Clinical trials: Complex Intervention
Loneliness
Testing a Nature-based Socila Intevention on Loneliness: the RECETAS-PRG Trial
RECETAS (Re-imagine Environments for Connection and Engagement: Testing Actions for Social Prescribing in Natural Spaces) is an European project (H2020 No 945095) that aims to reduce loneliness by linking lonely pople to…
- Trial name
- RECETAS (NCT05522140)
- Testing
- Nature-based social intervention (NBIS), Usual care + menu with nature based activities
- Where
- Czechia
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Vladimíra Dostálová
Contraception
Strengthening Contraceptive Counseling in Pakistan
High-quality contraceptive counseling can strengthen global efforts to reduce the unmet need for and suboptimal use of modern contraceptives.
- Trial name
- NCT04915885
- Testing
- Routine care, Package of contraceptive counseling interventions, Expanded methods
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nguyen-Toan Tran
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Healthy
A Study to Assess the Independent Effects of 4-Factor Prothrombin Complex Concentrate and Tranexamic Acid on Bleeding/Pharmacodynamics in Healthy Participants
The purpose of this study is to assess the independent effects of both a 4-Factor prothrombin complex concentrate (PCC) - (Kcentra) and Tranexamic acid (TXA) on the bleeding parameters (bleeding duration and blood volume)…
- Trial name
- NCT02561923
- Testing
- Rivaroxaban, Tranexamic acid, Kcentra, a 4-factor PCC
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Janssen Scientific Affairs, LLC
Prostate Cancer
Improving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Earlier work explored barriers and facilitators to accessing prostate cancer screening, particularly in underserved communities, and provided valuable insights to build upon.
- Trial name
- INCLUDE PC (NCT07407686)
- Testing
- Surveys, Semi-structured interviews and focus groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Disability Physical
Community-based Complex Intervention to Prevent Loss of Physical Function and Disability in Home-dwelling Older Adults
The aim of this study is to compare the effect of 12 weeks group-based exercise program enhanced with 24 weeks health empowerment program (HEP) to an extended usual care condition (the HEP program alone) on physical function…
- Trial name
- NCT04531852
- Testing
- CALSTI - Complex Active Lifestyle Intervention, SEMAI - Self-Management Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Survivorship, Breast Cancer
The LYSA (Linking You to Support and Advice) Trial
This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with…
- Conditions
- Survivorship, Breast Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LYSA (NCT05035173)
- Testing
- Survivorship Clinic Assessments, Survivorship Clinic Nurse Resource, Survivorship Clinic Dietitian Resource
- Where
- Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Cork
Heart Defect, Congenital, Executive Dysfunction
Executive Function Intervention for Children With Complex Congenital Heart Disease
Children with complex congenital heart disease (cCHD) nowadays survive thanks to medical advances into their teenage years and adulthood. However, many of them have difficulties with so-called executive functions.
- Trial name
- E-Fit Heart (NCT07692958)
- Testing
- E-Fit Intervention
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Bea Latal
Medication Review, Nursing Home Resident
OptiMEDs Pilot Study
Pilot study of the OptiMEDs intervention: a complex intervention for multidisciplinary medication review (including nurses, pharmacists, and physicians) in nursing homes (NH), with ICT-support for the evaluation of the…
- Conditions
- Medication Review, Nursing Home Resident, Nursing Home
- Trial name
- OptiMEDs (NCT04142645)
- Testing
- OptiMEDs
- Where
- 3 sites in Belgium
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pre-diabetes, Cardiovascular Risk Factor
Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM
Previous Icelandic studies regarding prevalence of diabetes have mostly used data from the capital area. Information on the proportion of people at risk at developing T2DM or having undiagnosed T2DM among people living in rural…
- Conditions
- Pre-diabetes, Cardiovascular Risk Factor, T2DM (Type 2 Diabetes Mellitus), Primary Health Care
- Trial name
- NCT04688359
- Testing
- Guided Self Determination
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Akureyri
Contraception, Empowerment
Strengthening Contraceptive Counseling Services: Research Protocol for a Multi-phase Complex Intervention in Pakistan and Nigeria
High-quality contraceptive counseling can strengthen global efforts to reduce the unmet need for and suboptimal use of modern contraceptives.
