Clinical trials: Complication of Infusion
Healthy, Polyuria-polydipsia Syndrome
Copeptin After Arginine Infusion in Polyuria-Polydipsia Syndrome
the purpose of the study is to investigate whether arginine infusion is a new tool to differentiate patients with diabetes insipidus, primary polydipsia and healthy subjects.
- Trial name
- NCT01879137
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Pulmonary Complications, Intra-abdominal Infection
The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI
The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The…
- Trial name
- PPCs (NCT06304779)
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Zhongshan Hospital
Lung Cancer(Primary, Metastatic), Benign Lung Mass Requiring Operation
The Impact of Intraoperative Systemic Lidocaine Infusion on Chronic Postoperative Pain After Video-assisted Thoracic Surgery (VATS)
Systemic lidocaine infusion may improve the patients' chronic post surgical pain after video-assisted thoracic surgery
- Trial name
- NCT02006966
- Testing
- Systemic intravenous lidocaine infusion, Normal saline infusion
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Yonsei University
Cholelithiases, Appendicitis
Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements
Lignocaine is a local anaesthetic that is widely used in all medical and surgical fields. Many clinical studies have shown that intravenous (IV) lignocaine given in the perioperative period was safe, reduced airway complications…
- Conditions
- Cholelithiases, Appendicitis, Ovarian Cysts
- Trial name
- NCT06064331
- Testing
- Lignocaine
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Surgical Procedure, Unspecified, Pain, Postoperative
Continuous Infusions vs Scheduled Bolus Infusions
The goal of the study is to compare continuous infusions and scheduled bolus infusions for peripheral nerve blocks and their effect on post-surgical pain.
- Trial name
- NCT03230565
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Stanford University
The Patients With Gastric Cancer Who Are Scheduled to Receive Laparoscopy Assisted Gastrectomy
Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
Fentanyl based intravenous patient controlled analgesia(PCA)is popular method for postoperative pain control, but information regarding optimal dose of fentanyl in IV PCA is currently lacking.
- Trial name
- NCT01863355
- Testing
- B0 group: bolus 0.6mcg/kg without background infusion, BL group: bolus 0.4mcg/kg with background infusion rate 0.2mcg/kg/hr, BH group: bolus 0.2mcg/kg with background infusion rate 0.4mcg/kg/hr
- Where
- South Korea
- Volunteers
- 225 people
- Sponsor
- Yonsei University
Surgical Site Infection (SSI)
Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During CABG Surgeries in Egyptian Patients.
A randomized controlled trial on adults who underwent coronary artery bypass grafting (CABG) surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT)…
- Trial name
- NCT07658378
- Testing
- Cefazolin 2 g Infusion, Cefazolin 2 GM Injection
- Volunteers
- 100 people
- Sponsor
- Helwan University
Pain, Postoperative
Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section
Patients experience considerable amount of pain after cesarean section. The aim of this study is to investigate the effect of tramadol (an opioid pain killer) added to levobupivacaine (a local anesthetic) in continuous wound…
- Trial name
- NCT01916915
- Testing
- Tramadol infusion via wound catheter, Levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ufuk University
Postoperative Hypoalbuminemia, Postoperative Complications
Effect of Goal-Oriented Albumin Infusion on Postoperative Complication Management in Gastric Cancer Surgery
This study aims to evaluate the impact of goal-oriented albumin infusion on short-term postoperative outcomes in gastric cancer patients. It is a single-center, prospective, non-randomized controlled study.
