Clinical trials: Comorbidities and Coexisting Conditions
Diabetes Mellitus, Comorbidities and Coexisting Conditions
MDT Conferences for People With Diabetes and Multimorbidity
The goal of this observational study is to test if regular meetings (multidisciplinary team conferences) between several different medical doctors can work well in everyday hospital life.
- Trial name
- NOMAD (NCT05913726)
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Odense University Hospital
Frailty, Comorbidities and Coexisting Conditions
Frailty in Outpatient Digestive Endoscopy
The increase in our society of the proportion of frail people who suffer from disability and dependency forces us to detect modifiable factors and therefore subject to intervention that can adapt health care for frail patients in…
- Conditions
- Frailty, Comorbidities and Coexisting Conditions, Complication
- Trial name
- FRIEND (NCT06507527)
- Testing
- Collection of variables
- Where
- Spain
- Volunteers
- 1,474 people
- Sponsor
- Parc de Salut Mar
Stroke, Acute, Comorbidities and Coexisting Conditions
Giessen Stroke Registry
The aim of the planned study project is to assess the current situation regarding the treatment of patients with stroke. Specifically, various treatment strategies are to be associated and correlated with clinical endpoints…
- Conditions
- Stroke, Acute, Comorbidities and Coexisting Conditions, Critical Care
- Trial name
- GIST (NCT05295862)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Giessen
Smoking Cessation, HIV
Evaluating Smoking Cessation Interventions for PWH in South Africa
The overall objective of the study is to optimize a smoking cessation treatment package for people with HIV (PWH) that can be integrated into existing HIV care in South Africa.
- Conditions
- Smoking Cessation, HIV, Comorbidities and Coexisting Conditions
- Trial name
- Tlogela (NCT05413122)
- Testing
- Varenicline, Nicotine patch, Nicotine gum
- Where
- South Africa
- Volunteers
- 660 people
- Sponsor
- Johns Hopkins University
Heart Failure With Preserved Ejection Fraction, Sarcopenia
Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure.
The main objective of the study is to assess the effectiveness of a cardiac rehabilitation program on functionality, measured by kinematic analysis, cardiorespiratory capacity, and ventricular ejection fraction in elderly…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Sarcopenia, Frail Elderly Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- FUNNEL+ (NCT05393362)
- Testing
- Cardiac Rehabilitation Program (CR), Control Group (CG)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Malaga
COVID, Severe Acute Respiratory Syndrome
Obesity and Mortality of Critically Ill Patients With COVID-19
Disproportionate impact of COVID-19 in patients with obesity is now well established. Obesity is associated with severe forms of COVID-19 and may be a risk factor of intensive care unit (ICU) admission.
- Conditions
- COVID, Severe Acute Respiratory Syndrome, Obesity, Comorbidities and Coexisting Conditions
- Trial name
- COV-OB-ICU (NCT04425213)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Rectal Cancer, Comorbidities and Coexisting Conditions
Watch and Wait Management on Rectal Cancer Patients Using New Swift Local Therapy
Within our institution, the principal investigator have acquired expertise in endorectal brachytherapy, a localized treatment for colorectal cancer.
- Conditions
- Rectal Cancer, Comorbidities and Coexisting Conditions, Inoperable Disease, Brachytherapy
- Trial name
- Whistle (NCT04336202)
- Testing
- External beam radiotherapy + Endorectal brachytherapy
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD)
Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)
To assess the safety, feasibility and preliminary efficacy of ketamine-enhanced therapy (KET) for alcohol use disorder (AUD) and comorbid major depressive disorder (MDD) in an open-label, single arm, pilot clinical trial.
- Conditions
- Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD), Comorbidities and Coexisting Conditions
- Trial name
- KET-DUAL (NCT07247370)
- Testing
- Ketamine, Cognitive Behavioural Therapy
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- South West Sydney Local Health District
Quality of Life, Obstetric Complication
Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Quality of Recovery Score
The goal of this prospective observational study is to learn about the correlation between obstetric comorbidity index and obstetric quality of recovery score in pregnant patients who undergo cesarean section.
