Clinical trials: Congestive Heart Failure Acute
Acute Decompensated Heart Failure, Heart Failure, Diastolic
Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure
This clinical trial aims to compare the efficacy and safety of acetazolamide versus metolazone as adjunctive treatments to standard therapy in patients with acute decompensated heart failure (ADHF).
- Conditions
- Acute Decompensated Heart Failure, Heart Failure, Diastolic, Heart Failure, Systolic
- Trial name
- NCT07199088
- Testing
- Acetazolamide, Metolazone
- Where
- Pakistan
- Volunteers
- 320 people
- Sponsor
- University of Health Sciences Lahore
Acute Heart Failure, Pulmonary Congestion
LUS in Acute Heart Failure Therapeutic Adaptation
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
- Trial name
- EPPICA (NCT04633629)
- Testing
- Lung ultrasound
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, Congestive
Heart Failure Registry
The purpose of this registry is to compile a large clinical database on the medical management of patients hospitalized with acute heart failure, using information collected from acute care hospitals across the United States.
- Trial name
- NCT00530426
- Volunteers
- 150,000 people
- Sponsor
- Scios, Inc.
Heart Failure
Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List
Heart failure affects 1 to 2% of the adult population in developed countries, representing about 55 million people worldwide. Advanced heart failure is a condition where the heart can no longer provide sufficient cardiac output…
- Trial name
- ARCADIA-HF (NCT06868797)
- Testing
- Biological sample for the measurement of suPAR levels.
- Where
- 11 sites in France
- Volunteers
- 103 people
- Sponsor
- Central Hospital, Nancy, France
Heart Failure, Resynchronization Therapy
Acute Feedback on Left ventrIcular Lead Implantation Location for Cardiac Resynchronization Therapy
Exploratory, prospective, interventional, non-randomized single-center research study to compare metrics derived from 2 or 3-D reconstructions of lead movement, bioimpedance and VCG to augmentation of left ventricular…
- Conditions
- Heart Failure, Resynchronization Therapy, Assessment of Acute CRT Response
- Trial name
- CCI impact (NCT01996397)
- Testing
- Cardiac resynchronization therapy device implantation
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Heart Failure
Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF)
Anakinra ADHF is a double-blind randomized clinical trial of anakinra, recombinant human interleukin-1 receptor blocker, or placebo in patients with acute decompensated heart failure with the aim to quench the acute inflammatory…
- Trial name
- NCT01936844
- Testing
- Anakinra (high dose), Anakinra (standard dose)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Heart Failure
Dynamic Variation of Impedance Cardiography(DYVIC) as a Diagnostic Tool of Acute Heart Failure (AHF)
the study aimed to evaluate the diagnostic performance of cardiac output (CO) change after the use of trinitrine in the diagnosis of heart failure patients with acute dyspnea.
- Trial name
- dyvic2 (NCT04484298)
- Testing
- Reference position patient is put in a 30 degree supine position during 5 minutes, nitroglucerin
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University of Monastir
Dyspnea, Congestive Heart Failure
Comparison Between Lung Ultrasound and Chest Radiography for Acute Dyspnea
For patients presenting to the Emergency Department with acute dyspnea, emergency physicians will be asked to categorize the diagnosis as acute decompensated heart failure or non-cardiogenic shortness of breath a) after the…
- Trial name
- NCT02105207
- Testing
- Lung Ultrasound, Chest Radiography
- Where
- 2 sites in Italy
- Volunteers
- 530 people
- Sponsor
- University of Turin, Italy
Heart Failure, Respiratory Insufficiency
A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
The purpose of this study is to evaluate the efficacy and safety of rivaroxaban compared with placebo in the prevention of symptomatic venous thromboembolism (VTE) events and VTE-related death post-hospital discharge in…
- Conditions
- Heart Failure, Respiratory Insufficiency, Stroke Acute, Infectious Diseases
- Trial name
- MARINER (NCT02111564)
- Testing
- Rivaroxaban, 10 mg, Rivaroxaban, 7.5 mg
- Where
- 593 sites in United States, Argentina and 35 more
- Volunteers
- 12,024 people
- Sponsor
- Janssen Research & Development, LLC
Acute Heart Failure (AHF)
Risk Factors, Etiology and Predictable Outcomes With Risk Stratification Scores in Acute Heart Failure Patients
Clinical Characteristics, Etiology, Short-Term Outcomes, and Performance of Contemporary Risk Stratification Scores in Acute Heart Failure Patients Presenting to Assiut University Heart Hospital.
- Trial name
- NCT07785531
- Testing
- Echo, Ecg, Creatinine
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Assiut University
Cardiogenic Shock, Cardiac Arrest
China Extracorporeal Life Support Registry
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective cardiac and respiratory support to patients with lungs and/or heart failure.
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress Syndrome
- Trial name
- NCT04158479
- Testing
- ECMO
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Beijing Anzhen Hospital
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Heart Failure, Acute Heart Failure
Inferior Vena CAVA and Lung UltraSound-guided Therapy in Acute Heart Failure
Between 25% and 30% of patients hospitalized for acute heart failure (AHF) are readmitted within 90 days after discharge. Mostly due to persistent congestion on discharge.
- Trial name
- CAVAL US-AHF (NCT04549701)
- Testing
- CAVAL US-guided Therapy, Standard of care
- Where
- 2 sites in Argentina
- Volunteers
- 60 people
- Sponsor
- Instituto Cardiovascular de Buenos Aires
Heartfailure
Mbarara Acute Heart Failure Registry
This is a prospective cohort to describe clinical characteristics, predictors of poor outcomes both during hospitalization and at home, functional status, and quality of life among patients aged 13 years or more, consecutively…
- Trial name
- MAHFER (NCT02721030)
- Where
- Uganda
- Volunteers
- 217 people
- Sponsor
- Mbarara University of Science and Technology
Acute Renal Failure (ARF)
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative
Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.
- Trial name
- COVD (NCT03013621)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Decompensated Heart Failure
Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure
For patients hospitalized with acute decompensated heart failure,volume removal remains the primary therapeutic objective. The current standard of care remains loop diuretics.The high likelihood of readmissions and poor outcomes…
- Trial name
- TUF (NCT01863511)
- Testing
- loop diuretic, tolvaptan, ultrafiltration
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Christ Hospital
Acute Myocardial Infarction, Heart Failure
Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment
The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort，and build a study platform for heart failure caused by AMI; To explore the 1 year…
- Trial name
- NCT03297164
- Where
- 19 sites in China
- Volunteers
- 12,043 people
- Sponsor
- Harbin Medical University
Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization
Intravenous Iron Sucrose for Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction and Iron Deficiency
Iron deficiency (ID) affects about 25% of the global population, presenting with symptoms of fatigue, weakness, and impaired cognitive function.
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization, Iron Deficiency
- Trial name
- IronSucroseHF (NCT06703411)
- Testing
- Iron Sucrose IV, Standard Medical Therapy
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Cheng-Hsin General Hospital
Shortness of Breath, Acute Respiratory Failure
Enhanced FoCUS in Patients With Shortness of Breath
Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a…
- Trial name
- eFOCUS (NCT05403619)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Nantes University Hospital
Congestive Heart Failure
A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)
To compare the effectiveness and safety of diuretics add-on strategy in chronic heart failure patients
- Trial name
- NCT02047422
- Testing
- Furosemide, metolazone, furosemid/spironolactone
- Sponsor
- Yonsei University