Clinical trials: Comprehensive Care
Stroke, Stroke, Ischemic
Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Stroke Care
Stroke is the 5th leading cause of death and the leading cause of adult disability in the United States (US). Stroke is a complex disease with multiple interacting risk factors (including genetic, high blood pressure and…
- Conditions
- Stroke, Stroke, Ischemic, Stroke, Acute, Stroke Sequelae
- Trial name
- C3FIT (NCT04000971)
- Testing
- Integrated Stroke Practice Unit, Comprehensive or Primary Stroke Center
- Where
- 21 sites in United States
- Volunteers
- 1,196 people
- Sponsor
- Vanderbilt University Medical Center
Infertility, Artificial Intelligence (AI)
Infertility Treatment
The primary objective of this project is to increase the treatment compliance and success of infertile couples based on the Knowledge-Motivation-Behavioral Skills model.
- Trial name
- ınfertilitech (NCT06960551)
- Testing
- ınfertility group, control group
- Volunteers
- 148 people
- Sponsor
- Inonu University
Lung Cancer, Gastro-intestinal Cancer
The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person
Phase 2 randomized controlled study using a waitlist control group. The study also has a single arm pre-post test 12-week chair-based exercise arm for those who have received the geriatric assessment in the older adults with…
- Conditions
- Lung Cancer, Gastro-intestinal Cancer, Genito-Urinary Cancer, Breast Cancer
- Trial name
- SOAR (NCT05509751)
- Testing
- GAM, exercise, health education, online chair-based exercise combined with health education
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Martine Puts
Rare Cancer
Treatment Guided by Comprehensive Genome and Transcriptome Analysis Versus Standard of Care in Advanced Rare Cancers
Rare cancers, defined by an incidence of fewer than 6 cases per 100,000 persons per year, constitute nearly 25% of adult malignancies.
- Trial name
- RATIONALE (NCT06855134)
- Where
- 16 sites in Germany
- Volunteers
- 946 people
- Sponsor
- German Cancer Research Center
Depressive Disorder, Major
54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide
The purpose of the study is to evaluate the efficacy of intranasal esketamine 84 milligram (mg) compared with intranasal placebo in addition to comprehensive standard of care in reducing the symptoms of Major Depressive Disorder…
- Trial name
- Aspire I (NCT03039192)
- Testing
- Esketamine, Standard of Care
- Where
- 56 sites in United States, Bulgaria and 9 more
- Volunteers
- 226 people
- Sponsor
- Janssen Research & Development, LLC
Thyroid Diseases, Goiter
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues.
- Conditions
- Thyroid Diseases, Goiter, Thyroid Neoplasms
- Trial name
- NCT07575243
- Testing
- Enhanced Recovery After Surgery protocol, Conventional perioperative care
- Where
- Egypt
- Volunteers
- 143 people
- Sponsor
- Assiut University
Geriatric Syndrome
Expanding Access to Comprehensive Geriatrics Care Via Telehealth
The overall objective of the TeleGRACE project is to improve the care and outcomes of older Veterans with a recent inpatient stay by expanding access to the evidence-based GRACE program, by evaluating a telehealth implementation.
- Trial name
- TeleGRACE (NCT05166603)
- Testing
- TeleGRACE
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- VA Office of Research and Development
Anxiety
Management of Anxiety in Intensive Care Unit Including Olfactotherapy
The OCEAN observational study is a pilot study. The aim is to validate the interest of the intervention of essential oils, relaxing music and dim light on the anxiety of patient who are in the intensive care unit.
- Trial name
- OCEAN (NCT04210635)
- Testing
- ZEN cart
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Laboratoires Arkopharma
Ischaemic Heart Disease
SheppHeartCABG - Phase One Rehabilitation After Coronary Artery Bypass Grafting
Background: Patients undergoing coronary artery bypass graft surgery often experience a range of problems and symptoms related to the procedure and the underlying heart disease.These problems include anxiety and depressive…
- Trial name
- SheppHeart (NCT02290262)
- Testing
- Comprehensive phase one rehabilitation
- Where
- Denmark
- Volunteers
- 326 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ischaemic Heart Disease, Cardiac Arrhythmia
Effects of a Comprehensive Sexual Rehabilitation Programme in Heart Patients
The objective is to investigate the effect of a comprehensive sexual rehabilitation program, consisting of a psycho-educative component and a physical exercise component.
- Conditions
- Ischaemic Heart Disease, Cardiac Arrhythmia, Sexual Dysfunction
- Trial name
- CopenHeartSF (NCT01796353)
- Testing
- sexual rehabilitation, Usual care
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Eye Disease, Eye Care
Project inCharge: Increasing the Rate of Comprehensive Eye Care Utilization by Older African Americans Through Community-Based Eye Health Education Program
The study design is a randomized intervention evaluation. Ten senior centers in predominately African American communities in the Birmingham, Alabama will be selected as sites for the educational intervention.
- Conditions
- Eye Disease, Eye Care, Vision
- Trial name
- inCharge (NCT00591110)
- Testing
- Eye care education, Social-contact control
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
Effect of a Tailored Program of Physical Activity and Nutritional Counseling on Fatigue Reduction in Breast Cancer Patients Receiving an Adjuvant Treatment
Cancer-related fatigue is by far the most common symptom affecting cancer patients. Combining regular dietary counseling and tailored physical activity is associated with reduced cancer-related fatigue and can improve quality of…
- Trial name
- APAD (NCT01495650)
- Testing
- Tailored program of PA and nutritional counseling
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Frailty
Comprehensive Geriatric Assessment in Primary Care: A Randomised Feasibility Trial
The study aims to explore feasibility of implementing a tailored CGA to older adults with frailty and evaluate staff and patients perception of the intervention. In line with this, the objectives of the study are: 1.
- Trial name
- NCT03394534
- Testing
- CGA group
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Derby
Lung Neoplasm, Thoracic Surgical Procedures
Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients
This multicenter prospective clinical study focuses on elderly patients with lung cancer. The investigators will build a standardized clinical registry database, develop perioperative risk stratification and surgical…
- Conditions
- Lung Neoplasm, Thoracic Surgical Procedures, Perioperative Care, Postoperative Rehabilitation
- Trial name
- NCT07632664
- Testing
- Pulmonary Lobectomy plus Mediastinal Lymph Node Sampling, Pulmonary Segmentectomy plus Mediastinal Lymph Node Sampling, Pulmonary Wedge Resection plus Mediastinal Lymph Node Sampling
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University People's Hospital
Pharmacists in Geriatric Health Services, Conditions Unspecified
The Pharmacist in the Acute Geriatric Inpatient Treatment Team
This trial investigates the effects of a comprehensive pharmaceutical assessment in an acute care geriatric hospital on the number of hospital readmissions and patient's days spent at home.
- Trial name
- AGITATE (NCT03412903)
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Prof. Dr. med. Cornelius Bollheimer
Cognitive Rehabilitation, Physical Rehabilitation
Intensive Cognitive and Physical Rehabilitation Program
This will be a feasibility study. Individuals that have undergone an evaluation day at the center for successful aging with diabetes with a Glycosylated hemoglobin (A1C) of >=7.5 and a Montreal Cognitive Assessment (MoCA)<26 will…
- Trial name
- NCT02764905
- Testing
- intensive cognitive physical rehabilitation program
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Major Depressive Disorder With Suicidal Ideation With Intent
Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent
Study of efficacy and safety of MIJ821 in addition to comprehensive standard of care on the rapid reduction of symptoms of Major Depressive Disorder (MDD) in subjects who have suicidal ideation with intent
- Trial name
- NCT04722666
- Testing
- MIJ821 Intravenous Injection
- Where
- 39 sites in United States, Argentina and 12 more
- Volunteers
- 199 people
- Sponsor
- Novartis Pharmaceuticals
Lung Neoplasms
DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns
This is a prospective, observational, multicenter study, in which clinical and demographic data will be extracted from medical records.
- Trial name
- DeniLA (NCT07109154)
- Where
- 7 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center