Clinical trials: Complication
Overactive Bladder Syndrome, Detrusor Overactivity
Effect of beta3-adrenoceptor Agonist on Patients With Overactive Bladder and as a Urinary Biomarker
About one to two million women in Taiwan suffers from overactive bladder (OAB). The most commonly used anti-muscarinic drugs have a high rate of side effects.
- Trial name
- NCT04693897
- Testing
- Mirabegron 50 MG, Solifenacin Succinate 5 MG
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Ultrasound Guided Rectus Sheath Block, Pain, Postoperative
Comparison Between Ultra Sound Guided Rectus Sheath Block and Field Block for Midline Hernia Repair
Randomized double blinded controlled clinical trial will be done with a total number of 75 patients will be divided into 3 groups.
- Trial name
- NCT03225313
- Testing
- Bupivacaine Hydrochloride 0.5% Injection Solution_#4, Normal Saline Flush, 0.9% Injectable Solution_#5
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Preeclampsia, Hypotension
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Hypotension remains a common clinical problem after induction of spinal anesthesia for cesarean delivery. Maternal hypotension has been associated with considerable morbidity (maternal nausea and vomiting and fetal/neonatal…
- Trial name
- NCT00458003
- Testing
- Ephedrine, Phenylephrine
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infertility, Female, Trauma, Psychological
Adverse Childhood Experiences and Infertility : ACESI
Adverse childhood experiences can have powerful effects on health and quality of life in adulthood. Thus, having a history of childhood trauma, before the age of 18 (physical aggression, sexual abuse, death of a close person…
- Conditions
- Infertility, Female, Trauma, Psychological, Child Development, Child Abuse
- Trial name
- ACESI (NCT05952427)
- Testing
- ACE Questionnaire
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cardiovascular Complications, Leukemia
Study of Metabolic Syndrome in Adolescent and Young Adult Survivors of Childhood Leukemia Who Have Undergone Stem Cell Transplant
RATIONALE: Gathering information about how often metabolic syndrome occurs in young survivors of childhood leukemia who have undergone stem cell transplant may help doctors learn more about the disease and the long-term effects…
- Conditions
- Cardiovascular Complications, Leukemia, Long-term Effects Secondary to Cancer Therapy in Children, Metabolic Syndrome
- Trial name
- NCT00920842
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Postoperative Pain
The Efficacy of Honey on Improving the Post Surgical Course After Tonsillectomy in Children-prospective Study
The aim of this study is to investigate the effect of honey administration on pain following pediatric tonsillectomy or adenotonsilectomy.
- Trial name
- NCT03296020
- Testing
- HONEY
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Postoperative Pain, Third Molar
Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient.
- Conditions
- Postoperative Pain, Third Molar, Postoperative Complications
- Trial name
- NCT03398382
- Testing
- Magnesium tablet group, Magnesium lozenge group
- Where
- 2 sites in Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniel Jerković
Urinary Incontinence
Low-Intensity Physical Therapy for Prevention of Pre and Postpartum Urinary Incontinence
The purpose of this study is to determine if pelvic exercises can reduce the occurrence of urinary incontinence (involuntary loss of urine) before and after delivery.
- Trial name
- NCT00178282
- Testing
- Pelvic Floor Muscle exercises
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Quality of Life, Cancer of Endometrium
FitEx for Endometrial Cancer Survivors
The purpose of this study is to determine whether a physical activity tracking program called FitEx would be useful to endometrial cancer survivors.
- Conditions
- Quality of Life, Cancer of Endometrium, Behavior, Health, Self Efficacy
- Trial name
- NCT05233059
- Testing
- FitEx, Weekly Yoga Sessions, Weekly Movement Sessions
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Hemopneumothorax, Pneumothorax
Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax
The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.
- Trial name
- NCT01127880
- Testing
- Ancef or Clindamycin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Human Papillomavirus Infection
Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System
The purpose of this study is to provide data on the performance of the APTIMA HPV Assay using the TIGRIS System in detecting HPV types that may cause cervical cancer.
- Trial name
- NCT00973362
- Testing
- APTIMA HPV Assay, FDA-Approved HPV DNA Test
- Where
- 17 sites in United States
- Volunteers
- 12,896 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Preoperative Anxiety, Emergence Agitation
Association of Inflammatory Markers With Preoperative Anxiety and Agitation
This study was planned as a prospective, observational study. The study will include pediatric patients aged 3-12 who will undergo surgery.
- Trial name
- NCT06648122
- Testing
- laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Aneuploidy, Pregnancy Complications
Use of a Novel Computerized Decision Aid for Prenatal Aneuploidy Screening
The investigators aim to assess whether use of a novel, tablet-based computerized decision aid for aneuploidy screening is similar to routine care with a brief genetic counseling visit in improving patient knowledge and…
- Trial name
- DAAS (NCT02991729)
- Testing
- iPad-based decision aid, Genetic counseling appointment
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Polycystic Ovary Syndrome
History of Polycystic Ovary Syndrome in First-degree Relatives
The aim of this study was to investigate the semen analysis results of male patients with first-degree relatives meeting the diagnostic criteria for PCOS.
- Trial name
- PCOS (NCT06442228)
- Testing
- spermiogram test
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Infertility, Infertility, Female
A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte Maturation
This study will determine the rise of progesterone levels after human chorionic gonadotrophin (hCG) trigger in stimulated cycles IVF/ICSI
- Conditions
- Infertility, Infertility, Female, IVF, hCG
- Trial name
- NCT04417569
- Testing
- hCG, Ultrasound, Blood test
- Where
- United Arab Emirates
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Severe Renal Impairment
A Phase 1 Study to Assess the Effect of Severe Renal Impairment on the Pharmacokinetics, as Well as Safety/Tolerability, of Ranolazine
The purpose of this study is to assess the effect of severe renal impairment on the steady-state PK, as well as safety and tolerability, of ranolazine, compared to subjects with normal renal function.
- Trial name
- NCT01675973
- Testing
- RANEXA
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Postnatal Depression
Studies of Mothers With Postnatal Depression
This study investigates the effects of a single dose of oxytocin (OT) delivered via a nasal spray in women with and without traits of postnatal depression (PND).
- Trial name
- NCT04745494
- Testing
- OT administration
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College, London
Mrk Anomaly, Infertility, Female
Uterus Transplantation LD - Feasibility Study - Sahlgrenska - BMC
Medical know-how concerning uterus transplantation will be transferred to new site by structured process involving theory, animal workshops and a clinical feasibility study on human subjects.
- Trial name
- GOT-BMC-UTx (NCT03590405)
- Testing
- uterus transplantation surgery and IVF
- Where
- 2 sites in Sweden
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Complications, Pregnancy
Repeat Antenatal Steroids Trial
A course of steroids given to a mother who is in labor with a premature fetus will reduce the risk of the premature infant dying or having serious complications.
- Trial name
- BEARS (NCT00015002)
- Testing
- Betamethasone
- Where
- 19 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
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