Clinical trials: Comparative Study
Psoriasis
Comparative Study to Evaluate the Pharmacokinetics of BAT2206 vs Stelara® in Healthy Subjects
It is a randomized, double-blinded, single-dose, 3-arm parallel, comparative study to evaluate the pharmacokinetics, safety and immunogenicity of BAT2206 Injection vs Stelara® (EU-licensed and US-licensed) in healthy Chinese male…
- Trial name
- NCT04371185
- Testing
- BAT2206, Stelara(US-licensed), Stelara(EU-licensed)
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Inguinal Hernia
SetUp Study for HugoTM RAS Inguinal Hernia Repair
The goal of this observational cohort study is to evaluate the evolution of the operative time in performing robotic-assisted laparoscopic inguinal hernia repair (rTAPP) during the learning curve of the first 50 patients using…
- Trial name
- SUSHI (NCT06599515)
- Testing
- robotic surgical platform
- Where
- 2 sites in Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Coronavirus Infections
Comparative Study of Hydroxychloroquine and Ivermectin in COVID-19 Prophylaxis
We have to be aware of the challenge and concerns brought by 2019-nCoV to our healthcare workers. Front-line healthcare workers can become infected in the management of patients with COVID-19; the high viral load in the…
- Trial name
- NCT04384458
- Testing
- Hydroxychloroquine, Ivermectin
- Where
- Brazil
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Satisfaction, Product Quality
Surgeons' Satisfaction With Two Types of Tinted Chlorhexidine Applicators (Chloraprep® and Nex Clorex 2%)
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the adequate sterilization of the surgical…
- Trial name
- NCT03508492
- Testing
- Surgical tinted Chloraprep® applicators, Surgical tinted Nex Clorex 2% applicators
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cristina Fernandez Perez
Dental Anxiety, Impacted Third Molar Tooth
Three Anxiolytic Drugs Used in Third Molar Surgery
This study was to compare the effectiveness of three drugs (Passiflora incarnata, Erythrina mulungum, Midazolam) in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT02065843
- Testing
- Mulungu, Passiflora incarnata, midazolam
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Influenza
Influenza Vaccine in Pediatric Transplant Subjects
The purpose of this study is to evaluate how well children responds to the recommended trivalent subviron influenza vaccine (flu shot).
- Trial name
- NCT00133510
- Testing
- Trivalent Subviron Influenza vaccine (Fluzone)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hip Arthropathy, Hip Disease
Cardiac Index and General Anesthesia Without Opioid.
General anesthesia used to be based on the association of hypnotics and opioid drugs. But recent studies showed that opioids may be related to a many different complications, like respiratory distress, hyperalgesia.
- Trial name
- OFFLOW (NCT05446623)
- Testing
- Dexmedetomidine, Sufentanil
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Montauban
Pediatric-onset Multiple Sclerosis
Respiratory Functions in Pediatric-Onset Multiple Sclerosis
Pediatric-onset multiple sclerosis (POMS) is a chronic, autoimmune and inflammatory disease of the central nervous system that begins before the age of 18 years.
- Trial name
- NCT05123924
- Testing
- Evaluation of respiratory capacity, respiratory muscle strength and fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Acute Respiratory Distress Syndrome
Ultrasonic Weaning Criteria in Prolonged Ventilation
compare and evaluate the effect of use of ultrasonic criteria of weaning versus the conventional ways of weaning in post-traumatic acute respiratory distress syndrome (ARDS) patients who were ventilated for a long time.
- Trial name
- NCT05794867
- Testing
- clinical weaning criteria
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King Abdul Aziz Specialist Hospital
Type 2 Diabetes
A Pharmacokinetic Study Comparing the Liraglutide Injection (RD12014) and Victoza® in Healthy Chinese Subjects
To evaluate the pharmacokinetics similarity between the liraglutide injection (RD12014) produced by Sunshine Lake Pharma Co., Ltd.
