Clinical trials: Conduct
Depression, Pain
Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study
The purpose of the study is to examine the connection between the dose of paroxetine and the effect of paroxetine on tramadols metabolism and thereby the effect of tramadol on the median pupil size.
- Trial name
- NCT00785603
- Testing
- Paroxetine, Tramadol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Delayed-Onset Muscle Soreness (DOMS)
The Effectiveness of Sustained Heat Treatment on Delayed-Onset Muscle Soreness (DOMS)
This post-market clinical follow-up, open-label, multicenter, randomized, parallel group clinical investigation is designed to investigate the effectiveness, safety, and tolerability of immediate and delayed ThermaCare HeatWraps…
- Trial name
- DOMS (NCT06111118)
- Testing
- ThermaCare HeatWraps
- Where
- 6 sites in Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Osteoarthritis, Knee, Depressive Symptoms
Study on Brain Structure and Function of Pain-related Emotion Disorder
By the method of multi-mode Magnetic Resonance Imaging, 5 patients with knee osteoarthritis are selected in this trial to observe the possible differences in the brain structure and function from the 5 healthy volunteers.
- Conditions
- Osteoarthritis, Knee, Depressive Symptoms, Anxiety State
- Trial name
- NCT03912610
- Testing
- Functional magnetic resonance examination
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Zhoujie
Mental Health, Psychosocial Functioning
RESETTLE-IDPs: Life-Skills Education and Psychosocial Resilience Building for Displaced Nigerians
The RESETTLE-IDPs study aims to address the urgent mental health needs of internally displaced youth and women in Nigeria, who face high rates of depression, anxiety, and post-traumatic stress due to exposure to conflict…
- Conditions
- Mental Health, Psychosocial Functioning, Implementation Science, Global Health
- Trial name
- RESETTLE-IDPs (NCT06412679)
- Testing
- Life Skills Education
- Where
- Nigeria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Physical Inactivity, Low Physical Fitness
Effect of a Female Strength & Conditioning Specialist on High School Girls' Health
The majority of today's youth do not engage in enough physical activity (PA) to maintain good health. Low PA levels are associated with poor health (e.g. diabetes, high blood pressure) and early mortality.
- Trial name
- NCT02776579
- Testing
- Girls-only resistance training
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
HIV Infections
A Behavioral Intervention to Reduce Sexual Risk Among African-American Men Who Have Sex With Men
The purpose of this project is to test the efficacy of an HIV prevention behavioral intervention to reduce sexual risk among African-American men who have sex with men (MSM).
- Trial name
- NCT00691496
- Testing
- Behavioral intervention to reduce sexual risk among African-American men who have sex with men
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Teenage Pregnancy
Girl2Girl: Harnessing Text Messaging to Reduce Teenage Pregnancy Among LGB Girls
The purpose of this study is to finalize and rigorously evaluate Girl2Girl, a novel text messaging-based teenage pregnancy prevention (TPP) program designed specifically for LGB women ages 14-18 years, nation-wide.
- Trial name
- Girl2Girl (NCT03029962)
- Testing
- Girl2Girl
- Where
- United States
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Absenteeism, Sick Leave
WB6Dim-LTSA: Can Workplace Well-Being Scores Predict Collective Absenteeism?
This prospective multicenter cohort study evaluates the predictive value of the Adaptive Load Index (ICA), a composite indicator derived from the WB6Dim well-being instrument, on long-duration sick leave (≥ 30 days) in French…
- Conditions
- Absenteeism, Sick Leave, Workplace Well-Being, Occupational Stress
- Trial name
- WB6Dim-LTSA (NCT07606261)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Clover Link
Clinical Trial
Supplementation Performance And Exercise With Euterpe Edulis for Men's Enhancement
The study aims to evaluate the effect of supplementation with Euterpe edulis on the physical and mental performance, inflammation, muscle recovery, and muscle strength of healthy men submitted to physical exercises.
- Trial name
- SPAEME (NCT06254170)
- Testing
- Euterpe Edulis juice
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Vila Velha
Depression, Smoking
Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers
This project is a treatment-matching study to test whether adding antidepressant pharmacotherapy to behavioral cessation treatment improves the depression-prone smoker's ability to quit, while not undermining cessation goals for…
- Trial name
- NCT00018174
- Testing
- Fluoxetine, Behavioral group smoking cessation treatment
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Obesity, Diet Habit
FTO Gene Variants and Diet in Obesity
Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are…
- Conditions
- Obesity, Diet Habit, Genetic Predisposition
- Trial name
- NCT04205318
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Epilepsy, Functional Neurological Disorder
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
The goal of this study is to investigate how a one-time exercise session influences different parameters of brain function in people with neurological diseases compared to healthy volunteers.
- Conditions
- Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia
- Trial name
- EXPLAIN (NCT07883720)
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Smoking Cessation
Quit and Fit: A Tobacco Cessation and Energy Balance Pilot for African Americans
The Quit \& Fit intervention will be designed as a 12-week study to promote smoking cessation, increase physical activity levels, and reduce weight gain through regular exercise and healthy nutrition for African American Women…
- Trial name
- Quit and Fit (NCT02103582)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Surgery, Adolescent Behavior
Recruitment and Behavioral Economic Strategies
To determine the impact of the application of behavioral economic strategies on recruitment of pediatric patients into a randomized clinical trial assessing the impact of technology-based interventions on postoperative pain…
- Trial name
- NCT05441579
- Testing
- Behavioral Economics (BE) recruitment strategies, Biofeedback-based virtual reality (VR-BF), Manage My Pain
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vanessa Olbrecht
Post Exposure Prophylaxis, Occupational Exposure HIV Infections Hepatitis B Hepatitis C Post-Exposure Prophylaxis
Impact of Health Education on Knowledge, Attitude and Practice of Post-exposure Prophylaxis
The goal of this study is to learn whether a short education programme helps healthcare workers know more about post-exposure prophylaxis (PEP).
- Trial name
- NCT07330427
- Testing
- Health Education
- Where
- Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aswan University
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Upper Respiratory Tract Infections, Mental Stress
A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers
This study is designed to determine if a dieatary supplement containing beta-glucan can reduce the incidence, severity and duration of upper respiratory tract infections among a group of highly trained athletes
- Trial name
- NCT05917015
- Testing
- Treatment
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- USANA Health Sciences
Breast Cancer
Peers Promoting Exercise Adoption and Maintenance Among Cancer Survivors
Exercise adoption enhances well-being and recovery from breast cancer. Researchers trained American Cancer Society volunteers to provide exercise counseling to breast cancer survivors and the survivors increased their exercise in…
- Trial name
- NCT02694640
- Testing
- Reach Plus, Reach Plus Phone, Reach Plus Message
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Ketamine Infusions for PTSD and Treatment-Resistant Depression
The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning.
- Trial name
- NCT02577250
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
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