Clinical trials: Confusional State
Delirium
Nu-DESC DK: The Danish Version of the Nursing Delirium Screening Scale
Delirium is one of the most common complications among elderly hospitalized patients, postoperative patients and patients on intensive care units. The reported prevalence is between 11 and 80 %.
- Trial name
- Nu-DESC DK (NCT02628925)
- Testing
- Nu-DESC DK
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Delirium, Postoperative Delirium
Stanford PIPRA Validation Study in an Elderly Orthopedic Population
The purpose of this study is to determine the accuracy of an AI-based tool in the prediction of postoperative delirium (POD), in a population at moderately high risk of developing this syndrome (i.e., elderly orthopedic…
- Conditions
- Delirium, Postoperative Delirium, Cognitive Impairment
- Trial name
- PIPRA-ORTHO (NCT06567574)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Schizotypal Personality Disorder, SPD
A D1 Agonist For Working Memory
The purpose of the study is to examine the effects of the administration of a drug called DAR-0100A on attention and memory in persons with schizotypal personality disorder (SPD).
- Trial name
- NCT02507206
- Testing
- DAR 0-100A
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antonia New
Vestibular Diseases, Peripheral Neuropathies
Use of a Vibrotactile Sensory Prosthesis in Patients With Postural Imbalance and Spatial Disorientation
The investigators propose to explore the hypothesis that vibrotactile channels for indicating spatial orientation can be exploited as a sensory prosthesis.
- Conditions
- Vestibular Diseases, Peripheral Neuropathies, Proprioceptive Disorders, Hemispatial Neglect
- Trial name
- NCT00146952
- Testing
- Vibrotactile feedback
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive Changes After Major Joint Replacement
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Mild Cognitive Impairment, Delirium, Cognitive Deficit
- Trial name
- Cognigram (NCT02964221)
- Testing
- Cognitive Testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Postoperative Confusion
Cognitive Functions After TIVA With Dexmedetomidine
It is important to wake up without any problem and comfortably from the general anesthesia. The aim of this study is to investigate the effects of addition dexmedetomidine to the balanced intravenous anesthesia with propofol over…
- Trial name
- NCT02631135
- Testing
- Remifentanil, Propofol, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Delirium
Computer-assisted Cognitive Stimulation Treatment for Delirium
The objectives of our study are to determine whether people with delirium in a subacute care unit improve after one week with non-pharmacological therapies based on improving sleep schedules, mobility, and cognitive stimulation…
- Trial name
- Delitract (NCT07563244)
- Testing
- Specific computer-based cognitive stimulation intervention, Usual care intervention
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Delirium
Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2)
The IPOD-B2 Study aims to understand the pathogenesis of postoperative delirium in patients undergoing major surgery. The investigators will identify then correlate soluble biomarkers in blood and cerebral spinal fluid with…
- Trial name
- IPOD-B2 (NCT02926417)
- Testing
- High Density-Electroencephalogram
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Postoperative Delirium
Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial
The purpose of this study is to find out whether postoperative delirium can be more properly prevented by the combination of determined preventive agents in past studies.
- Trial name
- PRIDe (NCT02433041)
- Testing
- Haloperidol, Ketamine, Haloperidol + Ketamine
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Delirium, Chronic Postsurgical Pain
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
Single-celled sequencing for evaluating differences in gene expression patterns in different cell types of the dynamics of a means of this research as a starting point, to study the postoperative delirium and chronic pain at the…
- Trial name
- NCT05572307
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Type 2 Diabetes (T2DM), Geriatric Syndromes
Using Virtual Reality to Improve Medical Training
As the U.S. population ages, future physicians must be prepared to care for older adults with multiple health conditions and complex needs.
- Conditions
- Type 2 Diabetes (T2DM), Geriatric Syndromes, Disability Hearing, Disability Physical
- Trial name
- NCT07542834
- Testing
- Cinematic Virtual Reality Training, Traditional Didactic Lecture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio University
Delirium, Cognitive Impairment
Stanford ICU Delirium PIPRA Study
The purpose of this study is to determine the accuracy of the Pre-Interventional Preventive Risk Assessment (PIPRA) tool in predicting clinical cases of Intensive Care Units (ICU)-delirium, in a population at high risk of…
- Conditions
- Delirium, Cognitive Impairment, Delirium, Postoperative
- Trial name
- SIDPVS (NCT06519890)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Stanford University
Emergence Delirium, Strabismus
The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery
The present trial conducted to demonstrate the administration of sugammadex as reversal of neuromuscular blockade agent reduces the incidence of emergence agitation (EA) comparing to neostigmine
- Conditions
- Emergence Delirium, Strabismus, Pediatric ALL
- Trial name
- NCT06035757
- Testing
- Bridion 200 MG in 2 ML Injection, Pyridostigmine Bromide 5 MG/ML
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Postoperative Nausea and Vomiting, Post Operative Pain
Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children
this study will aim to evaluate the effects of dexmedetomidine, dexamethasone and Ondansetron on the prevention of postoperative nausea and vomiting in children undergoing dental rehabilitation surgery.
- Conditions
- Postoperative Nausea and Vomiting, Post Operative Pain, Emergence Delirium
- Trial name
- NCT05124067
- Testing
- Dexamethasone, Ondansetron, Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Tanta University
Delirium
Quetiapine as Prophylaxis for Delirium in CABG
low-dose quetiapine may be effective in preventing delirium in patients. The purpose of this study is to evaluate the efficacy and safety of quetiapine for delirium prophylaxis in cabg
- Trial name
- NCT05801289
- Testing
- Quetiapine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium, Falls
Prophylactic Environmental Management of Delirium
Delirium is a complex neuropsychiatric syndrome with an acute onset and fluctuating course which is presented in 15 to 20% of patients admitted to general wards.
- Trial name
- MAPDI (NCT01356810)
- Testing
- Environmental Intervention, Standard Care
- Where
- Chile
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Post Operative Delirium
The Effect of Exercise-Induced Irisin on Brain Function and Postoperative Delirium in Older Adults
The goal of this observational study is to learn how exercise-induced irisin protects the brain. It also explores irisin's effect on postoperative delirium (POD) in older adults.
- Trial name
- NCT07424170
- Testing
- Preoperative physical activity level
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Delirium
Use of Dexmedetomidine in Children Undergoing Oral Maxillofacial Surgery to Decrease Emergence Delirium
The purpose of this study is to determine whether dexmedetomidine is effective in the treatment of emergence delirium of preschool children undergoing oral maxillofacial surgery.
- Trial name
- NCT01353378
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Preoperative Anxiety (Ameliyat Öncesi Anksiyete), Emergence Delirium (Derlenme Deliryumu)
Preoperative Gamified Breathing Exercise on Anxiety and Delirium in Children.
This study aims to evaluate the effect of preoperative gamified breathing exercises on preoperative anxiety and postoperative emergence delirium in children. The intervention includes games like ball blowing and bubble blowing.
- Conditions
- Preoperative Anxiety (Ameliyat Öncesi Anksiyete), Emergence Delirium (Derlenme Deliryumu), Postoperative Complications, Pediatric Patients
- Trial name
- PED-ANX-DEL (NCT07408037)
- Testing
- Gamified Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bozok University