Clinical trials: Complex Regional Pain Syndrome (CRPS)
Complex Regional Pain Syndrome Type I
Clinical Evaluation of the Effects of Mirror Therapy in Patients With Complex Regional Pain Syndrome (CRPS) Type 1
CRPS Type 1 can occur after traumas, surgical applications or central nervous system disorders. The triggering factor in CRPS type 1 is fracture in about half of the cases.
- Trial name
- NCT03377504
- Testing
- mirror therapy, Routine physical therapy and exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ankara University
Pain, Chronic
Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults
This study is designed to test if the use of virtual reality (VR) can improve chronic pain related to CRPS. One way is to use virtual reality.
- Trial name
- NCT05888142
- Testing
- in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Washington
CRPS, Unilateral Limb Pain of Origin Other Than CRPS
The Rubber Hand Illusion (RHI) in Patients With CRPS
The present study investigates by means of the rubber hand illusion body image stability and sense of body ownership in patients with CRPS of the upper limb compared to patients with unilateral pain of origin other than CRPS and…
- Trial name
- NCT01618578
- Testing
- rubber hand illusion
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Stroke
MTPr With Shockwave on Pain & Function of SHS in Stroke
Background: shoulder-hand syndrome is considered a significant reason for the reduction of upper limb functions after stroke. Purpose: To investigate the influence of Myofascial Trigger Points (MTrPs) release and shockwave…
- Trial name
- NCT04627636
- Testing
- Myofascial trigger points pressure (MTrP) release, Shockwave therapy application, conventional therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS)
Two Point Discrimination
SPECIFIC AIMS Pain in both youth and adults is a complex, subjective and personal experience, and remains poorly understood. One particularly perplexing dimension of some forms of pain is the tendency of pain to spread outside of…
- Conditions
- Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS), Amplified Musculoskeletal Pain Syndrome (AMPS), Low Back Pain
- Trial name
- TPD (NCT03686748)
- Testing
- Two-point discrimination training, One-point discrimination training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pain
Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate the safety of hydrocodone extended-release tablets when used over a 12-month period in patients with chronic pain, as assessed by adverse events, clinical laboratory results…
- Trial name
- NCT01223365
- Testing
- Hydrocodone ER
- Where
- 54 sites in United States
- Volunteers
- 330 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Pain Syndrome, Fibromyalgia
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
This work will answer two critical questions: 1) Does intensive interdisciplinary pain treatment (IIPT) involving aerobic exercise help normalize pain processing in youth with chronic pain syndromes and 2) Are aerobic fitness…
- Conditions
- Chronic Pain Syndrome, Fibromyalgia, Chronic Headache Disorder, Functional Abdominal Pain Syndrome
- Trial name
- NCT05491499
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Boston Children's Hospital
Complex Regional Pain Syndrome, Chronic Pain
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a rare and often debilitating chronic pain condition whereby individuals may experience extreme sensitivity, discoloration, and swelling of the affected area -- along with numerous other…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I
- Trial name
- LDN-CRPS (NCT06306157)
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture
Prism Adaptation Therapy for CRPS Type 1
Complex Regional Pain Syndrome (CRPS) is a clinical condition characterized by pain that arises either without an identifiable triggering factor or with a severity disproportionate to the initiating event.
- Conditions
- Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture, CRPS (Complex Regional Pain Syndromes), Neuropathic Pain
- Trial name
- NCT07370012
- Testing
- The Prism Adaptation Therapy Group, The Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Etlik City Hospital
Complex Regional Pain Syndrome
Comparative Effects of Mirror Therapy and Standard Physiotherapy in Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by persistent pain, sensory disturbances, motor dysfunction, and functional impairment, often following trauma or surgery.
