Clinical trials: Concussion; Eye
Convergence Insufficiency, Traumatic Brain Injury
Eye Recovery Automation for Post Injury Dysfunction (iRAPID)
This study will test a portable virtual reality (VR) system with integrated eye tracking called Virtual Eye Rotation Vision Exercises (VERVE). The proposed VERVE platform will deliver vergence therapy in an automated manner.
- Conditions
- Convergence Insufficiency, Traumatic Brain Injury, Concussion, Mild
- Trial name
- iRAPID (NCT06105892)
- Testing
- Virtual Eye Rotation Vision Exercise (VERVE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New Jersey Institute of Technology
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function
An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury
The early prospective study of Traq™ (an investigational binocular ophthalmic neurodiagnostic device) will measure binocular ocular functions (bilateral foveal fixation, foveal binocularity, and fovea-tracked saccadic latency) in…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
- Trial name
- REB-001 (NCT07742878)
- Testing
- Binocular ophthalmic neurodiagnostic device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
The MESO7 study is a prospective observational research project designed to investigate the mechanisms of resilience and neurodegeneration in neurological diseases and healthy aging.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
- Trial name
- MESO7 (NCT07202494)
- Testing
- Imaging Techniques (MRI 3T & 7T, Functional, Structural, and Metabolic Imaging)
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Brain Concussion, mTBI - Mild Traumatic Brain Injury
Screening Instruments for Measuring Visual Symptoms in Victims of Concussion
Visual dysfunction after mild traumatic brain injury (mTBI) is common but often remain undiscovered during longer periods of time. No valid, reliable and easy-to-use screening instrument for uncovering visual dysfunction exists.
- Trial name
- VisCom (NCT05862571)
- Where
- Denmark
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Concussion, Convergence Insufficiency
Interventions for Convergence Insufficiency in Concussed Children
The ICONICC Study is a randomized controlled clinical trial designed to compare the proportion of successful treatment outcomes between children assigned to standard concussion care only, standard concussion care plus simple…
- Trial name
- ICONICC (NCT03908112)
- Testing
- Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT)
- Where
- 8 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Mitchell Scheiman
Concussion, Brain, Mild Traumatic Brain Injury
A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings
The purpose of this study is to develop a highly portable, ruggedized diagnostic tool for concussion, EyeBOX Lens (EBLens), that can be utilized in deployed field and far-forward settings.
- Trial name
- NCT05527041
- Testing
- EyeBOX Lens (EBLens)
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Oculogica, Inc.
Rugby Professionals, Concussion
Analysis of the Variation in Thickness of Per-papillary Retinal Optic Nerve Fibres in Professional Rugby Players
The main hypothesis is that exposure to repeated shocks is associated with a greater decrease in the thickness of optical nerve fibres.
- Trial name
- ON RUGBY (NCT03958110)
- Testing
- OCT A
- Where
- France
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Brain Concussion
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Previous research and position statements have outlined the necessity of balance and gait testing in the post-concussion evaluation of athletes.
- Trial name
- NCT02317107
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Post Concussive Syndrome, Chronic
Eye-Tracking Rapid Attention Computation
The purpose of this study is to validate and refine a diagnostic device that can detect attention and memory deficits that result from mild traumatic brain injury (mTBI).
- Trial name
- Eye-TRAC (NCT00743821)
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Brain Trauma Foundation
Convergence Insufficiency
Natural History of MTBI-related Convergence Insufficiency & Effectiveness of Vision Therapy for MTBI-related CI
The design of this project is a pilot study, a type of feasibility study conducted in preparation for subsequent RCTs that will assess the effectiveness of office-based vergence/accommodative therapy with movement (OBVAM) for…
- Trial name
- TBEye (NCT06848673)
- Testing
- Office-Based Vergence/Accommodative Therapy with Movement (OBVAM)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salus University
Brain Injuries, Traumatic
Testing Mild Traumatic Brain Injury (mTBI) in Diverse Athletic Groups
Study will test the use of a short virtual reality driven goggle test as a means of detecting mTBI in a diverse group of athletes
- Trial name
- NCT03515967
- Testing
- I-PAS Goggles
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Concussion, Mild, Concussion, Intermediate
Assessment of Oculomotor, Vestibular and Reaction Time Response Following a Concussive Event
This study is designed to evaluate the use of a collection of tests that measure the eye response, balance, oculomotor and reaction time tests to aid in the diagnosis of mTBI.
- Conditions
- Concussion, Mild, Concussion, Intermediate, Concussion, Severe
- Trial name
- NKI-RIF1 (NCT01832714)
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Neurolign
Mild Traumatic Brain Injury
The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status
The purpose of the proposed project is to determine if the VOMS is an effective screening tool to identify and track recovery of vestibular and ocular motor impairment and symptoms following mTBI, that corpsman-level medical…
- Trial name
- NCT02634944
- Testing
- Vestibular Ocular Motor Screening Tool (VOMS)
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Traumatic Brain Injury
The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury
The purpose of this study is to develop and validate eye-tracking measures that can be used to evaluate neurocognitive dysfunction among individuals with traumatic brain injury (TBI).
- Trial name
- RETINA (NCT01552577)
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Concussion, Brain, Concussion; Eye
Is Y-Balance Test Predictive of Concussion
The Y Balance Test for the lower quarter (YBT-LQ) is a movement screen used to assess an athlete's risk for injury. The YBT-LQ is a dynamic balance test where the participant stands on a single leg and with the opposite lower…
- Trial name
- NCT05344703
- Testing
- Y Balance Plus Visual Perturbations, Y balance
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Mild Traumatic Brain Injury
Integrated Eye Tracking and Neural Monitoring for Enhanced Assessment of Mild TBI: Primary Study
This study was conducted to develop and validate integrated eye tracking and EEG measures for assessment of mild traumatic brain injury.
- Trial name
- NCT03777228
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Concussion, Mild, Convergence Insufficiency
Spectacles Lens in Concussed Kids
We will be looking at 3 treatment arms in the form of different type of glasses to see if one is superior to helping kids have sustained a concussion and are symptomatic.
- Conditions
- Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
- Trial name
- SLICK (NCT03123822)
- Testing
- Glasses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
Naturally Produced Cannabinoids for Neuroprotection From Concussion
The goal of this double-blind, placebo-controlled, cross over study is to learn about the neuroprotective properties of a broad-spectrum cannabinoid formulation in normal healthy adults engaged in elite contact sport competition.
- Trial name
- NCT07715864
- Testing
- Broad spectrum cannabinoid formulation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Regina
Concussion, Eye
The Effects of Concussion on Gait and Posture in Individuals With Peripheral Vision Loss
Changes in gait and balance often occur in individuals who have suffered a concussion. In addition, a subset of concussed individuals also experience peripheral vision loss.
- Trial name
- NCT05948501
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gaylord Hospital, Inc