Clinical trials: Conditions
Prosthesis Related Infections
Biodistribution and Dosimetry Evaluation of [124I]FIAU
This protocol will evaluate the biodistribution and dosimetry of [124I]FIAU in both healthy volunteers and patients with prosthetic joint infections.
- Trial name
- NCT01337466
- Testing
- [124I]FIAU
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioMed Valley Discoveries, Inc
Cervical Intraepithelial Neoplasia, Cervical Cancer
Efficacy, Immunogenicity and Safety Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)
This phase III clinical study was designed to evaluate the efficacy,immunogenicity and safety of Recombinant Human Papillomavirus Vaccine (6,11,16,18,31,33,45,52,58 Type)(E.Coli) manufactured by Xiamen Innovax Biotech CO., LTD.…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Condylomata Acuminata
- Trial name
- NCT04537156
- Testing
- Nonavalent HPV vaccine, Bivalent HPV vaccine
- Where
- 2 sites in China
- Volunteers
- 9,327 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Atrial Fibrillation
Autoimmunity in the Pathogenesis of AF
This research study is being done to find out whether autoimmune mechanisms are associated with the development of atrial fibrillation.
- Trial name
- NCT03498729
- Testing
- Peripheral Blood Sample
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Shortness of Breath, Respiratory Symptoms
Work of Breathing Assessment in Triage Scale
The proposed research study will be a prospective observational study designed to validate the Canadian Triage Assessment Scale (CTAS) in regard to work of breathing in patients in the emergency department.
- Conditions
- Shortness of Breath, Respiratory Symptoms, Cough, Difficulty Breathing
- Trial name
- NCT05479929
- Testing
- Canadian Triage Assessment Scale (CTAS)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Intestinal Microbiota, Vaginal Microbiota
Characteristics of Vaginal and Intestinal Microbiota and Cervical HPV Infection
There are different microbial communities on the surface of human body (skin, hair, nails, etc.) and in the cavity connected with the outside world.
- Conditions
- Intestinal Microbiota, Vaginal Microbiota, HPV Infection
- Trial name
- NCT05003505
- Testing
- Follow up
- Where
- 8 sites in China
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Sedentary Behavior, Frail Elderly Syndrome
Effect of an Intervention on Health in Older Care Home Residents
Care home residents spent 79% of their time being sedentary. Reduced physical activity and lack of mental stimulation causes general weakness and frailty in older adults that can result in increased healthcare needs.
- Conditions
- Sedentary Behavior, Frail Elderly Syndrome, Frailty, Lifestyle, Sedentary
- Trial name
- NCT04659694
- Testing
- Wellness programme provided by Oomph! Wellness company
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bournemouth University
Pain, Anxiety
Effectiveness of the Distraction Methods During Cystoscopy
Cystoscopy is a pain procedure and patients may experience anxiety and dissatisfaction before and during the procedure. Especially male patients feel more pain than females during cystoscopy.
- Conditions
- Pain, Anxiety, Satisfaction
- Trial name
- NCT02764294
- Testing
- Music Group, Stress Ball Group, DVD Group
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Acute Agitation
Safety and Tolerability of INP105 (Olanzapine by I231 POD® Device) Nasal Spray in Healthy Volunteers - SNAP 101
The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of INP105, which is an investigational drug-device combination product comprised of the drug component OLZ administered by a…
- Trial name
- SNAP101 (NCT03624322)
- Testing
- Zyprexa IM, Zydis, INP105
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Impel Pharmaceuticals
Actinic Keratosis, Non-melanoma Skin Cancer
Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States
In this study, daylight PDT will be administered to interested patients at Dana-Farber/Brigham and Women's Cancer Center. Daylight PDT has been shown to be an effective and painless alternative to traditional PDT.
- Trial name
- DaylightPDT (NCT02867722)
- Testing
- aminolevulinic acid HCl
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Abortion, Spontaneous, Abortion in First Trimester
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic.
- Conditions
- Abortion, Spontaneous, Abortion in First Trimester, Pain Uterus, Abortion Early
- Trial name
- NCT03636451
- Testing
- 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block, 20cc 1% lidocaine with 2 units of vasopressin paracervical block
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Vision-Threatening Retinal Lesions, Urgent Referral Retinal Findings
Artificial Intelligence-Assisted Lesion-Based Urgent Referral Triage of Ultra-Widefield Retinal Images
his study evaluates the clinical utility of an artificial intelligence (AI)-assisted lesion-based urgent referral triage system for ultra-widefield (UWF) retinal images.
- Conditions
- Vision-Threatening Retinal Lesions, Urgent Referral Retinal Findings, Retinal Detachment, Pre-retinal Hemorrhage
- Trial name
- ALERT-UWF (NCT07643129)
- Testing
- AI-Assisted UWF Lesion-Based Triage System, Unassisted Interpretation
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xiamen Ophthalmology Center Affiliated to Xiamen University
Ischemic Stroke, Transient Ischemic Attack (TIA)
NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event
A natural form of vitamin E called tocotrienol (TCT), found in many common foods such as barley, decreases stroke size in animal models.
- Trial name
- NUTRITION (NCT01578629)
- Testing
- Vitamin E tocotrienol (TCT) capsules ; Low dose Aspirin
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Andrew Slivka
Telerehabilitation, Low Back Pain
Effect of Telerehabilitation Use in the Treatment of Non-specific Chronic Low Back Pain in the Brazilian Afrodescendants
The goal of this study is to measure the effect of telerehabilitation on the treatment of nonspecific chronic LBP in the adults Brazilian Black population. The main questions it aims to answer are: 1.
- Trial name
- NCT06443229
- Testing
- Graded Activity based in exercises and educational approach, Educational Approach
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Nausea and Vomiting, Bowel Functions
Menthol Chewing Gum After Laparoscopic Colorectal Surgery
This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery.
- Conditions
- Postoperative Nausea and Vomiting, Bowel Functions, Postoperative Recovery
- Trial name
- NCT07796529
- Testing
- Menthol Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Obesity
Interventionist Procedures for Adherence to Weight Loss Recommendations in Black Adolescents
To date, attempts to construct effective weight loss interventions for African American adolescents with obesity (AAAO) have largely failed.
- Trial name
- NCT01350531
- Testing
- Skills training, Contingency Management
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Infective Disorder
Clinical Trial of Comparing DA-2902 and DA-2902-R in Healthy Adult Subjects
This study is to compare pharmacokinetics and safety profiles of DA-2902 and DA-2902-R in healthy adult subjects
- Trial name
- NCT07239453
- Testing
- DA-2902, DA-2902-R
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Right Ventricular Dysfunction
Right Heart International NETwork During Exercise in Different Clinical Conditions
The aim of this registry will be to compare the pathophysiological response of the morphology and function of the right heart and pulmonary circulation assessed with resting and stress-echocardiography in patients with various…
- Trial name
- RIGHT-Net (NCT03041337)
- Testing
- stress echocardiography
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Neurocognitive Deficit
Validation of MoCA-B and MoCA-Blind for Screening Cognitive Decline
The objective of this observational study is to assess the efficacy of two neuropsychological tests (MoCA-B and MoCA-Blind) in detecting cognitive decline in older adults.
- Trial name
- NCT07846839
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Sepsis, SIRS(Systemic Inflammatory Response Syndrome)
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients
The imbalance between anti- and pro-inflammation often occurs in patients with sepsis. And continuous such imbalance could lead to immunoparalysis, which is characterized by loss of delayed type hypersensitivity, failure of…
- Trial name
- NCT01801839
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
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