Clinical trials: Complications, Postoperative
Lumbar Spine Surgery
Safety and Efficacy of DepoDur in Lumbar Spine Surgery Patients
The purpose of the study is to help determine the appropriate dose of DepoDur for use in spinal surgery. The study will also assess the safety of this drug in this patient population.
- Trial name
- DepoDur (NCT00335517)
- Testing
- DepoDur
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Rochester
Postsurgical Pain
Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
Total knee arthroplasty is a surgical treatment which involves replacing the damaged articular cartilage of the knee joint with an artificial prosthetic in end-stage knee osteoarthritis.
- Trial name
- MP-TKA (NCT06202989)
- Testing
- Multiprofen-CC™ plus standard treatment
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- KAZM Pharmaceuticals Inc.
Obesity, Postoperative Pain
Laparoscopic Bariatric Surgery and Erector Spinae Plane Block
The aim of the study is to evaluate the effect of erector spinae plane (ESP) block on postoperative analgesic consumption in patients undergoing laparoscopic bariatric surgery
- Conditions
- Obesity, Postoperative Pain, Bariatric Surgery
- Trial name
- NCT04189289
- Testing
- ESP block group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Antalya Training and Research Hospital
Postoperative Complications, Operative Time
Eliminating Learning Curve Related Morbidity in Fast Track Laparoscopic Roux-en-Y Gastric Bypass
Background: Laparoscopic Roux en Y gastric bypass (LRYGB) is associated with a significant learning curve. We report the results of a systematic training programme from a high volume bariatric center measuring the outcome by…
- Conditions
- Postoperative Complications, Operative Time, Surgical Volume
- Trial name
- NCT01257789
- Testing
- laparoscopic gastric bypass
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Private Hospital Moelholm
Cesarean Section, Exercise Therapy
Effectiveness Of Early Bed Mobility Exercises And Ambulation In Post Operative Cesarean Section Pain Reduction
This study aims to evaluate the effectiveness of early bed mobility exercises and ambulation in reducing post-operative pain among women who undergo elective cesarean section.
- Conditions
- Cesarean Section, Exercise Therapy, Early Ambulation
- Trial name
- NCT07501390
- Testing
- Early Bed Mobility Exercises and Ambulation, Routine Nursing Care
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Lady Reading Hospital, Pakistan
Phantom Limb Pain After Amputation, Chronic Pain Due to Injury
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT).
- Conditions
- Phantom Limb Pain After Amputation, Chronic Pain Due to Injury, Postoperative Pain, Trauma (Including Fractures)
- Trial name
- NPWT-Pain Stud (NCT07475897)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Mastectomy, Breast Cancer
Comparing the Quality of Analgesia With Pectoral Nerve Block and Serratus Plane Block in Modified Radical Mastectomy
The use of pectoral nerve block (PECSB) is a new technique during modified radical mastectomy MRM. The Serratus anterior Plane (SAP) Block has been proven to be an effective component of multimodal analgesia regimens for a…
- Trial name
- NCT05224310
- Testing
- PECS block, SAP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Emergence Agitation
Small Doses of Dexmedetomidine for Emergence Agitation
Dexmedetomidine Hydrochloride is a kind of high selectivity alpha 2 agonists adrenaline, can inhibit the activity of sympathetic nerve, and reduce the adverse effects of stress reaction in anesthesia recovery period.Literatures…
- Trial name
- NCT02169843
- Testing
- Sevoflurane, Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tang-Du Hospital
Post Surgical Pain, Surgery
Mindfulness Surgical Pain Outcomes
This will be a prospective randomized study to evaluate novel, clinically feasible, easily deliverable, pragmatic ways of preemptively modifying known CPSP and behavioral risk factors for acute to chronic pain transitions in…
- Trial name
- MNF (NCT05838443)
- Testing
- Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gynecologic Disease
the Effect of Dexmedetomidine and Licodaine on Acute Postoperative Pain in Gynecological Laparoscopy
The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy
- Trial name
- NCT04906889
- Testing
- Dexmedetomidine Hydrochloride, Remifentanil Hydrochloride, Lidocaine Hydrochloride
- Where
- 2 sites in South Korea
- Sponsor
- The Catholic University of Korea
Pain, Postoperative Pain
A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
Post-operative, throat pain, nausea and vomiting is a common occurrence in rhinology surgeries due to the use of throat packs during the procedure.
