Clinical trials: Complication of Ventilation Therapy
Mechanical Ventilation Complication, Muscle Weakness Condition
Effects of NMES in Critically Ill Patients
Muscle wasting occurred early and rapidly in critically ill patients. Early therapeutic strategies to either maintain muscle structure and function should be encouraged.
- Conditions
- Mechanical Ventilation Complication, Muscle Weakness Condition, Covid19
- Trial name
- NUMBERNMES (NCT04382378)
- Testing
- neuromuscular electrical stimulation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Escola Superior de Ciencias da Saude
Ventilation Therapy; Complications
Post Market, Prospective Multicenter Observational Study of the Safety and Performance of Bellavista Ventilator
This prospective post market clinical follow up (PMCF) study will evaluate the safety and performance of bellavista ventilator and the iFlow sensors in daily clinical routine.
- Trial name
- NCT05383651
- Testing
- bellavista 1000, bellavista 1000 neo
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 350 people
- Sponsor
- Vyaire Medical
Kidney Diseases
Effects of Virtual Reality and Breathing Exercises on Hemodialysis Patients' Symptoms and Quality of Life
Purpose: This study aims to examine the effects of virtual reality glasses and breathing exercises on symptoms and quality of life in patients receiving hemodialysis treatment.
- Trial name
- NCT06968130
- Testing
- routine hemodialysis, Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Trakya University
Preeclampsia, Hypertension
CPAP in Preeclampsia
Study design: Single blinded randomised control trial Planned sample size: 30 (women randomized 2:1 to receive either CPAP or no CPAP) Objectives: Primary objective: Assess the effects of nasal CPAP on sleep physiology, 24 blood…
- Trial name
- NCT02303834
- Testing
- Continuous Positive Airway Pressure Ventilation (CPAP)
- Where
- 2 sites in Australia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Respiration; Insufficient or Poor, Newborn, Infant,Premature
Comparison of Leakage With Nasal Prongs and Nasal Mask Interface in Newborns Receiving CPAP Treatment
The study is a two-armed randomized cross-over comparison of leakage with nasal prongs and nasal mask interface in newborn infants treated with CPAP, born after 28 weeks of gestational age.
- Trial name
- ToNIL (NCT03586856)
- Testing
- Nasal mask interface, Nasal prongs interface
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Baldvin Jonsson
Complication of Ventilation Therapy
Prevention of Gastric Insufflation During Positive Pressure Ventilation ?
Evaluation of a new method to prevent gastric insufflation
- Trial name
- NCT03378583
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University of Liege
Lymphedema, Breast Cancer, Lymphedema of Upper Limb
Does Inclusion of Diaphragmatic Breathing Exercises in Complete Decongestive Therapy Provide Further Benefits in Patients With Breast Cancer Related Lymphedema
Complete decongestive therapy is proven to be effective in reducing lymphedema related symptoms such as swelling and pain. Breathing exercises, on the other hand, may also help managing lymphedema symptoms.
- Trial name
- NCT05754346
- Testing
- Complete Decongestive Therapy, Upper extremity exercises combined with diaphragmatic breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Bakircay University
Extubation Failure, Prematurity
Comparing HHHFNC and nCPAP Ventilation Methods for the Prevention of Extubation Failure in Preterm Infants
Purpose is to show that HHHFNC method is as effective and safe as nCPAPand even more comfortable than it as non-invasive respiratory support for the prevention of extubation failure in preterm with gestational age of 26-32 weeks.
- Trial name
- NCT02887846
- Testing
- Heated Humidified High-Flow Nasal Cannula
- Volunteers
- 200 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Gestational Diabetes, Sleep Apnea
Sleep Apnea and Gestational Diabetes
The investigators hypothesize that pregnant women with gestational diabetes will have a high incidence of sleep apnea, and that the treatment of sleep apnea will lead to improved glucose control in these women.
- Trial name
- NCT02108197
- Testing
- Continuous positive airway pressure (S9, ResMed)
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Ramathibodi Hospital
ARDS, Human, Ventilation Therapy; Complications
Assessment of the Hemodynamic Effects of PEEP According to Alveolar Recruitment During the ARDS
The corner stone of the treatment of ARDS is mechanical ventilation with high levels of positive end-expiratory pressure, also called PEEP. A high level of PEEP is recommended and frequently used.
