Clinical trials: Congestive Heart Failure(CHF)
Congestive Heart Failure
Health Literacy in Patients With Congestive Heart Failure
The primary aim of this project is to test the efficacy of an inpatient congestive heart failure (CHF) educational intervention compared with usual care among inpatients at Griffin Hospital, who are largely drawn from the…
- Trial name
- NCT00508716
- Testing
- Health Literacy-Tailored Education
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Griffin Hospital
Diabetes Mellitus, Heart Failure
Sodium-glucose Co-transporter 2 Inhibitors Effects in Failing Heart Patients
SLGT2 therapy is safety used in heart failure (HF) patients with depressed left ventricle ejection fraction (LVEF) and diabetes mellitus (DM).
- Conditions
- Diabetes Mellitus, Heart Failure, Ventricular Arrythmia
- Trial name
- NCT03977116
- Testing
- SLGT2
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Heart Failure
A Study of Accelerated Guideline-Directed Medical Therapy for Heart Failure
The aim of the study was to evaluate the efficacy and safety of a Guideline-Directed Medical Therapy (GDMT) clinic within a general cardiology practice relative to usual care.
- Trial name
- NCT07217106
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Novartis Pharmaceuticals
Delirium in Old Age, Delirium in the Intensive Care Unit
Multi-Component Delirium Prevention Bundle in Older Cardiac Intensive Care Unit Patients
The goal of this randomized controlled clinical trial is to learn whether a structured delirium prevention protocol can reduce the occurrence of delirium in older adults admitted to the cardiac intensive care unit (CICU).
- Conditions
- Delirium in Old Age, Delirium in the Intensive Care Unit, Delirium Confusional State, Delirium
- Trial name
- CICUDEL (NCT07776184)
- Testing
- Multicomponent Delirium Prevention Bundle, Control Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel Aviv Medical Center
Congestive Heart Failure
Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure
This is a Phase 2 adaptive, double-blinded, placebo-controlled, randomized, multi-center trial study to evaluate the safety and efficacy of a single dose of AB-1002, administered via antegrade intracoronary artery infusion, in…
- Trial name
- GenePHIT (NCT05598333)
- Testing
- AB-1002
- Where
- 96 sites in United States, Austria and 10 more
- Volunteers
- 150 people
- Sponsor
- AskBio Inc
Heart Failure, Chronic Heart Failure
The HEARTFELT Study
This pragmatic randomized crossover trial looks at the effect(s) of using a remote patient monitoring device (Heartfelt device) with health alerts to monitor the development of peripheral edema in patients with heart failure…
- Trial name
- HEARTFELT (NCT06222099)
- Testing
- Heartfelt Device installed, Standard care, Heartfelt-guided care
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Heartfelt Technologies
Heart Failure, Exercise Tolerance
Effects of Atrial Rate-adaptive Pacing on Exercise Capacity in Patients With Chronic Heart Failure Complicated by Chronotropic Incompetence
Chronotropic incompetence consists of an insufficient increase in heart rate during effort, and its presence is recognized as a common feature in patients with heart failure due to left ventricular systolic dysfunction…
- Trial name
- NCT01016431
- Testing
- Rate-adaptive pacemaker programming, VVI at 40 bpm
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Acute Heart Failure, Acute Renal Failure
Bladder Pressure Predicting Renal Failure in Critically Ill Patients as Compared to Hemodynamic Parameters
Studies have shown that more than 30% of the overall acute decompensated heart failure (ADHF) patients develop renal dysfunction.
- Trial name
- NCT01363505
- Testing
- BARD® Intra-abdominal Pressure monitor
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwell Health
Heart Failure
Exercise and Noninvasive Ventilation in Heart Failure Patients
Introduction: Dyspnea and fatigue determine exercise intolerance in heart failure (HF) subjects, hampering performance in activities of daily living.