- Conditions
- Pain, Postoperative Pain, Bleeding, Nose Bleed
- Trial name
- NCT03678168
- Testing
- Throat Pack, Pharyngeal Tampons
- Where
- Bahrain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
ST Elevation Acute Myocardial Infarction
Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients
Infarct size is a major determinant of prognosis after Acute Myocardial Infarction (AMI). The investigators recently reported that cyclosporine A, when administered immediately prior to percutaneous coronary intervention (PCI)…
- Trial name
- CIRCUS (NCT01502774)
- Testing
- Injection of Cyclosporin, Echocardiography
- Where
- 45 sites in Belgium, France and 1 more
- Volunteers
- 970 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Acute
Comparative Study Between Caudal Epidural Block and Bilateral Erector Spinae Plane Block in Lumbosacral Spine Surgeries.
It is widely believed that major lumbosacral spine surgeries are associated with severe postoperative pain that may delay the functional recovery of the patient.
- Trial name
- NCT05729308
- Testing
- caudal epidural block, bilateral erector spinae plane block, general anesthesia with intravenous analgesia.
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Chronic Post Surgical Pain, Functional Recovery
Incidence of Chronic Pain in Patients Undergoing Knee Arthroplasty Within a Fast-Track Protocol
The goal of this study is to learn about pain after knee replacement surgery. The surgery uses a fast-recovery program called Enhanced Recovery After Surgery (ERAS).
- Conditions
- Chronic Post Surgical Pain, Functional Recovery, ERAS, Chronic Opioid Use
- Trial name
- NCT07673276
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- University Hospital, Ghent
Cardiac Arrest (CA), Post Cardiac Arrest Syndrome
Survival After Cardiac Arrest: How New Treatment Guidelines Changed Patient Outcomes.
The goal of this retrospective observational cohort study is to evaluate whether the progressive implementation of updated post-cardiac arrest care guidelines has improved survival and neurological recovery in adult patients…
- Trial name
- RetroAC (NCT07649889)
- Testing
- post-resuscitation care
- Where
- Italy
- Volunteers
- 630 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Myocardial Reperfusion Injury
Delayed Postconditioning
The investigators previously reported that angioplasty postconditioning reduces infarct size (cardiac enzyme release) in STEMI patients with a fully occluded coronary artery at hospital admission.
- Trial name
- PRIME (NCT01483755)
- Testing
- Postconditioning, Percutaneaous intervention
- Where
- 5 sites in France
- Volunteers
- 72 people
- Sponsor
- Hospices Civils de Lyon
Open Heart Surgery, Postoperative Pain
Postoperative Pain Alleviation in Open Heart Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT03106818
- Testing
- bupivacain with magnesium sulphate, Bupivacaine only, conventional
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Analgesia, Post Operative Pain
Effects of Scalp Nerve Block on Postoperative Pain, Hemodynamics and Surgical Stress Response in Craniotomy Surgery
The hypothesis of this study is that preincisional scalp nerve block will reduce postoperative opioid use and surgical stress response compared to postincisional scalp nerve block in craniotomy surgery with general anesthesia.
- Trial name
- NCT06748547
- Testing
- scalp nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Umraniye Education and Research Hospital
Hemorrhage, Surgical, Myoma;Uterus
Comparison Effectiveness of Rectal Misoprostol & Intravenous Tranexamic Acid Reducing Hemorrhage in Myomectomy
Fibroids are the most commonly encountered tumors in the female reproductive system. In patients, fibroids most often lead to abnormal uterine bleeding and the resulting anemia.
- Conditions
- Hemorrhage, Surgical, Myoma;Uterus, Effect of Drug, Postoperative Hemorrhage
- Trial name
- NCT06114758
- Testing
- Cytotec 200Mcg Tablet, Transamine
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ankara Etlik City Hospital
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