Clinical trials: Concentration
Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
Auditory and Visual Noise as Possible Non-pharmacological Treatment of ADHD in School Children
The goal of this study is to compare the influence of visual and auditory white noise on performance in children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06057441
- Testing
- Auditory noise stimulation, Visual noise stimulation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Region Skane
Caries
Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formulations of Fluoridated Toothpastes With and Without Post-brushing Water Rinsing.
Caries prevalence has declined significantly since the introduction of fluoridated toothpastes. Since then, different toothpaste formulations and concentrations have been introduced to the market with varying levels of efficacy.
- Trial name
- NCT02740803
- Testing
- Sodium fluoride toothpaste 1,450 ppmF, sodium monofluorophosphate toothpaste 1,450 ppmF, stannous fluoride combined with sodium fluoride toothpaste 1,450 ppmF
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Opioid-Related Disorders, Substance-Related Disorders
Isoflurane at Subanesthetic Concentrations - 6
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000254
- Testing
- 40% Nitrous oxide, 0.2% isoflurane, 0.4% isoflurane
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder
Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder
There are three purposes to this study. The first purpose is to evaluate the value of a genetic test in determining risk for autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Developmental Delay
- Trial name
- NCT01452061
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Thomas W. Frazier, Ph.D
Chronic Pain
A Study To Observe The Performance Of A Tablet Form Of PF-04531083 As Evidenced By The Concentration Of PF-04531083 In The Blood With Time Following Oral Administration To Healthy Volunteers.
A new tablet form of PF-04531083 has been manufactured. Previously the compound was administered as a solution/suspension to healthy volunteers.
- Trial name
- NCT01119235
- Testing
- PF-04531083
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
ADHD, Parenting
Helping Toddlers and Parents Together
Using stakeholder feedback (i.e., behavioral health providers \& caregivers), the goal of this study is to develop a behavioral parenting program that focuses on both parent mental health and parenting for parents of toddlers…
- Trial name
- NCT04864808
- Testing
- Behavioral Parent Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Pharmacokinetics of Darexaban and Metabolites, Healthy Subjects
To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)
The primary objective of this study is to determine the effect of ketoconazole on the blood concentrations of darexaban and its metabolites (drug degradation products).
- Trial name
- NCT01405989
- Testing
- darexaban, ketoconazole
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Rotator Cuff Tears
Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes
Randomized controlled trial comparing benefits of varying amounts of proximal humerus-derived bone marrow aspirate and bone marrow concentrate in rotator cuff repair.
- Trial name
- NCT06361797
- Testing
- Rotator cuff repair augmented with whole bone marrow, Rotator cuff repair augmented with concentrated bone marrow
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vaping, Nicotine Absorption
Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants
This is a single-center, open-label, concentration-ranging study to evaluate the nicotine PK profile and PD effects in healthy adult experienced users of closed tank/cartridge e-cigarettes using four different variants of P4M3…
- Trial name
- NCT03379740
- Testing
- E-cigarette, P4M3-1.7%, P4M3-1.7%LA
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
ADHD
Impact of A Multidimensional Health Education Program on Attention Deficit Hyperactivity Disorder (ADHD)
To measure the impact of a multidimensional health education program on patients' adherence to the healthy life style and behavioral therapy , and to correlate it with severity of ADHD symptoms
- Trial name
- ADHD (NCT06406335)
- Testing
- Health education program
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Exercise Training, Exercise Physiology
The Effects of Rule Modifications in 3v3 and 4v4 Small-Sided Games on Cardiovascular and Technical Performance in Elite Football Players
This study explores how different small-sided football games affect players' heart and technical skills. We will compare two ways of playing: "Free Play," where players act freely, and "Controlled Pass," where passing rules are…
- Trial name
- CARDIO-TECH SS (NCT07157150)
- Testing
- Free Play SSG, Controlled Pass
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hamza Kucuk
Smoking Cessation
Impact of E-cigarette Nicotine Concentration on Compensation
The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an…
- Trial name
- NCT05887947
- Testing
- Electronic Cigarette with 5% Nicotine Concentration, Electronic Cigarette with 1.8% Nicotine Concentration
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Healthy
Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)
In the present study human recombinant placental alkaline phosphatase (hRESCAP) will be investigated. Alkaline Phosphatase is naturally present in the body and reported to use lipopolysaccharde (LPS, bacterial endotoxins) and…
- Trial name
- NCT01889147
- Testing
- hRESCAP
- Where
- Netherlands
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- TNO
Attention Deficit Hyperactivity Disorder
A Bioequivalence (BE) Study in Healthy Subjects
To demonstrate the bioequivalence of 12.5 milliliters (mL) of atomoxetine oral solution (4 milligrams per milliliter [mg/mL]) compared with 2 capsules of atomoxetine (25 mg per capsule) in healthy adult male Japanese subjects.
- Trial name
- NCT01177943
- Testing
- Atomoxetine
- Where
- Japan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Infections
Assess the Plasma, Epithelial Lining, and Alveolar Macrophage Concentrations of Intravenous Meropenem-Pralubactam (Meropenem/FL058) in China Healthy Adult Participants
The goal of this clinical trial is to evaluate the Epithelial Lining Fluid concentrations and permeability of Intravenous Meropenem-Pralubactam(Meropenem/FL058) in China Healthy Adult Participants.
- Trial name
- NCT07124468
- Testing
- Meropenem-Pralubactam
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Semen Quality in Healthy Adult Men
Effects of 12-Week Combined Exercise on Semen Quality and Metabolic Health in Healthy Men
This study evaluated whether a 12-week combined aerobic and resistance exercise program could improve semen quality and metabolic health in healthy adult men. A total of 34 men aged 18-24 years participated in the study.
- Trial name
- NCT07778576
- Testing
- Combined Aerobic and Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Athletic Performance, Testosterone
Study of Testosterone and Athlete Response
Trial objectives and purpose: The primary aim is to study the effects of moderately increased testosterone concentration on aerobic performance (endurance running time to exhaustion), and secondary aims to investigate the effects…
- Conditions
- Athletic Performance, Testosterone, Women's Health: Female Athlete/Female Athlete Triad
- Trial name
- STAR (NCT03210558)
- Testing
- Testosterone cream 1% (Andro-Feme® )
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Hernia, Inguinal
The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain
The present study will be undertaken to compare the postoperative analgesic effect of 0.25% bupivacaine and 0.5% bupivacaine for unilateral ilioinguinal and Iliohypogastric nerve block after open inguinal hernia repair.
- Trial name
- NCT05687981
- Testing
- Bupivacaine, Dexamethasone
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Healthy Individuals
Study of Vitamin D Fortification of Milk and Oil
It is a two-year longitudinal effectiveness study. A comparative study with a case-control design. Study will be conducted in Pune city. A total of up to 100 families (50 families per group) will be recruited.
- Trial name
- Tata (NCT05541094)
- Where
- India
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Dr. Anuradha Khadilkar
Attention Deficit Hyperactivity Disorder
Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
ADHD is a neurodevelopmental disorder that affects about 5% of school-age children and 3.5% of adults worldwide. This condition is under-recognised in France and other European countries and, therefore, under-diagnosed.
- Trial name
- NCT01553695
- Testing
- questionary
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
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