Clinical trials: Complication of Hemodialysis
End Stage Renal Disease, Malnutrition
The Effect of Intradialytic Parenteral Nutrition on Nutritional Status and Quality of Life in Hemodialysis Patients
Protein-energy wasting (PEW), a hypercatabolic state characterized by loss of muscle mass and fuel reserves, is highly prevalent in hemodialysis patients.
- Conditions
- End Stage Renal Disease, Malnutrition, Sarcopenia, Hemodialysis Complication
- Trial name
- NCT04094038
- Testing
- Olimel N12, Glucose IV
- Where
- 2 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Erasmus Medical Center
Anaemia
A Study to Evaluate Efficacy and Safety of Daprodustat Compared to Darbepoetin Alfa in Japanese Hemodialysis (HD)-Dependent Subjects With Anemia Associated With Chronic Kidney Disease (CKD)
Daprodustat is a drug that is currently being developed as a treatment for renal anemia . This study is to evaluate the efficacy and safety of daprodustat following a switch from erythropoiesis-stimulating agent (ESA) in Japanese…
- Trial name
- NCT02969655
- Testing
- Daprodustat small, Daprodustat large, Darbepoetin alfa
- Where
- 50 sites in Japan
- Volunteers
- 271 people
- Sponsor
- GlaxoSmithKline
Chronic Renal Failure, Hemodialysis
Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients
The comparison between nicotinamide and sevelamer aims to demonstrate, in chronic hemodialysed patients, the non-inferiority of nicotinamide in terms of control of the phosphatemia.
- Trial name
- NICOREN (NCT01011699)
- Testing
- nicotinamide, sevelamer, cinacalcet
- Where
- 18 sites in France
- Volunteers
- 176 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
End-stage Renal Disease
Effects of Strict Volume Control in Hypertensive Hemodialysis Patients on Cardiac Structure and Chronic Inflammation
This study aims mainly to investigate the effects of two approaches to control blood pressure in hypertensive hemodialysis patients; using antihypertensive drugs versus strict volume control (by strict dietary salt restriction…
- Trial name
- NCT00307463
- Testing
- strict volume control policy, antihypertensive drugs administration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 258 people
- Sponsor
- Ege University
Chronic Kidney Diseases, Hemodialysis Complication
Exposure Of Bisphenol Analogues In Chronic Kidney Disease and Dialysis Patients
In this retrospective study, the serum levels of Bisphenol A (BPA) and three BPA analogs, namely, bisphenol B (BPB), bisphenol S (BPS), and bisphenol F (BPF), in patients with CKD, patients on dialysis therapy and healthy control…
- Trial name
- NCT04100421
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
ESRD
Assessment of Gonadal Functions in Uremic Male Patients
1. Study the prevalence of sexual dysfunction in male patients on hemodialysis aged 18-60 years (sexually active male) . 2. Study the effect of hemodialysis on the male patients sexual functions by measurement of serum prolactin…
- Trial name
- NCT04710238
- Volunteers
- 100 people
- Sponsor
- Assiut University
Staphylococcal Infections, Kidney Failure, Chronic
Study to Evaluate the Effectiveness of StaphVAX in Adults on Hemodialysis
Two part study testing the effectiveness and safety of StaphVAX vaccine in chronic hemodialysis patients against infection by Staphylococcus aureus.
- Trial name
- NCT00071214
- Testing
- S. aureus Type 5 and 8 Capsular Polysaccharide Conjugate Vaccine
- Volunteers
- 3,600 people
- Sponsor
- Nabi Biopharmaceuticals
Kidney Failure, Chronic
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
The study hypothesis is that 6 weeks of repetitive handgrip exercise will improve endothelial function and venous compliance in pre-dialysis patients with an estimated glomerular filtration rate of less than or equal to 20…
- Trial name
- NCT01068314
- Testing
- Repetitive arm exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Iowa
ESRD, Hemodialysis
The Evaluation of the DIMI RRT System In-Center to Demonstrate Safety and Usability in the Home Environment
This is a prospective, multicenter, open label, non-randomized, cross-over study. Subjects will be enrolled in the trial for approximately 18 weeks and will use the DIMI RRT System for their dialysis treatments for all study…
- Trial name
- NCT04868643
- Testing
- The DIMI Renal Replacement Therapy (RRT) System
- Sponsor
- Dialco Medical Inc.
Hemodialysis Access Failure
Three-dimensional (3D) Printed Hemodialysis Vascular Model
Infiltration of a surgically-placed hemodialysis vascular access (HVA) is recognized as a major contributor to the high hospital re-admission rate in dialysis-dependent patients.
- Trial name
- NCT05096416
- Testing
- The three-dimensional (3D) printed hemodialysis vascular model
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
End-stage Kidney Disease, CD4 T Cells
Effects of High Cut-off (HCO) Hemodialysis on Central Memory CD4+ T and Treg Cells in Patients With End-stage Kidney Disease
In this study, the investigators will evaluate whether CD4+ TCM producing effector cytokines can be distinguished on the basis of their expression of the IL-7 receptor alpha-chain (CD127).
- Conditions
- End-stage Kidney Disease, CD4 T Cells, Central Memory T Cells, Regulatory T Cells
- Trial name
- NCT01103076
- Testing
- Polyamide HD membrane
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier du Centre du Valais
Low-Level Light Therapy, Renal Insufficiency, Chronic
Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
This study aims to verify the effects of low level laser therapy (LLLT) on functional capacity, DNA damage, lower limbs muscle strength, quadriceps muscle architecture, muscle pain and perception of lower limb fatigue…
- Conditions
- Low-Level Light Therapy, Renal Insufficiency, Chronic, Renal Dialysis, Clinical Trial
- Trial name
- NCT03250715
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Chronic Renal Insufficiency, Pruritus
The Efficacy of VR and AR on Pruritus
The research will be conducted randomly in order to determine the effect of VR and AR on pruritus symptom.
- Conditions
- Chronic Renal Insufficiency, Pruritus, Itch
- Trial name
- NCT04289038
- Testing
- Autogenic Relaxation, virtual reality game application, kidney function narration
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Prevention of Thromboembolic Events
Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")
BAY2433334 is under clinical development for prevention of complications in diseases such as heart attack, irregular heart beat or stroke which can arise by formation of blood clots elsewhere in the body and travels through the…
- Trial name
- NCT04510987
- Testing
- BAY2433334 single dose in treatment groups 1-4 and 6 as well as on the dialysis free day of treatment 5, BAY2433334 on dialysis treatment day
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Bayer
Kidney Failure, Chronic
Effect of Exercise With Virtual Reality in Hemodialysis Patients
Background. An increase in inflammatory biomarkers is associated with impaired kidney function and increased cardiovascular risk and mortality.
- Trial name
- NCT05606484
- Testing
- Exercise with non-immersive virtual reality, Exercise with a static pedal
- Volunteers
- 80 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Covid19, Hemodialysis Complication
Effects of Different Dialysis Strategies on Inflammation in COVID-19 Maintenance Hemodialysis Patients
In the course of Coronavirus Disease-19 (COVID-19) uncontrolled inflammation has been related to disease severity and unfavorable outcomes.
- Conditions
- Covid19, Hemodialysis Complication, Inflammatory Response
- Trial name
- NCT04685447
- Testing
- Expanded Hemodialysis for Covid19 maintenance hemodialysis patients, Hemodialysis by protein-leaking dialyzer for Covid19 maintenance hemodialysis patients
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Universita degli Studi di Genova
Chronic Kidney Disease, Hemodialysis
Effect of Bedtime Mindfulness Meditation on Anxiety and Spiritual Well-Being in Hemodialysis Patients
This study evaluates whether Bedtime Meditation Based on Mindfulness (BM-BOM) can reduce anxiety and improve spiritual well-being in patients undergoing hemodialysis.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Anxiety, Spiritual Well-being
- Trial name
- BM-BOM (NCT07378748)
- Testing
- Bedtime Meditation Based on Mindfulness (BM-BOM), Passive Rest (Control)
- Where
- Indonesia
- Volunteers
- 58 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Hemodialysis Access Failure
Balloon-Assisted Maturation of Autogenous Arteriovenous Fistulae
Background: There are several studies that document the safety and efficacy of the balloon-assisted maturation (BAM) technique. Ultimately, there are also studies that report its possible negative consequences such as fibrosis…
- Trial name
- NCT04263116
- Testing
- Balloon Assisted Maturation
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mansoura University
ESRD, Hemodialysis Complication
Timing of Antihypertensive Medications on Key Outcomes in Hemodialysis
For patients with kidney failure requiring hemodialysis treatment, sometimes the blood pressure will drop too low during dialysis.
- Conditions
- ESRD, Hemodialysis Complication, Blood Pressure
- Trial name
- TAKE-HOLD (NCT03327909)
- Testing
- TAKE vs. HOLD
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Stanford University
Hemodialysis Complication, Shoulder Joint Disorder
The Effect of Baduanjin on Shoulder Function in Maintenance Hemodialysis Patients
The aim of this study is to examine the effect of 18-month Baduanjin exercise on shoulder joint function in maintenance hemodialysis (MHD) patients.
- Conditions
- Hemodialysis Complication, Shoulder Joint Disorder, CKD-MBD
- Trial name
- NCT06314321
- Testing
- Baduanjin exercise
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
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