Clinical trials: Comparative Study
Chronic Pelvic Pain Syndrome
Efficacy of Cognitive Behavior Therapy for Treatment of Chronic Pelvic Pain in Women
The study will employ 4 treatment arms and 1 placebo arm to compare efficacy of CBT, PFT, Pharmacotherapy, Integrated CBT and PFT modalities in the management of chronic pelvic pain in women.
- Trial name
- NCT07042555
- Testing
- CBT-cp, Pelvic Floor Therapy, Pharmacotherapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Fracture of Lower Limb
Comparing Heavy Levobupivacaine With Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine.
The purpose of this study is to compare the non-inferiority between Heavy Levobupivacaine with Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine During Spinal Anesthesia for Orthopedic Procedures in the Lower Limbs.
- Trial name
- NCT01308047
- Testing
- Bupivacaine
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Relapsing-remitting Multiple Sclerosis
Comparative Oral Bioavailability Study of MT-1303
The purpose of this study is to assess the comparative oral bioavailability of a Formulation B versus the Formulation A of MT-1303.
- Trial name
- NCT02310048
- Testing
- MT-1303-FormA, MT-1303-FormB
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma Corporation
Common Bile Duct Closure
Comparative Study of Three Common Bile Duct Closure Techniques
This study evaluates the efficacy and safety of three different methods of CBD repair after common bile duct exploration and provides more evidence for selecting the optimal duct closure after choledocholithotomy.
- Trial name
- NCT04264299
- Testing
- T tube drainage, Primary closure, Antegrade stenting
- Where
- Egypt
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- South Valley University
Ulcers, Duodenal and Gastric
Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of ASA (Acetylsalicylic Acid) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fasting Conditions
An open label, balanced, randomized, three-treatment, three-period, six-sequence, cross-over, single dose, comparative bioavailability pilot study under fasting conditions.
- Trial name
- NCT01847404
- Testing
- Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one, Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two, ASA 100 mg tablet
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Normal Volunteers
Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Citalopram on Motivation
The aim of the current study is to examine the role of serotonin on the cognitive parameters of motivation. They are embedded in a conceptual framework of motivation that merges decision-making and reinforcement learning…
- Trial name
- MBBCitalopram (NCT02113943)
- Testing
- Citalopram 30mg
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Flat Feet
Comparative Study Between Russian And Exercise in Subjects With Flexible Flatfoot
The prevalence of flexible flat foot was 13.6% in adults a cross-sectional Study (for males-12.8%; for females-14.4%).18-21-year-old Indian adults.
- Trial name
- NCT06530238
- Testing
- Russian Currents
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deraya University
Colorectal Canceer
Usefulness of Endocuff in the Adenoma Detection Rate. Comparative Study
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. The cumulative risk of developing CRC is about 6% lifelong.
- Trial name
- NCT02387593
- Testing
- ENDOCUFF
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Halitosis
Comparative Study Between Photodynamic Therapy With Urucum and LED and Probiotics in Halitosis Reduction
Introduction: Halitosis is a term that defines any foul odor emanating from the oral cavity. The origin may be local or systemic.
- Trial name
- NCT03996044
- Testing
- Teeth brushing and flossing, Tongue scraping, Antimicrobial Photodynamic Therapy (aPDT)
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Weight Loss
A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition
The purpose of this study is to determine whether subjects taking a supplement designed to increase metabolic rate will have a positive effect on body composition (fat mass, muscle mass, and bone density.)
- Trial name
- NCT01423019
- Testing
- Advantra Z, Advantra Z + Naringin + Hesperiden, Sugar pill
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Healthy
Pharmacokinetics and Pharmacodynamics Study of BCD-066 Compared to Aranesp® in Healthy Volunteers
This is a randomized double-blind crossover study of pharmacokinetics, pharmacodynamics and safety of BCD-066 (darbepoetin alfa manufactured by CJSC BIOCAD, Russia) and Aranesp® (Amgen Europe B.V., Netherlands) in healthy…
- Trial name
- NCT02506881
- Testing
- Darbepoetin alfa
- Where
- Russia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Biocad
Infertility
Comparative Bioavailability Study of Human Chorionic Gonadotropin (hCG)-IBSA Versus a Marketed hCG Formulation
In the present study, the rate and extent of hCG absorption will be compared between the two treatments in healthy women aged 20 to 45 years.
- Trial name
- NCT03735030
- Testing
- Human hCG 10'000 IU, Recombinant hCG 6'500 IU
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IBSA Institut Biochimique SA
Periapical Abscess
Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
Investigators observed the clinical and radiographic healing of periapical lesion using Chitosan mixed with calcium hydroxide and compared it with triple antibiotic paste when used as intracanal medicament in 3months, 6 months…
- Trial name
- NCT04319575
- Testing
- root canal treatment and intracanal medicament
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Iron Deficiency
Mineral Absorption From Fortified Rice Produced With Different Fortification Techniques
The investigators studies will compare iron, respectively iron and zinc bioavailability from fortified rice produced from different fortification techniques using stable isotopic labels.
- Trial name
- NCT02572128
- Testing
- Fortified rice
- Where
- 2 sites in Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Comparative Bioavailability Study Between Ticagrelor and ASA Administered Individually or in Combination.
Study conducted to determine and compare the relative bioavailability of two solid oral formulations (reference versus test) of the non-fixed combination of Ticagrelor 90 mg (Brilinta by AstraZeneca S.A.
- Trial name
- NCT07444164
- Testing
- A1: Ticagrelor / Acetylsalicylic acid in fixed dose combination capsule. (Laboratorios Silanes S.A. de C.V.), A2: Ticagrelor (BRILINTA®, AstraZeneca S.A. de C.V.) A3: Acetylsalicylic Acid (ASPIRINA JUNIOR®, Bayer de México S.A. de C.V.)
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Supraclavicular Brachial Plexus Block
Parasagittal Vs Cornerpocket Approaches
Brachial plexus blocks are widely used to provide anesthesia for upper limb surgery. Although many different approaches to the brachial plexus block have been described, there is widespread acceptance that injecting at the…
- Trial name
- NCT06352333
- Testing
- supraclavicular ultrasound guided brachial plexus block
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Myopia
Myopia Control With Novel Eye Drops
Myopia currently affects 30% of the world and by 2050, almost 50% of the world will be myopic based on conservative estimates.1 In 2050, this will equate to almost 5 billion people with myopia, and those with high myopia will…
- Trial name
- NCT04301323
- Testing
- BHVI1 eye drops, BHVI2 eye drops, BHVI3 eye drops
- Where
- Vietnam
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
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