- Conditions
- Contraception, Empowerment, Decision Making
- Trial name
- NCT06081842
- Testing
- Contraceptive counseling strengthening intervention package
- Volunteers
- 7,920 people, healthy volunteers welcome
- Sponsor
- World Health Organization
Medication Safety, Patient Safety
Co-Development and Evaluation of a Complex Intervention to Increase Medication Safety in Nursing Homes
The study aims to develop and evaluate a new, multifaceted (complex) intervention in a mixed methods study-design to increase medication safety in nursing homes.
- Trial name
- SAME (NCT04990986)
- Testing
- Complex intervention
- Where
- Denmark
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- Anne Estrup Olesen
Social Isolation, Meals
Evaluating the RelAte Mealtime Program as an Intervention to Treat Social Isolation and Improve Cooking Behaviour Among Older Adults Living Alone
The purpose of this study is to evaluate the impact of a psychosocial and nutritional intervention, entitled "RelAte", on cooking and mealtime behaviours of older adults who are living alone and at risk of social isolation.
- Trial name
- RelAte (NCT02007551)
- Testing
- Mealtime Intervention
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Cholangiocarcinoma, Liver Fluke-Related Cholangiocarcinoma
Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand
Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer…
- Conditions
- Cholangiocarcinoma, Liver Fluke-Related Cholangiocarcinoma, Opisthorchiasis
- Trial name
- eCHEC (NCT05321992)
- Testing
- eCHEC program
- Where
- Thailand
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- McMaster University
Urinary Tract Infections
Reducing Antibiotic Prescriptions for Urinary Tract Infection in Long-Term Care Facilities
This cluster randomized controlled study evaluates the effect of a tailored observation, reflection and communication tool on used by long-term care facility staff on antibiotic prescription for urinary tract infection in…
- Trial name
- NCT03715062
- Testing
- Dialogue tool
- Where
- Denmark
- Volunteers
- 1,491 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Neck Pain, Back Pain
The Prevalence of Neck and Low Back Pain in FMSTRC Staff At the UWI Mona
The purpose of this study is to determine the prevalence of neck and low back pain among full-time staff at the Faculty of Medical Sciences Teaching and Research Complex (FMSTRC), The University of the West Indies, Mona.
- Conditions
- Neck Pain, Back Pain, Musculoskeletal Pain, Low Back Pain
- Trial name
- NCT07194746
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Adverse Childhood Experiences
The ACCEPT Study: Improving the Process of Disclosing Adverse Childhood Experiences in Community Mental Health
Experiences of abuse, neglect, domestic violence, severe bullying and community violence in childhood are very common among people who use mental health services.
- Trial name
- NCT06477380
- Testing
- ACCEPT intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Mobility Limitation, Motor Activity
Cognitive Remediation to Improve Mobility in Sedentary Seniors
The investigators propose to conduct a single-blind randomized clinical trial to test the efficacy of a computerized cognitive remediation intervention program on improving locomotion in sedentary seniors, a group at an…
- Conditions
- Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
- Trial name
- CREM (NCT02567227)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Inclusive Education
A Transferability Study on the Conditions for a Successful Inclusive Education
The investigators are conducting a realist evaluation study with a multi-case and qualitative design. The study aims to identify the conditions that promote successful students with disabilities inclusive education at school.
- Trial name
- TIAP (NCT06378307)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Video Game Addiction, Gaming Disorder
Community-Based Intervention to Reduce Problematic Video Game Use in First-Year Secondary School Students: A Cluster Randomised Controlled Trial
This cluster randomised controlled trial will evaluate whether a community-based, multicomponent intervention can reduce problematic video game use and gaming disorder among first-year secondary school students in Pontevedra…
- Trial name
- AQJ (NCT07357792)
- Testing
- Community-Based Component, Adolescent Mindfulness Component, Adult Mindfulness Component
- Where
- Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur