Clinical trials: Computed Tomography Angiography
Aortic Diseases
Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis
Among patients who have undergone EVAR, there is a significant risk of 20-50% endoleak. These endoleaks often require secondary interventions to reduce the risk of expansion or rupture.
- Trial name
- LEAKDYN (NCT06318780)
- Testing
- three-phase CT angiography, CEUS ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chest Pain, Acute Coronary Syndromes (ACS)
ECG-less Coronary Computed Tomography Angiography in the Management of Patients Presenting With High-troponin Chest Pain
Chest pain represents a common reason for consultation to emergency room. This symptom can be explained by a broad spectrum of conditions, from benign musculoskeletal or esophageal pain to life-threatening disease such as aortic…
- Trial name
- ECLECTIC (NCT07192965)
- Testing
- Non-ECG-gated computed tomography
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- Universitair Ziekenhuis Brussel
Coronary Artery Disease
CCTA to Optimize the Diagnostic Yield of Invasive Angiography
This study aims to reduce patient risk and costs to the healthcare system by improving the diagnostic yield of invasive coronary angiography through existing triage processes to improve risk stratification using Coronary Computed…
- Trial name
- CarDIA (NCT03554057)
- Testing
- Coronary Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- Hamilton Health Sciences Corporation
Myocardial Injury
A CCTA Guided Management Strategy Versus a Standard of Care Strategy in Type 2 NSTEMI
This study design is a prospective randomized control trial to compare outcomes between the utilization of coronary computed tomography angiography (CCTA) vs conservative treatment in type 2 NSTEMI.
- Trial name
- NCT06382402
- Testing
- CCTA scan
- Where
- United States
- Sponsor
- University of Louisville
Coronary Atherosclerosis, Diabetes Mellitus
Validation Study of Coronary CT Angiography as a Screening Tool in Asymptomatic Diabetes
The purpose of this study is to evaluate the prevalence and clinical predictors of subclinical coronary atherosclerosis and to validate the usefulness of coronary CT angiography as a screening tool in asymptomatic patients with…
- Trial name
- NCT00431977
- Testing
- coronary computed tomography angiography
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Bundang Hospital
Myocardial Ischemia
Assessment of Coronary Stenoses Using Coronary CT-angiography and Non-invasive Fractional Flow Reserve Measurement.
The purpose of this study is to determine whether a novel non-invasive method to estimate coronary blood flow (FFRct) is applicable to evaluate the functional significance of coronary stenoses in non-culprit vessels in a…
- Trial name
- NCT01739075
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- University of Aarhus
The Horseshoe Kidney
Semi-automatic Measurement of Renal Volume at CT Angiography to Plan Repair of Aortic Aneurysms in Patients With Horseshoe Kidney.
The horseshoe kidney (HK) is a congenital anomaly in which the kidneys are fused in front of the anterior aortic wall in its most common form.
- Trial name
- NCT06749782
- Testing
- TC
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS San Raffaele
Coronary Artery Disease
Computed Tomography-derived Fractional Flow Reserve vs. Angiographic Quantitative Flow Ratio in Management of Patients With Coronary Artery Disease
This is a multi-center, randomized controlled trial to compare the clinical outcomes between CT-derived fractional flow reserve (CT-FFR) guided strategy and angiography-derived quantitative flow ratio (QFR) guided strategy among…
- Trial name
- CONQUER (NCT07308496)
- Testing
- CT-FFR guided strategy, QFR guided strategy
- Volunteers
- 1,402 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Validation of Coronary Calcium Subtraction to Improve Diagnostic Accuracy of Coronary CT Angiography
Coronary calcium hampers accurate evaluation of the coronary arteries with coronary computed tomography angiography (CCTA). A novel approach to potentially overcome this limitation is coronary calcium subtraction.
- Trial name
- C-Sub320 (NCT02011061)
- Where
- 2 sites in United States, Denmark
- Volunteers
- 182 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Failure
IMAGE-HF Project I-C: Computed Tomographic Coronary Angiography for Heart Failure Patients
Background: The prevalence of heart failure (HF) is rapidly rising in industrialized and developing countries. Though invasive coronary angiography (ICA) remains the gold standard for anatomical assessment of coronary arteries…
- Trial name
- CTA-HF (NCT01283659)
- Testing
- Standard Imaging, Advanced Imaging
- Where
- 15 sites in Canada, Finland
- Volunteers
- 253 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Peripheral Arterial Diseases
Effect of Cilostazol Endothelial Progenitor Cells and Collateral Formation in Peripheral Occlusive Artery Disease (PAOD)
1. The number and function of circulating endothelial progenitor cells (EPCs) are inversely associated with coronary risk factors and atherosclerotic diseases such as PAOD. 2.
- Trial name
- NCT01952756
- Testing
- Cilostazol
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- National Cheng-Kung University Hospital
Myocardial Infarction, Percutaneous Coronary Intervention (PCI)
Investigation to Assess the Effects of Drug-COATED Balloons for Treatment of Plaques Erosions Causing Acute Coronary Syndromes
Drug eluting balloon angioplasty might be a better alternative than medical treatment or stenting in subjects with plaque erosion, which is the second most common cause of myocardial infarction.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention (PCI), Medical Treatment, Coronary Computed Tomographic Angiography
- Trial name
- DCB-PE (NCT07783880)
- Testing
- PCI with size matched DCB, GP IIbIIIa inhibitor or heparin & dual antiplatelet therapy
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- 3W-Research Collaboration Group
Intracerebral Hemorrhage
The Spot Sign for Predicting and Treating ICH Growth Study
The purpose of this study is to determine if computed tomography angiography can predict which individuals with intracerebral hemorrhage will experience significant growth in the size of the hemorrhage.
- Trial name
- STOP-IT (NCT00810888)
- Testing
- recombinant activated factor VII
- Where
- 10 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- University of Cincinnati
Stroke, Acute
Evaluation of Direct Transfer to Angiography Suite vs. Computed Tomography Suite in Endovascular Treatment: Randomized Clinical Trial (ANGIOCAT)
To evaluate the hypothesis that an ultra-fast triage with one-stop in angiography suite based on cone-beam CT compared to traditional protocol offers a better outcome in the distribution of the modified Rankin Scale scores at 90…
- Trial name
- ANGIOCAT (NCT04001738)
- Testing
- Direct Transfer to Angio Suite
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Hospital Vall d'Hebron
Coronary Artery Disease
Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
CT (computed tomography) angiography (CTA) is an examination similar to a CAT scan that uses x-rays and a contrast medium (also called dye) to visualize blood flow in arteries and veins throughout the body VISIPAQUE™ will be…
- Trial name
- NCT00348608
- Testing
- iodixanol
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- GE Healthcare
Myocardial Perfusion
Assessment of Myocardial Perfusion by Tomography and Scintigraphy in Patients With Cardiac Stress Test With Ischemia
Cardiovascular diseases are important cause of death, and of these have highlighted the Coronary Artery Disease (CAD) and its various clinical manifestations.
- Trial name
- Perfusão (NCT02810106)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Coronary Stenosis, Hemodynamics
Diagnostic Accuracy of CCTA-derived Versus AngiogRaphy-dErived QuantitativE Flow Ratio (CAREER) Study
To perform CT-QFR, invasive coronary angiography, FFR, and QFR tests on patients with moderate coronary stenosis after coronary CTA examination.
- Conditions
- Coronary Stenosis, Hemodynamics, Coronary Artery Disease, Coronary Computed Tomography Angiography
- Trial name
- CAREER (NCT04665817)
- Testing
- CT-QFR, QFR, FFR
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Fudan University
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
Coronary Artery Disease
Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease
Yearly, 180 000 patients in the Netherlands are referred to a cardiologist with symptoms suspected of coronary artery disease (CAD). To assess this, multiple diagnostic tests are available.
- Trial name
- iCORONARY (NCT04939207)
- Testing
- CT-FFR, Angiography-derived FFR, Angiography with invasive FFR-measurements
- Where
- 4 sites in Netherlands
- Volunteers
- 825 people
- Sponsor
- St. Antonius Hospital
Gastrostomy, Computed Tomography Angiography
Gastrointestinal Surgery Study Group 2001
Gastric cancer is one of the most common malignace worldwide, which caused a dramatically death rate, especially in east Asian, such as Japan , South Korea and China.
- Conditions
- Gastrostomy, Computed Tomography Angiography, Clinical Outcome
- Trial name
- GISSG2001 (NCT04636099)
- Testing
- CT angiography（CTA）
- Where
- China
- Volunteers
- 382 people
- Sponsor
- The Affiliated Hospital of Qingdao University