions
- Mental Health Disorder, Substance Use Disorder, Stigmatization, Implementation Science
- Trial name
- IMPROV (NCT05415891)
- Testing
- Modified Health Policy Project (HPP) HIV-Stigma and Discrimination Reduction Training Curriculum, You℞ Decision prescribing platform
- Where
- 2 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- RTI International
To Reduce the LDL-C Level in Hypercholesteremia Adult Patients, Combination for Subgroup High LDL-c Patients With Other Comorbidities
Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects
Objectives: The primary and secondary objectives of the study are presented below. Exploratory objectives are presented in the body of the protocol.
- Trial name
- NCT05905068
- Testing
- RN0191 INJECTION
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ikaria Bioscience Pty Ltd
Asthma, Late-Onset Asthma
General Risk Factors and Inflammatory Determinants in Older Patients With Asthma
A cross-sectional study in asthma patients to determine if a late age of onset asthma (start symptoms >18 years old), is associated with more persistent airway/systemic inflammation, worse asthma control, more co-morbidity, a…
- Conditions
- Asthma, Late-Onset Asthma, Childhood Asthma
- Trial name
- GRANDMA (NCT03278561)
- Testing
- Sputum induction, Blood sample
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gerdien Tramper
Heart Failure
MAgna GraecIa Evaluation of Comorbidities in Patients With Heart Failure STUDY
The MAGIC-HF STUDY project (MAgna GraecIa evaluation of Comorbidities in patients with Heart Failure STUDY), is an observational prevalence and incidence study focusing on the role that risk factors, various comorbidities, and…
- Trial name
- MAGIC-HF (NCT05915364)
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Psoriasis, Psoriasis Vulgaris
Biofeedback for Psoriasis
We are conducting a proof-of-concept trial to study the impact of HRV-biofeedback, a mind-body technique designed to improve stress resilience, on the quality of life, mood, and clinical skin severity of patients with psoriasis.
- Conditions
- Psoriasis, Psoriasis Vulgaris, Psychophysiological Disorder, Anxiety
- Trial name
- NCT05506644
- Testing
- HRV-Biofeedback/Mind-Body Therapy
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Low Back Pain, Depression
Subgroups of Older Adults With Back Pain and Multiple Chronic Conditions
The overall goal of this study is to use the National Health and Aging Trends Study (NHATS) data to gain an understanding of how multiple chronic conditions impact the health outcomes of older adults with back pain.
- Conditions
- Low Back Pain, Depression, Anxiety, Osteoarthritis
- Trial name
- NCT03632122
- Where
- United States
- Volunteers
- 8,344 people, healthy volunteers welcome
- Sponsor
- University of Washington
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Posttraumatic Stress Disorder, Major Depressive Disorder
Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
This study is a randomized controlled trial comparing an integrated treatment, Behavioral Activation + Cognitive Processing Therapy (BA + CPT), to CPT alone among active-duty service members with posttraumatic stress disorder…
- Trial name
- NCT02874131
- Testing
- Behavioral Activation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego