Clinical trials: Conduction Disturbance
Cardiovascular Diseases, Cardiac Arrhythmia
Accuracy of Cardiac Arrhythmias and Conduction Disorders Diagnosis Using a Smartwatch
Implantable devices increase the detection of silent atrial fibrillation in high-risk populations, being a useful tool in the early diagnosis of these patients, allowing monitoring for a longer time.
- Conditions
- Cardiovascular Diseases, Cardiac Arrhythmia, Conduction Disturbance
- Trial name
- NCT04437914
- Testing
- Electrocardiogram diagnosis
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of Piaui
Transcatheter Aortic Valve Replacement, Conduction Disturbance
Intra-procedural ECG Changes During TAVR
The purpose of this study is to evaluate electrocardiogram (ECG) changes in 100 patients undergoing transcatheter aortic valve replacement (TAVR) to assess new-onset conduction abnormalities, such as atrioventricular nodal block…
- Trial name
- NCT05791344
- Testing
- ECG monitoring
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Cara Medical Ltd
Bradycardia
Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement
Most of the conduction abnormalities with TAVR are usually detected during the procedure or during the following days of observation.
- Trial name
- NCT03180073
- Testing
- Ziopatch Pre discharge, Ziopatch at Discharge, Ziopatch at 2 months
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Cardiac TTR Amyloidosis
Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease
Cardiac amyloidosis is a multi-organ syndrome, which usually presents as restrictive cardiomyopathy (RCM). Transthyretin (TTR) amyloidosis (or ATTR) is a subtype of amyloidosis which frequently involves heart.
- Trial name
- NCT03098901
- Testing
- Tc99m-labeled pyrophosphate scan
- Volunteers
- 100 people
- Sponsor
- Kaplan Medical Center
Transcatheter Aortic Valve Replacement
Cara CDRS (Conduction Disturbance Risk Score) 1.0
Prospective, non-randomized, multicenter data collection study. Eligible TAVR patients will be enrolled in the study. Cardiac conduction disturbances (CD) requiring permanent pacemaker implantation (PPM) or causing new-onset CD…
- Trial name
- CDRS (NCT05657912)
- Testing
- ECG monitoring
- Where
- 3 sites in Canada, Italy and 1 more
- Volunteers
- 355 people
- Sponsor
- Cara Medical Ltd
Aortic Stenosis, Transcatheter Aortic Valve Implantation
Reversibility of Cardiac Conduction Disturbances Following TAVI
The management of patients with conduction disturbances (CDs) after transcatheter aortic valve implantation (TAVI) is unclear, especially in those with de novo electrocardiographic CDs (ECG-CDs) such as left bundle branch block.
- Conditions
- Aortic Stenosis, Transcatheter Aortic Valve Implantation, Conduction Disturbances
- Trial name
- TAVI-REVERSE (NCT06481137)
- Testing
- Electrophysiological study (EP study), ePatch (extended Holter Monitoring)
- Where
- Spain
- Volunteers
- 209 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Conduction Disturbance, Trans Aortic Valve Implantation (TAVI)
Pre TAVI Membranous Septum Measurement Predicts High Grade Iatrioventricular Conduction Disorders in Patients With Specific Pacemaker Implanted After TAVI. The STIM TAVI-MS Study
Conduction disturbances are a major complication of TAVI. There is no predictor of post-TAVI conduction disorder. The study of the membranous septum on the pre-TAVI scanner and the valve implantation height are promising and…
- Trial name
- STIM TAVI MS (NCT04906837)
- Testing
- Trans aortic valve implantation
- Where
- France
- Volunteers
- 197 people
- Sponsor
- Association de Recherche en Cardiologie des Alpes
Stroke, Hemiplegia
Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations.
- Conditions
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- Trial name
- NCT07685691
- Testing
- Nerve Conduction Study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Baskent University
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Optimize RV Selective Site Pacing Clinical Trial
The purpose of the Optimize RV study is to determine the long-term effect of selective site pacing. Selective site pacing refers to which area of the right ventricle the lead is placed.
- Trial name
- NCT00422669
- Testing
- Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
- Where
- 22 sites in United States, Canada and 4 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Acute Coronary Syndrome, Heart Failure
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Syncope, Stroke
- Trial name
- FEVRIER (NCT03231449)
- Testing
- observation of current care
- Where
- 20 sites in Benin, Burkina Faso and 11 more
- Volunteers
- 5,000 people
- Sponsor
- Cardiologie et Développement
Cardiac Conduction Disturbance
Bachstim Registry: a Feasability Study of Bachmann's Area Pacing
During pacemaker implantation, the atrial lead is commonly positioned in the right atrium. However, this pacing location can be problematic because it may disrupt physiological atrial activation, leading to atrial dyssynchrony.
- Trial name
- NCT07467031
- Testing
- Bachmann's area pacing
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Transcatheter Aortic Valve Replacement
Cara CDRM (Conduction Disturbance Risk Monitor) 2.0
Prospective, multicenter, roll-in, pilot clinical trial. Study subjects will be studied during the TAVR procedure and their 12 lead ECGs collected and analyzed for New-Onset Conduction Disturbances (NOCD).
- Trial name
- Cara CDRM (NCT05465655)
- Testing
- ECG monitoring for Conduction Disturbances
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Cara Medical Ltd
Aortic Valve Stenosis, Cardiac Conduction Disturbance
Remote Cardiovascular Monitoring in Post-TAVI Patients
The goal of this randomised clinical trial is to utilise a remote monitoring algorithm to gather essential clinical data, aiming to guide the management of post-Transcatheter Aortic Valve Implantation (TAVI) patients and reduce…
- Conditions
- Aortic Valve Stenosis, Cardiac Conduction Disturbance, Digital Health, Transcatheter Aortic Valve Implantation
- Trial name
- TELE-TAVI (NCT06602609)
- Testing
- Remote Patient Monitoring Strategy, Standard Medical Therapy
- Where
- United Kingdom
- Volunteers
- 216 people
- Sponsor
- Imperial College London
Pacemaker Implantation, TAVI
STIMTAVI : Evolution of Atrioventricular Conduction Disorders After TAVI
The investigators propose to carry out an observational study of patients implanted with a pacemaker using AAI SafeR® mode after a TAVI procedure.
- Trial name
- STIMTAVI (NCT03338582)
- Volunteers
- 275 people
- Sponsor
- Association de Recherche en Cardiologie des Alpes
Chagas Disease
Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram
Chagas disease is endemic to the Americas, infecting between 16-18 million individuals. In immigrant populations in the United States from endemic areas, it is estimated up to 4.9% may be asymptomatic carriers of Trypanosoma…
- Trial name
- NCT00453700
- Testing
- Trypanosoma cruzi serology
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Multiple Sclerosis
STudy to vAlidate telemetRic ECG Systems for firsT Dose Administration of Fingolimod (START)
This study evaluated bradycardiac events during first dose observation of fingolimod in MS patients.
- Trial name
- START (NCT01585298)
- Testing
- FTY720
- Where
- 258 sites in Germany
- Volunteers
- 6,998 people
- Sponsor
- Novartis Pharmaceuticals
4-electrode Tablet-based Electrocardiogram (ECG) System, Electrical Activity of the Heart
4-electrode ECG (DigitalCardio®) vs Standard 10-electrode ECG: Evaluating Ease of Use and Recording Quality
The goal of this clinical trial is to compare the time required to record a complete Electrocardiogram (ECG) trace using the DigitalCardio (CardioSecur®) tablet device versus a standard 12-lead ECG device in eligible patients.
- Conditions
- 4-electrode Tablet-based Electrocardiogram (ECG) System, Electrical Activity of the Heart, Atrial or Ventricular Arrhythmias, Intracardiac Conduction Abnormalities
- Trial name
- FAST-ECG (NCT07732283)
- Testing
- standard 10-electrode ECG acquisition, 4-electrode DigitalCardio acquisition
- Where
- 2 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Conduction Abnormalities, Paravertebral Anesthesia
Influence of Thoracic Paravertebral Block on Atrioventricular Conduction
The aim of the study is to assess the changes in electrical activity of heart atria and in atrioventricular conduction induced by anaesthetic thoracic paravertebral blockade, depending on site on which blockade was performed.
- Trial name
- NCT06833086
- Testing
- Paravertebral block (ropivacaine) left, Paravertebral block (ropivacaine) right
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Cardiac Pacing, Right Ventricular Pacing
Optimize RV Follow-up Selective Site Pacing Clinical Trial
The purpose of the Optimize RV Follow-Up study is to determine the long-term effect of selective site pacing. Selective site pacing refers to which area of the right ventricle the lead is placed.
- Conditions
- Cardiac Pacing, Right Ventricular Pacing, Left Ventricular Ejection Fraction
- Trial name
- ORVFUP (NCT00949715)
- Testing
- Medtronic or Vitatron Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
- Where
- 12 sites in United States, Israel and 1 more
- Volunteers
- 67 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure