Clinical trials: Concentration
Neonatal Encephalopathy, Cell Damage
Inflammation and Metabolic Acidosis at Birth (AGAIN: AutophaGy AcIdosis Newborn)
Protection of brain development is a major aim in the Neonatal Intensive Care Unit. Neonatal encephalopathy (NE) occurs in 1.8 to 7.7 infants per 1000 births.
- Conditions
- Neonatal Encephalopathy, Cell Damage, Metabolic Acidosis, Inflammation
- Trial name
- AGAIN (NCT03897101)
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Attention Deficit Hyperactivity Disorder
The Association Between Executive Functions and Candidate Genes of Dopaminergic and Noradrenergic Systems in Attention Deficit Hyperactivity Disorder (ADHD)
The ultimate goal of this study is to find specific polymorphism of candidate genes (particularly of dopaminergic and noradrenergic systems) associated with intermediate phenotypes (e.g., executive functions, IQ, and other…
- Trial name
- NCT01052753
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blood Mercury Concentration
Blood Mercury Levels Following Retrograde Amalgam Surgeries
The aim of this study is to determine the blood's mercury level of patients who had amalgam root end filling surgeries. It is to be examined if the mercury concentration in blood is elevated by using amalgam retroseal.
- Trial name
- NCT01428609
- Testing
- Amalgam
- Where
- Iran
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Insulin Resistance, Type2 Diabetes Mellitus
High-fat Overfeeding, Hepatokines and Appetite Regulation
The present study will investigate the effect of high-fat overfeeding on a group of liver-secreted proteins linked to worsened blood sugar control, as well as proteins involved in appetite control.
- Conditions
- Insulin Resistance, Type2 Diabetes Mellitus, Non-Alcoholic Fatty Liver Disease, Obesity
- Trial name
- OVEREAT (NCT03369145)
- Testing
- High-fat diet
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Attention Deficit, Mobility
Cognitive and Postural Activities of Prematurely Born Children
Prematurely born children (PC) have academic difficulties related to poorer attention capabilities. Additionally, they often show excessive mobility, quoted as agitation.
- Conditions
- Attention Deficit, Mobility, Postural Activity
- Trial name
- COGNIPOST (NCT04275895)
- Testing
- Evaluation of different attention or/and postural activities
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Healthy
A Study To Observe Safety And Blood Concentrations Of PF-06649751 During And Following The Oral Administration Of Multiple Doses Of PF-06649751 In Healthy Adult Western and Japanese Volunteers
This study is designed to evaluate the safety and plasma concentrations of PF-06649751 in healthy volunteers following one or two times daily oral dosing of PF-06649751 for 14 days (Cohorts 1 - 4), 21 days (Cohort 5), or 28 days…
- Trial name
- NCT02066909
- Testing
- 0.15 mg PF-06649751, 0.5 mg PF-06649751, 1.5 mg PF-06649751
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Pfizer
Attention Deficit Hyperactivity Disorder (ADHD)
Probiotic Supplement as Treatment for Students With ADHD
Subjects will answer the following questionnaire and tests: Symptom severity and improvement will be measured using ADHA Rating scale IV (ADHD RS) Demographic Questionnaire - composed by the researchers Family Eating Habits…
- Trial name
- NCT02908802
- Testing
- Probiotic
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Healthy Volunteer
A Study Investigating the Bioavailability of a High Concentration Liquid Formulation Versus a Reference Lyophilized Formulation of Gantenerumab in Healthy Volunteers
This single-center, randomized open-label, single-dose, parallel group study will investigate the relative bioavailability of a high concentration liquid formulation (HCLF) versus the reference lyophilized formulation (LyoF) of…
- Trial name
- NCT02133937
- Testing
- gantenerumab
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Researchers Attention
Readers' Attention of Shorter Versus Longer Abstracts of Systematic Reviews
The present randomized controlled trial (RCT) was designed to investigate the perceptions of researchers on systematic review (SR) abstracts.
- Trial name
- NCT06525805
- Testing
- Long Abstract, Short Abstract
- Where
- Germany
- Volunteers
- 1,941 people, healthy volunteers welcome
- Sponsor
- University of Oldenburg
Healthy
PET Study of Repeated ASN51 in Healthy Volunteers
This is a phase 1, open-label, dose escalation, positron emission tomography (PET) study to investigate the brain occupancy of O-GlcNAcase, and the pharmacodynamics (PD) response in peripheral blood mononuclear cells (PBMCs)…
- Trial name
- NCT05725005
- Testing
- ASN51
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Asceneuron S.A.
Alcohol Use Disorder
Selective Attention in Alcohol Use Disorder
This study examines the selective attention to emotional- and alcohol- associated cues in alcohol- dependant and healthy participants.
- Trial name
- NCT03816527
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Impaired Driving
MedDrive's Responsiveness to Alcohol
This four-way, dose-response, crossover, double blind, placebo-controlled, randomised validation study investigates the responsiveness of MedDrive, a computed battery of neuropsychological tasks, to different doses of alcohol.
- Trial name
- OH-MedDrive (NCT01781273)
- Testing
- Ethanol, Cranberry juice
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sleep Disorder
Evning Exposure to Computer Screen Disrupts Sleep, Attention and Biological Rhythms
Light exposure is on the rise in recent years. In large part because of unintentional illumination from screens that emit light directly into the eyes.
- Trial name
- NCT02957383
- Testing
- Wavelength, Intensity
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
L-theanine
Theanine and Caffeine on Neurophysiology of Attention
L-theanine and caffeine are nutritional compounds that are naturally found in tea. Our recent findings using an EEG paradigm are consistent with the findings of others, indicating that intake of L-theanine and caffeine reduce the…
- Trial name
- THECNA (NCT02770105)
- Testing
- Theanine, Caffeine, Theanine-Caffeine Combination
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Obesity (BMI>30), Metabolically Healthy Obesity
Plasma Taurine in Older Women With Obesity: Impact of Metabolic Phenotype and Combined Exercise
Population aging has been accompanied by a rise in obesity and other chronic diseases, increasing cardiovascular risk particularly among women, who exhibit a higher prevalence in older age groups compared to men.
- Conditions
- Obesity (BMI>30), Metabolically Healthy Obesity, Metabolically Unhealty Obese
- Trial name
- non applicable (NCT07711899)
- Testing
- Physical Training of 16 weeks
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Malaria
Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot
Measurement of the concentration of antimalarials in the blood of the general population helps estimating the overall drug pressure and is used in efficacy studies.
- Trial name
- NCT02742285
- Testing
- Artemether + lumefantrine
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Thierry Buclin
Hepatic Impairment
A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment
The purpose of this study is to determine whether the pharmacokinetic (what the body does to the drug) parameters of telaprevir are altered in patients with moderate hepatic impairment, compared to the pharmacokinetic parameters…
- Trial name
- NCT01600976
- Testing
- telaprevir
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Janssen Infectious Diseases BVBA
Healthy Elderly Subject, Pharmacokinetic of YM150
A Study to Investigate the Plasma Concentration of YM150 After Repeated Administration to Elderly Subjects
The purpose of this study is to evaluate the safety and plasma concentration change of YM150 after repeated administration to healthy elderly male and female subjects.
- Trial name
- NCT01514825
- Testing
- YM150
- Where
- Japan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.