Clinical trials: Computed Tomography, active
Prostate Cancer
Photon-Counting Computed Tomography-Based Urethral Visualization Without Catheterization for Radiotherapy Planning: A Prospective Pilot Study Under ANTHEM
In prostate cancer radiotherapy, it is important to accurately identify and protect healthy organs near the prostate. One of these structures is the urethra, the tube that carries urine from the bladder out of the body.
- Trial name
- PURE-CT/ANTHEM (NCT07730203)
- Testing
- image acquisition
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Clinico Humanitas
Coronary Disease
Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial
The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization
- Trial name
- PERFUSERCT (NCT02208388)
- Testing
- computed tomography perfusion guided treatment, Fractional flow reserve guided treatment
- Where
- 7 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Young-Hak Kim, MD, PhD
Prostate Cancer, Localized Prostate Carcinoma
Erectile Function PRESERVation in Definitive Radiotherapy for Prostate Cancer by MRI-Enhanced Adaptive Sparing of the Neurovascular Bundle
Radiotherapy is a standard and highly effective treatment for prostate cancer that is confined to the prostate gland. One modern approach, called stereotactic body radiotherapy (SBRT), delivers treatment in just five sessions and…
- Conditions
- Prostate Cancer, Localized Prostate Carcinoma, Low-Risk Prostate Cancer, Intermediate-risk Prostate Cancer
- Trial name
- EF-PRESERVE (NCT07916779)
- Testing
- Daily Adaptive MR-Enhanced SBRT with Neurovascular Bundle Sparing
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- University of Zurich
Lung Cancer
Integrating Artificial Intelligence Into Lung Cancer Screening.
Lung cancer (LC) screening using low-dose chest CT (LDCT) has already proven its efficacy. The mortality reduction associated with LC screening is around 20%, much higher than the reduction in mortality associated with screening…
- Trial name
- DACAPO (NCT05704920)
- Testing
- IA, Not IA
- Where
- France
- Volunteers
- 2,722 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Ischemic Stroke
Recombinant Human Prourokinase for Acute Ischemic Stroke in the Extended Window Selected by CT-Based Artificial Intelligence
This multicenter, prospective, randomized, double-blind, placebo-controlled trial aims to evaluate the efficacy and safety of intravenous recombinant human prourokinase (rhPro-UK) in patients with acute ischemic stroke treated…
- Trial name
- RAISE-AI (NCT07901842)
- Testing
- Recombinant Human Prourokinase for Injection (rhPro-UK)
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Thin Labial Plate
Long-Term Bone Dimensional Changes Following Flapless Immediate Implant Placement
Nowadays, achieving long-term hard tissue stability is the definitive goal of a successful immediate implant placement and has become the optimal challenge for clinicians over the past few decades.
- Trial name
- NCT07813494
- Testing
- IIP+Bone graft + CHA, IIP +CHA only
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- International Dental Contiuing Education
Lung Cancer Screening, Tobacco Use Disorder
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA…
- Conditions
- Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
- Trial name
- NCT07576595
- Testing
- Smoking cessation multilevel Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Pyrexia
Comparison of FDG-PET/CT and CECT-CAP as Upfront Imaging Modality for the Diagnosis of Pyrexia of Unknown Origin
Pyrexia of unknown origin (PUO) remains one of the most challenging diagnostic problems in modern medicine. Despite advances in laboratory diagnostics, microbiological techniques, imaging modalities, and molecular testing, a…
- Trial name
- CET-PET-PUO (NCT07816783)
- Testing
- FDG-PET, CECT, Standard care of therapy
- Where
- India
- Volunteers
- 132 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Ovarian Cancer, Ovarian Tumor
AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery
The goal of this observational study is to learn if a computer program can tell what type of ovarian tumour a person has from a CT scan taken before surgery. The program uses artificial intelligence (AI).
