Clinical trials: Complex Gastrointestinal Surgery
Lung Cancer, Esophageal Cancer
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas
Background: Certain types of lung, esophageal, or thymic cancers and mesotheliomas have specific antigens (protein molecules) on their surfaces.
- Conditions
- Lung Cancer, Esophageal Cancer, Malignant Pleural Mesothelioma, Sarcoma
- Trial name
- NCT01143545
- Testing
- Allogeneic Tumor Cell Vaccine (K562), Celecoxib, cyclophosphamide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Hepatic Carcinoma
Impact of Three-dimensional Visualization on Operation Strategy and Complications for Complex Hepatic Carcinoma
The aim of the multi-centre study is to evaluate correctly the impact of three dimensional visualization on operation strategy and complications for complex hepatic carcinoma.
- Trial name
- NCT03132740
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Zhujiang Hospital
Liver Cancer
Intensive Neoadjuvant Chemotherapy in Treating Young Patients Undergoing Surgical Resection for High-Risk Hepatoblastoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed.
- Trial name
- NCT00077389
- Testing
- carboplatin, cisplatin, doxorubicin hydrochloride
- Where
- 24 sites in France, Ireland and 2 more
- Volunteers
- 57 people
- Sponsor
- University of Leicester
Complicated Appendicitis, Acute Appendicitis
Antibiotic Instillation in Appendicitis
Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated.
- Trial name
- NCT05470517
- Testing
- Ceftriaxone, Intra-peritoneal Fluid Aspiration
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Johns Hopkins All Children's Hospital
Colorectal Cancer
CITRuS Stage 1; Feasibility
Bowel cancer is the third most common cancer occurring in the UK. Treatment usually involves surgery, often with chemotherapy or radiotherapy.
- Trial name
- CITRuS1 (NCT04697394)
- Where
- United Kingdom
- Volunteers
- 380 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Fissure in Ano
Complex Treatment of a Chronic Anal Fissure
This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.
- Trial name
- NCT03855046
- Testing
- IncobotulinumtoxinA 50 U Intramuscular Powder for Solution, Lateral subcutaneous sphincterotomy.
- Where
- 7 sites in Russia
- Volunteers
- 340 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Quality of Life, Colorectal Cancer
Quality of Life and Survival of Patients With Colorectal Cancer 5 Years After Surgery - Follow-up of the RCT DIQOL
This observational follow-up study of the randomized trial (RCT) DIQOL investigates long-term effects of an intervention with quality of life (QoL) diagnosis and therapy on present QoL, survival, and recurrence-free survival of…
- Conditions
- Quality of Life, Colorectal Cancer, Colorectal Neoplasms, Survivorship
- Trial name
- DIQOLFollow-up (NCT04930016)
- Testing
- Quality of life diagnosis and therapy during the completed RCT DIQOL
- Where
- Germany
- Volunteers
- 208 people
- Sponsor
- Tumor Center Regensburg