Clinical trials: Comparative Study
Acanthosis Nigricans
Efficacy and Safety Of Fractional Carbon Dioxide Laser Plus Topical Metformin In Treatment Of Acanthosis Nigricans
evaluate and compare the clinical Efficacy \& Safety Of Fractional Carbon Dioxide (Co₂) Laser Plus Topical Metformin In Treatment Of Acanthosis Nigricans.
- Trial name
- NCT07760181
- Testing
- Topical metformin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Healthy Volunteers, Fasting
Comparative Bioavailability Study of TAH3311 5 mg Oral Dissolving Film vs ELIQUIS® 5 mg Tablet in Healthy Volunteers
The goal of this clinical trial is to evaluate the pharmacokinetic profiles and bioequivalence, and to determine the safety and tolerability of the TAH3311 Oral Dissolving Film (ODF) 5mg compared with ELIQUIS® (Apixaban) 5mg Oral…
- Conditions
- Healthy Volunteers, Fasting, Fed
- Trial name
- NCT05995119
- Testing
- Apixaban 5 mg Oral Dissolving Film (TAH3311) and Tablet (Eliquis®)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TAHO Pharmaceuticals Ltd.
Coenzyme Q Deficiency
Comparative Single-dose Bioavailability Clinical Study of Different Coenzyme Q10 Products
The randomized, open-label, three period crossover single-dose bioavailability study with three coenzyme Q10 products
- Trial name
- NCT05272228
- Testing
- Dietary supplement - standard product, Dietary supplement - Investigational product IP1, Dietary supplement - Investigational product IP2
- Where
- Slovenia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Healthy
Efficacy of Dietary Supplement in Subjects With Acid Reflux and/or Abdominal Bloating/Distention and GI Symptoms
This study was a prospective randomized clinical study. There was interventional treatment for a total of 8 weeks including a 2-week washout period.
- Trial name
- NCT06808867
- Testing
- Dietary Supplement with Active Ingredient Blend
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Addition of Hyalase to Local Anesthetic in Scalp Block
Safety and Efficacy of Addition of Hyaluronidase to Lidocaine and Bupivacaine in Scalp Nerves Block in Elective Craniotomy Operations, Comparative Study
Safety and efficacy of addition of hyaluronidase to lidocaine and bupivacaine in scalp nerves block in elective craniotomy operations,Comparative study
- Trial name
- NCT03411330
- Testing
- Hyaluronidase, Lidocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block
Erector Spinae Plane Block Versus Modified Thoracoabdominal Nerve Block for Analgesia in Pediatric Laparoscopic Abdominal Surgeries
Laparoscopic abdominal surgeries are frequently performed in pediatric patients and are often associated with significant postoperative pain, which, if inadequately managed, may delay recovery and increase the risk of chronic…
- Conditions
- Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block, Modified Thoracoabdominal Nerve Block (M-TAPA)
- Trial name
- NCT07240064
- Testing
- Erector Spinae Plane Block, Modified thoracoabdominal plane block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Scalp Laceration
Comparison Study on Hair Apposition Technique Performed Between Nurses and Doctors in Emergency Department.
The purpose of this study is to compare the effectiveness, complications and benefits of Hair Apposition Technique(HAT)performed by nurses or doctors.
- Trial name
- NCT00353769
- Testing
- Hair Apposition Technique
- Where
- Singapore
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Healthy
Ibuprofen and Pseudoephedrine Comparative Pharmacokinetic Study
This comparative pharmacokinetic study is being conducted to provide supporting evidence for inclusion in dossiers to regulatory authorities for an Article 8(3) of Directive 2001/83/EC abridged application for ibuprofen and…
- Trial name
- NCT03184766
- Testing
- Test Nurofen Cold and Flu®, Ibuprofen and pseudoephedrine liquid capsules, Comparator 1 Nurofen Cold and Flu®, ibuprofen and pseudoephedrine tablets, Comparator 2 Nurofen Immedia 200 mg Weichkapseln, ibuprofen liquid capsules
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Diabetes Mellitus, Type 2
The Value of Using Colostrum Supplements on the Physical Performance and Cognitive Function in Healthy Subjects and Type 2 Diabetes
The goal of this interventional Randomized clinical is to compare the effect of colostrum pharmaceutical preparation and placebo in a sample of Iraqi participants. The main questions to answer are: 1.
