Clinical trials: Conditions
Chronic Periodontitis
Comparison of Alendronate With Atorvastatin in Chronic Periodontitis
The present study is designed as a single-centre, randomized, controlled clinical trial to evaluate and compare the clinical efficacy of two local drug delivery systems containing 1% ALN gel and 1.2% ATV gel in treatment of…
- Trial name
- NCT02455869
- Testing
- SRP and Atorvastatin, SRP and Alendronate
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
COPD
Inflammation in COPD and the Effect of Nicotinamide Riboside
The aim of this study is to investigate if nicotinamide riboside can reduce the airways inflammation associated with chronic obstructive pulmonary disease (COPD) in patients aged 60 or older.
- Trial name
- ICON (NCT04990869)
- Testing
- Nicotinamide Riboside
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Cancer, Quality of Life
Health and Energy Through Active Living Every Day (HEALED) After Cancer Pilot Intervention for Cancer Survivors
The proposed pilot study will test the acceptability, feasibility, and safety of a twelve-week, two-arm randomized control intervention embedded within the Cancer Prevention Study-3 (CPS-3), a prospective cohort study of cancer…
- Conditions
- Cancer, Quality of Life, Fatigue
- Trial name
- NCT03983083
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- American Cancer Society, Inc.
Obesity, Diabetes
Differential Metabolism of Dietary Fatty Acids
Differences in how diet fats are converted to energy could explain some of the reported differences in health effects among different classes of dietary fat (e.g. monounsaturated vs. saturated).
- Conditions
- Obesity, Diabetes, Hyperlipidemia
- Trial name
- NCT00059254
- Testing
- Oleic acid (OA), Palmitic Acid (PA)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sarcopenia
Effect of an EAA/Whey Composition on Protein Metabolism
Sarcopenia, a progressive loss of muscle mass, strength and function, is an inevitable natural process of aging. While it may be impossible to completely reverse the progress of sarcopenia, it is well established that intake of…
- Trial name
- NCT03502941
- Testing
- 6.3 g of EAAs mixture and whey protein isolate, 12.6 g of EAAs mixture and whey protein isolate, 12.6 g of whey protein isolate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Emergencies
Improvement of Ambulance Response Times in Karachi, Pakistan
The investigators hypothesize that spatial analysis of the location data of ambulance calls can improve prehospital care provided by Aman Foundation in Karachi, Pakistan by decreasing ambulance response times for high acuity…
- Trial name
- NCT02743169
- Testing
- Spatially-Optimized
- Where
- Pakistan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Maternal Mortality, Access to Health Care
Project to Use Community Health Workers to Reduce Maternal Deaths
The purpose of this trial is to establish if several interventions will help women in rural Tanzania access health care services during pregnancy and at the time of delivery.
- Trial name
- EWH (NCT03024905)
- Testing
- Village meeting and travel vouchers, Birth kit with misoprostol
- Where
- Tanzania
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Fibromyalgia, Central Neuropathic Pain
Nitrous Oxide as Treatment for Fibromyalgia
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
- Trial name
- NCT05357066
- Testing
- Nitrous oxide gas for inhalation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Obesity
Interventions in Nutrition Education and Skills
Healthy eating can be difficult for people who live in poor, geographically isolated regions of the United States. In particular, people who live in Appalachia often experience food insecurity (i.e., their access to adequate food…
- Trial name
- NCT02924051
- Testing
- Motivational Interviewing, Cooking skills and nutritional education
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Frances Hardin-Fanning, PhD, RN
Healthy Volunteer, Muscular Atrophy, Spinal
Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
This non-drug, single center, 24-week, longitudinal study in ambulant spinal muscular atrophy (SMA) patients and in age- and gender-matched healthy volunteers will assess the detection of disease progression by magnetic resonance…
- Trial name
- NCT02044029
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Obesity
Crave Crush Neuroimaging Study
The purpose of the research is to test whether a gymnemic acids (GA) lozenge will reduce reward region response to intake of high-sugar food and ad lib candy intake and whether the GA lozenge reduced reward region response to…
- Trial name
- NCT02949102
- Testing
- Crave Crush
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Diabetes Mellitus, Hypertension
An International Prospective, Observational, Multi-centre Study on the Duration of Pre-operative Liquid Fasting
The investigators will be performing an international prospective, observational, multi-centre, cross-sectional study to determine the actual duration of preoperative liquid fasting time in European patients.
- Conditions
- Diabetes Mellitus, Hypertension, Ischaemic Heart Disease, Comorbidities and Coexisting Conditions
- Trial name
- THIRST (NCT06527703)
- Testing
- no intervention
- Where
- Malta
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Mater Dei Hospital, Malta
Feeding Behavior, Obesity
Food Insecurity, Obesity, and Impulsive Food Choice
The objective of this study is to determine the relations among food insecurity status, obesity, and impulsive food choice patterns and to test the extent to which a mindful eating strategy reduces impulsive choice for food.
- Conditions
- Feeding Behavior, Obesity, Impulsivity
- Trial name
- FIOI (NCT02930642)
- Testing
- Mindful Eating, Nutrition DVD
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Idaho State University
Necrotic Pulp
Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars
This study will evaluate and compare the microbial efficacy of rotary and manual filing system using Neem extract, NaOCL and saline .
- Trial name
- NCT06418386
- Testing
- manual saline IA, manual neem IB, manual sodium hypochlorite IC
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Accidental Hypothermia
Active External Rewarming from Accidental Hypothermia - a Dose-response Pilot Study
The aim of this pilot study is to evaluate if there is a dose-response relationship between the use of active external rewarming devices and core temperature rewarming rate from simulated accidental hypothermia.
- Trial name
- NCT06855173
- Testing
- Active external rewarming device, Active external rewarming device 2, Active external rewarming device 3
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Overweight and Obesity
The Effect of Alginate Supplementation on Weight Management
This project will assess the effect of the alginate (in a capsules) on the weight of generally healthy volunteers over a 12 week period.
- Trial name
- NCT04589273
- Testing
- Alginate
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Pain, Abuse, Drug
Age-dependent Effects of Smoked and Oral Delta-9-THC
This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.
- Conditions
- Pain, Abuse, Drug, Intoxication; Cannabinoids
- Trial name
- SAGE (NCT05865470)
- Testing
- Cannabis, Dronabinol
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pain, Itch
Topographical Distribution of Itch and Pain Receptors
The experiment consists of three experimental sessions conducted on three consecutive days. In all experimental sessions, the participant will fill in a series of questionnaires about how you perceive itch and pain, and about…
- Trial name
- NCT07122973
- Testing
- Histamine, Cowhage, Capsaicin 8% Patch
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University