- Trial name
- NCT05294536
- Testing
- Liraglutide injection,RD12014, Liraglutide injection,Victoza
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Peri-implant Soft Tissue Healing, Soft Tissue Management in Subcrestal Dental Implants
Comparative Clinical Study of Conventional vs Customized Healing Abutments in Dental Implantology
This clinical study evaluates how different healing abutment designs influence the healing and preservation of the soft tissues surrounding dental implants.
- Conditions
- Peri-implant Soft Tissue Healing, Soft Tissue Management in Subcrestal Dental Implants, Healing Abutment Influence on Gingival Volume
- Trial name
- NCT07031232
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol Using Healing Abutments
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy Volunteers
Evaluation of Synergistic Anti-plaque Activity of Salvadora Persica L. and Green Tea: A Clinical Comparative Study
Accumulation of dental plaque may result in negative effects on the tooth and tooth supporting periodontal tissue. In addition, it contributes to the development of caries and periodontal diseases.
- Trial name
- ESAA (NCT02624336)
- Testing
- DTC1, Oradex, Distilled water
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Healthy Adult Males Volunteers
A Comparative Bioavalability Study of Tamsulosin 0.4 mg Prolonged-release Tablets Versus the Reference Drug Omnic Ocas®, Tabsulosine 0.4 mg Tablets in Healthy Adult Male Subjects, at Steady State
The aim of this study is to evaluate the bioequivalence and safety of Tamsulosin hydrochloride 0.4 mg, prolonged-release tablets (Synthon Hispania SL, Spain), compared to Omnic Ocas®, Tamsulosin hydrochloride 0,4 mg…
- Trial name
- NCT07146711
- Testing
- Tamsulosin (0.4 mg/j), Omnic Ocas®,
- Where
- Armenia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Berlin-Chemie AG Menarini Group
Allergies
To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fed Conditions
To demonstrate the relative bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg ER tablets under fed conditions.
- Trial name
- NCT00881634
- Testing
- Cetirizine HCl/Pseudoephedrine HCl 5 mg/120 mg Tablets (Sandoz, USA), Zyrtec-D 12 Hour 5 mg/120 mg Extended Release Tablets (Pfizer, USA)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sandoz
Cutibacterium Acnes Contamination
Wound Irrigation Comparative Effectiveness Study
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline…
- Trial name
- NCT06379919
- Testing
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Gingival Papillary Blunting
Effect of Different Suturing Technique on Height of Interdental Papilla and Periodontal Healing
Comparative clinical evaluation of internal mattress sutures vs continuous independent sling sutures on interdental papilla height and periodontal healing in esthetic zone.
- Trial name
- NCT03429764
- Testing
- CISS, VIMS
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Diseases
Digital PCR for Quantifying Periodontal Pathobionts
Comparison of quantitative polymerase chain reaction (qPCR) and digital polimerase chain reaction (dPCR) quantification of subgingival plaque samples.
- Trial name
- dPCR (NCT06692595)
- Testing
- digital PCR
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Bioequivalence
The Bioequivalence Study of Two Different Formulations of Candesartan Cilexetil After a Single Oral Dose Administration Under Fasting Conditions
This single dose study was designed in accordance with EMA (the European Medicines Agency) regulatory guidelines, with the aim of characterizing the bioavailability of candesartan in the two formulations in healthy subjects.
- Trial name
- NCT04012307
- Testing
- Candesartan Cilexetil 32mg, Atacand® PROTECT
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Post Spinal Hypotension
Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section
Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section
- Trial name
- NCT05587153
- Testing
- perfusion index in all parturient recruited for the study
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Eyebrow Hypotrichosis, Thin Eyebrow
Minoxidil 1% for Eyebrow Enhancement
The purpose of the study is to compare efficacy and safety of minoxidil 1% versus placebo in enhancement of eyebrows.
- Trial name
- NCT01924000
- Testing
- Minoxidil lotion 1%
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University Hospital
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