- Conditions
- Ovarian Cancer, Ovarian Tumor, Borderline Ovarian Tumor
- Trial name
- OvaClass (NCT07883551)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cardiopulmonary Arrest, VA-ECMO
Optimized CT-imaging Protocol in VA-ECMO Patients After CPR
Veno-arterial (VA) extracorporal membrane oxygenation (ECMO) is an increasingly applied method in patients under cardiopulmonary resuscitation (CPR), who are regularly examined with a contrast-enhanced computed tomography to…
- Trial name
- NCT05290805
- Testing
- ECMO flow rate reduction
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Patient With an Appointment for an Abdominal CT Scan and Able to Stand up for Height Measurement
Automated and Reliable Estimation of Patient Height From CT Scan Using an Artificial Intelligence Algorithm
The TAILLE study is a single-center, non-interventional (RIPH3), uncontrolled, non-randomized, open-label study.prospective study conducted at CHU Grenoble Alpes.
- Trial name
- TAILLE (NCT07864857)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Abdominal Trauma, Follow-up in Abdominal Trauma
The PseAn Study - Study Protocol
The researchers aim to study the role of contrast ultrasound in detecting post-traumatic splenic, hepatic, and renal PAs compared with the gold standard of CT with intravenous contrast at different follow-up time points, and…
- Trial name
- PseAn (NCT05627908)
- Testing
- Contrast-enhanced ultrasound
- Where
- Italy
- Volunteers
- 385 people
- Sponsor
- Niguarda Hospital
Colorectal Cancer Metastatic
Assessing How Normal Variations in CT Scanning Affects Its Interpretation
The purpose of the study is to see how measurements of tumor differences vary with slight changes in CT scan parameters. Reproducible radiomic features can be extracted for abdominal tumors, and specifically colorectal liver…
- Trial name
- NCT03038568
- Testing
- CT scan
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Peripheral Artery Disease, Diabetes Mellitus
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical…
- Conditions
- Peripheral Artery Disease, Diabetes Mellitus, Chronic Limb-Threatening Ischemia
- Trial name
- NCT03622359
- Testing
- SPECT/CT perfusion imaging, PET/CT perfusion imaging
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Coronary Artery Disease, Coronary Computed Tomography Angiography
Myocardial Perfusion Quantification With SPECT Using Multi-Pinhole Collimator Compared to Photon-Counting Coronary CTA
This prospective study aims to compare functional abnormalities detected using myocardial perfusion SPECT imaging (MPI SPECT) with the extent and severity of anatomical findings on coronary computed tomography angiography…
- Conditions
- Coronary Artery Disease, Coronary Computed Tomography Angiography, SPECT, Heart Diseases
- Trial name
- MY-FUSION (NCT06670768)
- Testing
- Stress Dynamic MPI SPECT, Stress Static MPI SPECT, Rest Dynamic MPI SPECT
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Thoracic Diseases
Evaluating a Text-Prompt AI Assistant for Chest CT Scans (AI-REPORT Study)
This study aims to find out if an artificial intelligence (AI) system can help experienced radiologists write chest CT scan reports more quickly without lowering the quality of the report.
- Trial name
- AI-REPORT (NCT07634861)
- Testing
- AI-generated report for chest CT, Standard reporting procedure (no AI assistance)
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Vertebral Fracture, Osteoporosis
Effectiveness of Implementation of Opportunistic AI-screening for Vertebral Fractures in Clinical Practice
The aim of this study is to evaluate clinical effectiveness and cost-effectiveness after implementing a medically approved and commercially available AI support system for opportunistic vertebral fracture screening in CT…
- Trial name
- vertAIdo (NCT07100756)
- Testing
- AI vertebral fracture diagnostics (Flamingo)
- Where
- Sweden
- Volunteers
- 10,500 people
- Sponsor
- University Hospital, Linkoeping
Stroke
Decentralized Imaging by REmote Computer Tomography for Cerebral Infarct Thrombolysis
The DIRECT-CT trial is designed to test the hypothesis that remote controlled CT scanning combined with real time audio-and video conference (AVC) guided assessment from an experienced hospital stroke team (tele-stroke) at…
- Trial name
- DIRECT-CT (NCT07530588)
- Testing
- Decentralized diagnostics and treatment
- Where
- 2 sites in Norway
- Volunteers
- 52 people
- Sponsor
- University Hospital of North Norway
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University