- Trial name
- NCT02085122
- Testing
- noninvasive ventilation
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Pernambuco
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
Heart Failure
Interval Versus Continuous Training in LVAD Patients
Patients with a left ventricular assist device (LVAD) will be randomized to either a moderate continuous (MCT, 50-60% of VO2peak) or interval training (IT, 80-90% of VO2peak) group for 6 weeks with 3 sessions per week, lasting…
- Trial name
- TrainLVAD (NCT05121077)
- Testing
- Training
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University Hospital, Essen
Congenital Heart Disease, Smartphone Application
The Effects of a CONCOR Smartphone Application
Life expectancy of children with congenital heart disease (CHD) has increased dramatically during the past years, due to the successes of cardiac surgery.
- Conditions
- Congenital Heart Disease, Smartphone Application, Arrhythmia, Heart Failure
- Trial name
- NCT02599857
- Testing
- CONCOR smartphone application
- Where
- Netherlands
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cardiac Failure, Congestive Heart Failure
China National Heart Failure Registry
The purpose of CN-HF is to establish the national registration of hospitalized heart failure patients, evaluate and compare the clinical features and prognosis of diastolic and systolic heart failure, and find out the status of…
- Trial name
- CN-HF (NCT02079428)
- Testing
- No interventions
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Institute of Cardiovascular Diseases
Heart Failure
Polypharmacy in the Heart Failure Patient: Are All Prescribed Drug Classes Required? Statin Withdrawal Study
Heart failure (cardiomyopathy) is a chronic condition in which the heart fails to function as a pump to move blood around the body.
- Trial name
- NCT01554592
- Testing
- Withdrawal of statin therapy, Statin therapy
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- The Alfred
Acute Decompensated Heart Failure
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
The goal of this clinical trial is to compare the effectiveness of acetazolamide versus dapagliflozin as an add-on in treating acute decompensated heart failure (ADHF) in adult patients with clinical signs of volume overload…
- Trial name
- NCT06535529
- Testing
- Acetazolamide, Dapagliflozin 10mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University
Diastolic Heart Failure
Rheos® Diastolic Heart Failure Trial
The CVRx® Rheos® Diastolic Heart Failure Trial is a prospective, randomized, double blind trial with up to 60 subjects conducted at up to five centers in Europe. All subjects will be followed up to one year post implant.
- Trial name
- NCT00718939
- Testing
- Rheos Baroreflex Activation Therapy System
- Where
- 4 sites in Germany
- Volunteers
- 6 people
- Sponsor
- CVRx, Inc.
Heart Diseases, Heart Failure
Fluid Status and T1-mapping by CMR
It is unclear to what extent systemic fluid overload has an impact on T1-mapping results by cardiovascular mangetic resonance imaging.
- Conditions
- Heart Diseases, Heart Failure, Valvular Heart Disease
- Trial name
- BCM-CMR-T1 (NCT03372512)
- Testing
- Bioimpedance spectroscopy
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Heart Failure, Systolic, Morality
Impact of Cardiac Rehabilitation on Acute Heart Failure Patients With Cognitive Impairment
In heart failure patients, neuropsychological disorders have been prospectively linked to frequent hospitalizations, recurrent cardiac events, and mortality.
- Conditions
- Heart Failure, Systolic, Morality, Cognitive Impairment
- Trial name
- NCT05726565
- Testing
- multidisciplinary cardiac rehabilitation
- Where
- Taiwan
- Volunteers
- 247 people
- Sponsor
- Chang Gung Memorial Hospital
Transcatheter Aortic Valve Replacement
Prognostic Factors in NOP-LBBB After TAVI
The goal of this observational study is to find prognostic factors in patients with a new-onset persistent left bundle branch block (NOP-LBBB) after transcatheter aortic valve implantation (TAVI).
- Trial name
- ProgNOP-LBBB (NCT05654792)
- Testing
- Transcatheter aortic valve implantation
- Volunteers
- 230 people
- Sponsor
- Central Hospital, Nancy, France
Heart Failure
Hemodynamic Effects of Modulating Circulating Ketone Bodies With 1,3-butanediol
Heart Failure (HF) is a major public health issue affecting 1-2% of the Western population and the lifetime risk of HF is 20%. Despite major improvements in the management and care of patients with HF, the 1-year mortality in…
- Trial name
- KETO-BD (NCT05768100)
- Testing
- 1,3-Butanediol
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aarhus University Hospital
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