- Conditions
- Postoperative Hypoalbuminemia, Postoperative Complications, Gastric Cancer
- Trial name
- GOAI (NCT07119463)
- Testing
- Human Serum Albumin Infusion for LAT Group, Human Serum Albumin Infusion for HAT Group
- Where
- China
- Volunteers
- 112 people
- Sponsor
- The First Hospital of Jilin University
Hip Surgery, Postoperative Pain Management
Comparison of Intermittent Bolus vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery
This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip…
- Conditions
- Hip Surgery, Postoperative Pain Management, Pericapsular Nerve Group Block (PENG Block), Regional Anesthesia
- Trial name
- ICPENG (NCT06834243)
- Testing
- Intermittent Bolus PENG Block, Continuous Infusion PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Onur Baran
Catheter Complications, Thrombosis
Comparison Between Sutureless Devices for PICC and a New System KT FIX PLUS
PICC (Peripherally Inserted Central Catheter) are commun used. Just one paper report morbidity with suture as fixation system for PICC (dislodgement, infection) In the guidelines it's recommended to use sutureless device.
- Conditions
- Catheter Complications, Thrombosis, Displacement of Infusion Catheter, Quality of Life
- Trial name
- KTFIXPICC (NCT02805335)
- Testing
- KTFIX PLUS
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Sarcoma, Melanoma
Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
The purpose of this study is to evaluate the safety and tolerability of different doses and administration regimens of Stimotimagene copolymerplasmid in patients with histologically confirmed diagnosis of solid tumor and/or its…
- Conditions
- Sarcoma, Melanoma, Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms
- Trial name
- NCT05578820
- Testing
- Stimotimagene copolymerplasmid, Ganciclovir
- Where
- 4 sites in Russia
- Volunteers
- 21 people
- Sponsor
- Gene Surgery LLC
Anxiety, Postoperative Pain
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
Dexmedetomidine is a drug known for its pain-relieving and restlessness-reducing effects. The purpose of this run is to use the association between this use during surgery and the attrition of post-operative pain and discomfort.
- Conditions
- Anxiety, Postoperative Pain, Bleeding
- Trial name
- NCT05986942
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Burak Omur
Heart Failure, Renal Dysfunction
Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction
The purpose of the study is to determine if low doses of BNP can improve renal function in people with chronic heart failure with renal dysfunction, also to determine whether Sildenafil assists with improvement.
- Trial name
- Aim 3 BNP/PDEV (NCT00972569)
- Testing
- BNP and PDE-V, BNP
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postpartum Hemorrhage
Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Patients having Cesarean section after they have been in labor for many hours bleed much more, in average twice as much, as compared with patients having an elective Cesarean section.
- Trial name
- NCT01869556
- Testing
- Oxytocin, Ergot, Carboprost
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postoperative Pain
Continuous Subpleural Infusion of Bupivacaine
Rationale: For the past 3 years the investigators have routinely used an axial subpleural tunneling technique that del Study Design: All patients over the age of 18 having an isolated thoracoscopic procedure performed at Inova…
- Trial name
- NCT01566838
- Testing
- Subpleural pain catheter with infusion of 0.125% bupivacaine, Standard acute pain management
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Inova Health Care Services
Pain, Postoperative, Pain, Acute
Lidocaine and Magnesium and Ketamine in Gynecological Surgery
The aim of this study will be to investigate the effect of a combination of intravenous infusions of lidocaine and magnesium versus a combination of intravenous infusions of lidocaine and ketamine versus an intravenous infusion…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- annie-sophia (NCT04622904)
- Testing
- lidocaine-magnesium infusion, lidocaine-ketamine infusion, lidocaine infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Perimenopausal Disorder, Menopause
Inovium Ovarian Rejuvenation Trials
The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause…
- Conditions
- Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions
- Trial name
- NCT03178695
- Testing
- Autologous PRP injection into human ovarian tissue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascendance Biomedical
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Preliminary Exploration on the Operational Standards of Insulin Pump Installation in Diabetes Clinic in China
Continuous subcutaneous insulin infusion (CSII), known as insulin pump therapy, has been widely used for diabetes patients in recent years.
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Gestational Diabetes Mellitus, Pancreatogenic Diabetes Mellitus
- Trial name
- NCT04129424
- Testing
- Insulin pump (Microtech, Equil®)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Peking Union Medical College Hospital