- Conditions
- ARDS, Human, Ventilation Therapy; Complications, Alveolar; Disorder
- Trial name
- NCT05524558
- Testing
- Pulmonary artery catheter, Esophagal pressure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Bicetre Hospital
Ventilator Lung, Liver Cirrhosis
Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy
This randomized controlled study's objective is to find a safer mechanical ventilation strategy to reduce intraoperative bleeding in liver cancer patients undergoing laparoscopic major liver resection.
- Conditions
- Ventilator Lung, Liver Cirrhosis, Hepatocellular Carcinoma, Blood Loss, Surgical
- Trial name
- NCT05490147
- Testing
- conventional tidal volume (tidal volume [ml]= ideal body weight [kg]* 10~12) group, low tidal (tidal volume [ml]= ideal body weight [kg] * 6~8) volume
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Diaphragm Injury, Pathology
Effects of Mechanical Ventilation on the Diaphragm in COVID-19 Intensive Care Patients. A Post-mortem Pathology Study
The diaphragm is the fundamental muscle of the respiratory system. The diaphragmatic dysfunction is present in 60% of critical patients at hospital admission and up to 80% after prolonged mechanical ventilation and difficult…
- Conditions
- Diaphragm Injury, Pathology, COVID-19 Acute Respiratory Distress Syndrome, Ventilation Therapy; Complications
- Trial name
- NCT05191433
- Where
- 2 sites in Italy
- Volunteers
- 41 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Little Lungs Study
This clinical trial is being done to evaluate the safety and clinical response of late surfactant treatment with budesonide in extremely preterm infants requiring mechanical ventilation at 7-14 days of age.
- Trial name
- NCT06855043
- Testing
- Calfactant, Budesonide
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Ventilation Therapy; Complications, Ventilator-Induced Lung Injury
Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK)
The primary objective of this prospective observational physiological study is to evaluate the variation in regional distribution of intrapulmonary volume in the dependent and non-dependent lung regions in patients undergoing…
- Trial name
- SPARK (NCT06448988)
- Testing
- Park Bench position
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Intubation, Intratracheal, Critical Illness
Post-extubation Assessment of Laryngeal Symptoms and Severity
The goal of this study is to learn more about voice and airway problems that patients experience during and after the time patients have an oral endotracheal tube in patients' airway to help patients breathe while receiving…
- Conditions
- Intubation, Intratracheal, Critical Illness, Mechanical Ventilation Complication, Complication of Ventilation Therapy
- Trial name
- PALSS (NCT03726086)
- Testing
- laryngoscopy
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea, Delayed Emergence From Anesthesia
Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea
The purpose of this study is to determine whether modafinil use in patients with obstructive sleep apnea will improve postoperative delayed emergence after general anesthesia.
- Trial name
- ModOSA (NCT02494102)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Ventilation Therapy; Complications
Ultrasound Evaluation of Abdominal Muscle Thickness During Mechanical Ventilation
Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle…
- Trial name
- ABDO-VM (NCT04939298)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier de Roanne
End Stage Renal Disease, Chronic Kidney Disease
Comparison of Dialysis Therapies on Cognitive Function
This study will evaluate the effects of more frequent dialysis on cognitive function including the assessment of sleep apnea and restless legs.
- Trial name
- NCT00597103
- Testing
- Cognitive Function Testing-10 Tests, Sleep Assessment Testing, Periodic Leg Movement Syndrome Assessment
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Satellite Healthcare
Severe Burns, Acute Kidney Injury
Association of Continuous Renal Replacement Therapy With Mortality and Length of Stay in Critically Burned Patients
This retrospective observational study aims to investigate the clinical outcomes of critically ill burn patients who underwent continuous renal replacement therapy (CRRT).
- Conditions
- Severe Burns, Acute Kidney Injury, Critical Illness
- Trial name
- CRRT-BURN (NCT07195565)
- Where
- Turkey (Türkiye)
- Volunteers
- 238 people
- Sponsor
- Pinar Timur Tasci