- Conditions
- Quality of Life, Obstetric Complication, Cesarean Section Complications, Comorbidities and Coexisting Conditions
- Trial name
- NCT05704179
- Testing
- Obstetric Quality of recovery score
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Weight Loss, Bariatric Surgery Candidate
Conversion to SADI-S, RYGB or OAGB After Failed Sleeve
Assess what revisional surgery is superior and provides the best weight loss after primary LSG. What is the occurrence of complications and the nutritional laboratory status? And if the resolution and /or improvement of…
- Conditions
- Weight Loss, Bariatric Surgery Candidate, Comorbidities and Coexisting Conditions, Nutrient Deficiency
- Trial name
- RCTresleeve (NCT05608772)
- Testing
- revision surgery
- Where
- Egypt
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Colon Cancer, Malnutrition
The Patient in Laparoscopic Colon Surgery:Impact of Comorbidities,Frailty,Malnutrition and Sarcopenia on Short-term Mortality
There are many factors involved in outlining the patient's profile and in defining which factors can be configured as risks related to the surgical act; for the modern surgeon it is no longer possible to identify the patient at…
- Conditions
- Colon Cancer, Malnutrition, Sarcopenia, Comorbidities and Coexisting Conditions
- Trial name
- NCT04729738
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- University Hospital of Ferrara
Cognitive Impairment, Dementia
Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial
Dementias secondary to cerebrovascular diseases are of significant epidemiological and clinical relevance. As a result, the management of individuals with comorbid dementia should involve early diagnosis, effective treatment, and…
- Conditions
- Cognitive Impairment, Dementia, Comorbidities and Coexisting Conditions, Vascular Dementia
- Trial name
- RCTCogRehab (NCT05954741)
- Testing
- Motor rehabilitation alone, Motor rehabilitation and Cognitive rehabilitation (paper-based), Motor rehabilitation and cognitive rehabilitation (digital-based)
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Rare Diseases, Epidemiology
Verification of the Epidemiology and Mortality of Rare Diseases in Taiwan With Real-world Evidence
This study aims to explore the longitudinal incidence and prevalence trends of selected muscular and bone-related rare diseases, i.e., Familial Amyloidotic Polyneuropathy (FAP), Primary hyperoxaluria, Wilson's disease, Cystic…
- Conditions
- Rare Diseases, Epidemiology, Morbidity, Morality
- Trial name
- NCT05367115
- Testing
- longitudinal observational study
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- National Cheng-Kung University Hospital
Polytrauma, Red Blood Cell Distribution Width
Red Blood Cell Distribution Width and Charlson Comorbidity Indeces in the Frail Polytraumatized Patient.
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 2012 to December 2015.
- Conditions
- Polytrauma, Red Blood Cell Distribution Width, Comorbidities and Coexisting Conditions
- Trial name
- NCT05221476
- Testing
- retrospective
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
COVID-19, Comorbidities and Coexisting Conditions
Telerehabilitation in Patients With COVID-19 After Hospitalization. The ATHLOS Study
This is a two-phase multicenter study that will be conducted in collaboration with five university hospitals, in order to offer telehealth services at home in patients with COVID-19, after hospital discharge.
- Trial name
- ATHLOS (NCT04368845)
- Testing
- Telerehabilitation
- Where
- Greece
- Volunteers
- 82 people
- Sponsor
- University of Thessaly
Comorbidities and Coexisting Conditions, Morality
Registry for Hypoparathyroidism Wuerzburg
Long-term conventional treatment of chronic hypoparathyroidism does not fully restore calcium homeostasis leading to increased morbidity, emergency events and reduced subjective health status.
- Conditions
- Comorbidities and Coexisting Conditions, Morality, Hypocalcemia, Hypercalcemia
- Trial name
- NCT05585593
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University of Wuerzburg
Comorbidities and Coexisting Conditions
Prevalence of Comorbidities in Patients Undergoing Oncosurgeries at Tertiary Cancer Institute in North India.
Investigators plan to study the prevalence of comorbidities in patients undergoing oncosurgeries
- Trial name
- oncosurgery (NCT05038501)
- Testing
- To study comorbidities in patients undergoing Oncosurgeries
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Liver Transplantation, Comorbidities and Coexisting Conditions
The Danish Comorbidity in Liver Transplant Recipients Study
Background: Liver transplantation is the only curative treatment for patients with end-stage liver disease. Short-term survival has improved due to improved surgical techniques and greater efficacy of immunosuppressive drugs.
- Trial name
- DACOLT (NCT04777032)
- Where
- 4 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Helicobacter Pylori Infection, Comorbidities and Coexisting Conditions
Real-world Treatment of H. Pylori Eradication in Patients with Comorbidity
Most of the studies of H. pylori eradication were conducted in academic institutes and designed to enrolled patients who did not have comorbidities.
- Conditions
- Helicobacter Pylori Infection, Comorbidities and Coexisting Conditions, Real-world Outcome, Medication Adherence
- Trial name
- Real-world_Hp (NCT05475431)
- Testing
- The sequential therapy, The triple therapy, The hybrid therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 1,053 people
- Sponsor
- National Cheng-Kung University Hospital
HIV Infections, Drug Interaction
Variation in Drug Interactions in People With HIV (PLWH) Aged 60 Years and Older.
Several cohort studies have recently shown a significant increase in the mean age of PLWH ( People Living With HIV) and in the prevalence of people in advanced age in the various cohorts, as a result of the marked increase in the…
- Conditions
- HIV Infections, Drug Interaction, Elderly Infection, Comorbidities and Coexisting Conditions
- Trial name
- NCT06717581
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna