Clinical trials: Conduct Disorders in Adolescence
Obesity, Adolescent, Dietary Sugars
A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents
The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black/African American and Latine adolescents with obesity…
- Conditions
- Obesity, Adolescent, Dietary Sugars, Taste Perception, Insulin Resistance
- Trial name
- SPARKLE (NCT07223151)
- Testing
- Unsweetened Sparkling Water Replacement, Progressively Reduced Sugar Beverage Replacement, Plain Water Replacement
- Where
- 3 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Nana Gletsu Miller
Depression, Anxiety
Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth
A 16-week double blind, placebo-controlled investigation of escitalopram in adolescents with depression and/or anxiety with a family history of Bipolar Disorder.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT02553161
- Testing
- Escitalopram, Cognitive behavioral Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Depressive Disorder, Depression - Major Depressive Disorder
A Qualitative Analysis of Youth Responses to Depression Education Delivered on Social Media
Depression is a common mental disorder among adolescents, with increased rates during the COVID-19 pandemic. Despite its high burden, few young people seek professional help due to, among other things, low mental health literacy…
- Conditions
- Depressive Disorder, Depression - Major Depressive Disorder, Depression in Adolescence
- Trial name
- NCT07100548
- Testing
- "ich bin alles" (English: "I am everything")
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Overweight Adolescents
CommitFit App to Facilitate Health Behavior Change in Clinic Adolescents
We conducted a 3-month RCT with 30 adolescents (aged 13-15 years) and their caregivers to evaluate the effectiveness of the novel mHealth app "CommitFit", which uses gamification to motivate users to log and achieve health…
- Trial name
- NCT06985251
- Testing
- gamified mHealth lifestyle app, Attention Control, gamified mHealth app with financial incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Type 1 Diabetes
Promoting Adolescent Investment In Diabetes Care
Two financial incentive strategies targeting adolescents with type 1 diabetes will be compared to usual care for motivating adolescents to engage in improved self-care to manage their diabetes.
- Trial name
- InvesT1D (NCT04516694)
- Testing
- Financial incentive (gain), Financial incentive (loss)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Attention Deficit Hyperactivity Disorder
Micronutrients for Attention-Deficit Hyperactivity Disorder in Youth (MADDY) Study
This proposed research will use randomized control trial (RCT) methodology and compare micronutrients with placebo in 135 children with ADHD.
- Trial name
- MADDY (NCT03252522)
- Testing
- Broad Spectrum Micronutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- 3 sites in United States, Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Depression
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral \& Interpersonal…
- Trial name
- P2P (NCT04290754)
- Testing
- CATCH-IT, TEAMS
- Where
- United States
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders
The investigators will recruit 30 children and adolescents (15 per group x 2 groups) aged 6 to 17 years with ASD and significant repetitive behaviors that cause problems to them and to others around them.
- Trial name
- NCT04725383
- Testing
- amitriptyline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
COVID-19
Health Information Technology for COVID-19 Testing in Schools (SCALE-UP Counts)
This project will address key testing challenges in Utah schools by building on collaborations with public school districts, private schools, charter schools and with Utah Department of Health on coronavirus disease (COVID-19)…
- Trial name
- NCT05112900
- Testing
- Text Messaging (TM), Text Messaging + Health Navigation (TM+HN)
- Where
- United States
- Volunteers
- 7,122 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Gamification and Energetic Behavior Changes
Obesity [Body mass index (BMI kg/m2 ≥ 95th percentile)] affects 1 in 5 adolescents in the United States, with 13 million suffering from severe obesity (BMI ≥ 120% > 95th percentile or ≥ 35 mg/kg2).
- Trial name
- NCT03050840
- Testing
- Way to Health
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Adolescent Psychiatry, Antisocial Personality Disorders
Impaired Decision-making in Adolescents
There is clear evidence that aggressive behavior and disruptive behavior disorders (DBD) in middle childhood are associated with an increased risk for substance abuse in adolescence.
- Conditions
- Adolescent Psychiatry, Antisocial Personality Disorders, Substance-Related Disorders
- Trial name
- NCT01253993
- Where
- Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Depressive Symptoms, Allostatic Load
Rise & Thrive: Community-Engagement Intervention for Stress and Depression in Youth.
American youth and young adults face persistent and chronic stressors, which have contributed to a mental health crisis in the United States.
- Conditions
- Depressive Symptoms, Allostatic Load, Metabolic Syndrome
- Trial name
- R&T (NCT07554326)
- Testing
- Rise Together: Community Engagement Intervention, Adulting 101: Life Skills
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Major Depressive Disorder, Depression
Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
This study will examine if brain insulin resistance is a feature of depression in humans using magnetic resonance imaging (MRI) measures sensitive to brain insulin action.
- Trial name
- NCT05571878
- Testing
- Humalog, Saline nasal spray
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health