- Trial name
- NCT06549556
- Testing
- Colostrum Capsule 500 mg (Colostrum® 500 mg Veg Capsules, nowfoods®, Illinois, USA)
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Rasheed University College
Breast Cancer
Initial Evaluation of Ultra FAST Breast Magnetic Resonance in Breast Cancer Screening: Comparative Study With Mammography and Ultrasound.
Mammography remains an imperfect screening test especially in women with extremely dense breast tissue, missing biologically aggressive cancers especially in younger population and picking up indolent cancers that do not need…
- Trial name
- NCT02324894
- Testing
- MRI screening
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Breast Neoplasm Female
Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer
Proof of Concept retrospective study. Women who have the diagnosis Breast Cancer ( confirmed by biopsy) will donate a blood samples.
- Trial name
- NCT04927130
- Testing
- ARNA Breast
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ARNA Genomics US Inc.
Bacterial Microflora Reduction
Comparative Study of Antimicrobial Effectiveness
Comparative Study of Antimicrobial Effectiveness Evaluation of 26 ml Project X, 5.1ml Project X and Prevantics® Maxi Swabstick following ASTM E1173 - Standard Test Method for Evaluation of Preoperative, Precatheterization, or…
- Trial name
- NCT03817580
- Testing
- Project X 26ml, Project X 5.1ml, Prevantics Maxi Swabstick
- Where
- Romania
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Alcoholism, Depression
Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism.
The aim of the present study was to examine the influence of memantine, a noncompetitive NMDA receptor blocker, in depression co-morbid with long term alcohol heavy use comparing to SSRI-inhibitor, escitalopram.
- Trial name
- NCT00368862
- Testing
- Ebixa (memantine hydrochloride), Cipralex (escitalopram)
- Where
- Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Opioid Free Anesthesia
A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery
Patients undergoing nephrectomy have a high incidence of postoperative pain. In the perioperative period, these patients are often treated with patient-controlled opioids, epidural analgesia, or both.
- Trial name
- NCT05312541
- Testing
- pre emptive local anaesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Bioequivalence Study in Healthy Subjects
Comparative Study of the Pharmacokinetics and Bioequivalence of Two Flupentixol Formulations
To establish bioequivalence between new film-coated tablet formulations of 0.5 mg, 1 mg and 5 mg flupentixol and the marketed coated tablet formulations of 0.5 mg, 1 mg, and 5 mg flupentixol, administered as single doses
- Trial name
- NCT02660840
- Testing
- 0.5 mg Flupentixol film-coated tablet (test treatment), 1 mg Flupentixol film-coated tablet (test treatment), 5 mg Flupentixol film-coated tablet (test treatment)
- Where
- Russia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Phenylketonuria
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
Effect of L-carnitine supplementation on phenylalanine and brain-derived neurotrophic factor levels in infants and children with phenylketonuria L-carnitine is mainly obtained from foods such as red meat and milk that are limited…
- Trial name
- NCT06901323
- Testing
- L-carnitine
- Where
- Egypt
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anxiety
Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery
Objective: The aim of the present study was to compare hemodynamic changes using 7.5 mg of midazolam and 10.0 mg of diazepam during the surgical removal of symmetrically positioned third molars.
- Trial name
- NCT02177955
- Testing
- 7.5 mg Midazolam, 10 mg diazepam
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jimmy Barbalho
Healthy
A Bio-equivalence Study of Sofosbuvir From Sofodelevier 400 mg Film Coated Tablets (Al-debeiky Pharma, Egypt) Versus Sovaldi 400 mg Tablets (Gilead Sciences, Canada)
Comparative randomized, single dose, three way three sequence two treatment partial replicate crossover open-label study to determine the bioequivalence of Sofosbuvir from Sofodelevier 400 mg F.C.T (Al-debeiky pharma, Egypt)…
- Trial name
- NCT03062423
- Testing
- Sofodelevier, Sovaldi (fist dose), Sovaldi (second dose)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt
Cesarean Section Complications
The Effect of Placental Spontaneous Delivery Versus Manual Removal on Blood Loss During Cesarean Section. A Comparative Study
The mode of placental delivery may contribute to an increase or decrease in the morbidity associated with CS, and many studies have shown it to be a key role in determining the blood loss during CS.
- Trial name
- NCT05395585
- Testing
- Manual placental separation
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain Management, After VATS
Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is a commonly performed minimally invasive procedure that has lead to lower levels of pain.
- Trial name
- NCT06836635
- Testing
- ESPB group, TPVB group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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