- Trial name
- (CRPS) (NCT07332884)
- Testing
- Mirror Therapy, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- University of Lahore
RSD (Reflex Sympathetic Dystrophy), Algodystrophy
Prophylactic Administration of Vitamin C in Wrist Fractures
Complex Regional Pain Syndrome or posttraumatic dystrophy is a pain syndrome which develops after a trauma, surgery or for unknown reason. The incidence after wrist fractures varies in literature from 2 - 37%.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), Algodystrophy, CRPS Type I
- Trial name
- NCT00296868
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Stichting Achmea Slachtoffer en Samenleving
Complex Regional Pain Syndrome
Treatment of Complex Regional Pain Syndrome
This study will investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) and a sensorimotor training task to treat symptoms of pain in patients with complex regional pain syndrome (CRPS).
- Trial name
- NCT05197959
- Testing
- Repetitive transcranial magnetic stimulation, Sensorimotor training
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- McMaster University
Complex Regional Pain Syndrome
Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome
The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS).
- Trial name
- LDN-CRPS (NCT02502162)
- Testing
- LDN
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Complex Regional Pain Syndromes
Comparison of Volumes of Local Anesthetics on the Efficiency and Safety of Stellate Ganglion Block for CRPS of the Arm
The purpose of this study is to compare the efficiency and safety of 2ml versus 5ml of local anesthetics used in stellate ganglion blocks for the treatment of complex regional pain syndrome of the arm.
- Trial name
- NCT03316066
- Testing
- stellate ganglion block with ropivacaine 0.2% 5 mL, stellate ganglion block wit ropivacaine 0.2% 2 mL
- Sponsor
- Maisonneuve-Rosemont Hospital
Complex Regional Pain Syndrome I of Lower Limb
"Liposomal Encapsulated Vitamin C in Complex Regional Pain Syndrome"
Abstract: Complex regional pain syndrome (CRPS) is a significant complication in operated osteoarticular pathology and may adversely affect patient's quality of life. Vitamin C is an anti-oxidant and a neuro-modulating agent.
- Trial name
- NCT04204200
- Testing
- liposomal vitamin C, standard vitamin C
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier de Ham
Stellate Ganglion Block, Cervical Epidural
Cervical Epidural and Stellate Ganglion Block in Upper Limb Complex Regional Pain Syndrome
Evaluate the efficacy of two regimens of management in relieving chronic refractory pain in patients with upper limb complex regional pain syndrome after orthopedic trauma
- Conditions
- Stellate Ganglion Block, Cervical Epidural, Complex Regional Pain Syndromes
- Trial name
- NCT05970146
- Testing
- Ultrasound guided Stellate ganglion block, unilateral cervical epidural
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Complex Regional Pain Syndrome (CRPS)
Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)
The aim of this trial was to investigate the efficacy and safety of intravenous neridronic acid in subjects with Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT03560986
- Testing
- Neridronic acid 100 mg
- Where
- 71 sites in United States, Canada and 5 more
- Volunteers
- 267 people
- Sponsor
- Grünenthal GmbH
Complex Regional Pain Syndrome (CRPS)
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Pain avoidance helps with survival. However, chronic pain patients often avoid valued life activities fearing onset or exacerbation of pain. Hence, pain avoidance no longer protects, but reduces quality of life.
- Trial name
- NCT07791966
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Transcranial Magnetic Stimulation, Complex Regional Pain Syndrome of Upper Limb (Disorder)
CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation
This is a sham controlled, randomized, double-blind, navigated repetitive Transcranial Magnetic Stimulation (nrTMS) study for the treatment of complex regional pain syndrome (CRPS types 1 and 2).
- Trial name
- NCT04439669
- Testing
- Active nrTMS and open phase
- Where
- 2 sites in Finland
- Volunteers
- 62 people
- Sponsor
- Helsinki University Central Hospital
Complex Regional Pain Syndromes
Benefit of Augmented Reality Mirror Therapy in Addition to Conventional Management in Complex Regional Pain Syndrome of the Upper Extremity
Complex Regional Pain Syndrome (CRPS) is a "polymorphic joint and periarticular pain syndrome associated with various changes in sensitivity, vasomotor, sudomotor, muscular and trophic changes".
- Trial name
- REFLEXION (NCT05787119)
- Testing
- Conventional therapy, ARMT, cortical reactivity
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes