Clinical trials: Concentration
Healthy Subjects, Plasma Concentration of Mirabegron
A Study to Evaluate Absorption, Distribution and Elimination of Mirabegron After Oral Administration to Non-elderly Healthy Chinese Subjects
The purpose of this study is to evaluate safety and absorption, distribution and elimination of mirabegron after oral administration to Chinese subjects.
- Trial name
- NCT01747564
- Testing
- YM178 (mirabegron)
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy Chinese Volunteers
Study to Assess the Safety and Plasma Concentration of YM178 OCAS Tablet (Mirabegron) in Healthy Chinese Volunteers
To evaluate the safety and plasma concentration change of YM178 after single- and repeated-administration as oral absorption controlled tablet in healthy Chinese subjects.
- Trial name
- NCT01720212
- Testing
- YM178
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma China, Inc.
Zinc Concentration in DBS
Nourishing for Knowledge: Fish Powder in School Meals in Malawi
Background: This randomized controlled trial (RCT) is a research component of a Food and Agriculture Organization of the United Nations (FAO) project in Malawi.
- Trial name
- FAO/LUANAR (NCT07085871)
- Testing
- Fish Powder
- Where
- 3 sites in Malawi
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Food and Agriculture Organization of the United Nations (FAO)
Attention Deficit Hyperactivity Disorder, Glucose Intolerance
Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity
The purpose of this study to assess the effects of chronic administration of Vyvanse (lis-dexamphetamine) on glucose metabolism in a sample of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) who also…
- Conditions
- Attention Deficit Hyperactivity Disorder, Glucose Intolerance, Obesity
- Trial name
- NCT01017263
- Testing
- Lis-dexamphetamine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Plasma Caffeine Concentration
Comparison of Plasma Caffeine Concentration After Oral Consumption of Caffeinated Beverages With Varied Bioactive Compounds in Healthy Volunteers
This is a Phase 1, double blind, randomized, controlled, cross-over trial. The primary outcome is to quantify the incremental area-under-the-concentration-curve (iAUC) for plasma caffeine after oral consumption of caffeinated…
- Trial name
- NCT04281758
- Testing
- Beverage
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Vitamin D 25-Hydroxylase Deficiency, Vitamin D Deficiency/Insufficiency
Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes
This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes.
- Trial name
- NCT07641075
- Testing
- Vitamin D supplementation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Smoking, Withdrawal Nicotine
Association Between Smoking, Brain Activity, Genes, and ADHD
The study investigated the underlying mechanisms of smoking in young adults by examining the associations between smoking, brain activity, dopamine genes, and attention deficit hyperactivity disorder (ADHD).
- Conditions
- Smoking, Withdrawal Nicotine, ADHD
- Trial name
- NCT00915798
- Testing
- Cigarette smoking, Abstinence
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cognitive Aging
Intervention Comparative Effectiveness for Adult Cognitive Training
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving…
- Trial name
- ICE-ACT (NCT03141281)
- Testing
- BrainHQ, Rise of Nations, IADL Training
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cognitive Change, Memory; Disturbance, Mild
The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy…
- Conditions
- Cognitive Change, Memory; Disturbance, Mild, Emotional Regulation, Concentration Ability Impaired
- Trial name
- Spread Bogatyr (NCT05543811)
- Testing
- Food for special dietary use
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Depressive Symptoms, Mood Disorders
Emoji-based Attention Bias Modification Training for Depressive Young Adults
Globally, the rates of young adults and college students reporting symptoms of depression have been rising over the past decade.
- Trial name
- NCT05415306
- Testing
- Attention Bias Modification, Deep-breathing training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Distraction
Measuring Attention During Immersive Virtual Reality Distraction
Brief Summary Using a repeated measures within-subject design with treatment order randomized, with healthy volunteers, this study will measure how much immersive Virtual Reality (VR) reduces performance on a simple attention…
- Trial name
- NCT06615245
- Testing
- No VR vs. immersive high tech VR, Plausible control vs immersive High Tech VR
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hunter Hoffman
Epilepsy, Cognitive Deficits
Methylphenidate Treatment of Attention Deficits in Epilepsy
Methylphenidate (MPH) has long been used to improve attention and cognitive difficulties associated with ADHD, including in children with ADHD and epilepsy (Torres et al., 2008).
- Conditions
- Epilepsy, Cognitive Deficits, Attention Deficits
- Trial name
- NCT02178995
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kimford Jay Meador
Asthma, Obesity
HealthSpark: Health Access for Children in Federally-Subsidized Child Care
HealthSpark is a community-based research network of childcare centers designed to improve the health of children in Miami-Dade County.
- Conditions
- Asthma, Obesity, ADHD
- Trial name
- NCT00339027
- Where
- United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Miami
Testosterone Deficiency
Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate
This is a randomized, open-label trial examining two doses of clomiphene citrate in men with low serum testosterone concentrations (total testosterone (TT) < 300 ng/dl).
- Trial name
- NCT05096169
- Testing
- Clomiphene Citrate 25mg, Clomiphene Citrate 50mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Essential Tremor, Parkinson's Disease (PD)
Attention and Eye Movement in Parkinson's Disease
The goal of this observational and interventional study is to understand how therapeutic deep brain stimulation (DBS) affects attention, perception and cognition in participants with Parkinson's disease (PD) and non-PD movement…
- Conditions
- Essential Tremor, Parkinson's Disease (PD), Dystonias
- Trial name
- NCT06899022
- Testing
- Normal therapeutic DBS, Reduced current DBS, Reduced frequency DBS
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Visual Perception, Attention
Effects of Acetylcholine and Attention on Visual Spatial Representations in the Brain
This study in, healthy human subjects using fMRI and MRS (magnetic resonance spectroscopy) characterizes, how attention and acetylcholine affect visual perception and the brain's representation of the visual environment.
- Conditions
- Visual Perception, Attention, Information Processing, Cholinergic System
- Trial name
- NCT05003063
- Testing
- Donepzil
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Attention Deficit Hyperactivity Disorder
Pharmacokinetic Study of DYANAVEL XR (Amphetamine) Extended-release Oral Suspension, in Children Aged 4 to 5 Years
The objective of this study was to evaluate the plasma amphetamine concentration/time profile of amphetamine extended release oral suspension in children aged 4 to 5 years with attention-deficit/hyperactivity disorder, following…
- Trial name
- NCT03610464
- Testing
- Amphetamine Extended Release Suspension [Dyanavel]
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Schizophrenia
Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia
Background: A special brain circuit is important for helping us keeping an eye open for things that are going on around us, even when we are not directly paying attention to them.
- Trial name
- NCT01399437
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pruritus
Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch
The purpose of this project is to investigate the effect of capsaicin-induced neurogenic inflammation with three different intensities on itch subsequently induced by histamine and cowhage.
- Trial name
- NCT02769910
- Testing
- Capsaicin 24 Hours, Capsaicin 1 Hour, Qutenza Demo Patch
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hjalte Holm Andersen
Aggression, Conduct Disorder
Real-time fMRI for the Treatment of Aggressive Behavior in Adolescents
The purpose of this study is to determine whether real-time fMRI feedback is effective in the treatment of aggressive behavior problems in adolescents with high callous unemotional traits when compared to treatment as usual.
- Trial name
- NCT02563145
- Testing
- Real-time fMRI feedback, Treatment as usual
- Where
- Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
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