Clinical trials: Congestive Heart Failure Chronic
Chronic Obstructive Lung Disease (COLD), Heart Failure
Reforça't: A Community, Social, and Healthcare Program for Patients With Cardiorespiratory Conditions Upon Hospital Discharge
The goal of this randomized clinical trial is to determine whether an interdisciplinary, community-based intervention can reduce 30-day hospital readmissions and improve functional outcomes in patients aged 65 or older with…
- Trial name
- R't (NCT06897410)
- Testing
- Interdisciplinary Program for Post-Hospitalization / Hospital at home Management and Long-Term Outcomes in Older Adults with Chronic Cardiorespiratory Condition
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Corporació de Salut del Maresme i la Selva
Heart Failure, Chronic Obstructive Pulmonary Disease
Person-centred Care at Distance
The goal of the research project PROTECT is to translate the Person-Centred Care (PCC) principles into an eHealth (the use of information and communication technologies for health) context.
- Trial name
- PROTECT (NCT03183817)
- Testing
- Person-centred care at distance
- Where
- Sweden
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Chronic Obstructive Pulmonary Disease, Heart Failure
PATient Navigator to rEduce Readmissions
Staying out of the hospital is valued by patients and their caregivers. Their interests converge with those of hospitals now that high 30-day readmission rates for some conditions place hospitals at risk for financial penalties…
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Sickle Cell Disease, Myocardial Infarction
- Trial name
- PArTNER (NCT02114515)
- Testing
- Hospital usual care, Navigator intervention, Peer-led telephone support line
- Where
- United States
- Volunteers
- 1,029 people
- Sponsor
- University of Illinois at Chicago
Congestive Heart Failure
Study of Sildenafil in Advanced Heart Failure.
Despite advances in medical therapy for patients with heart failure, one-third of patients remain limited by fatigue and shortness of breath.
- Trial name
- NCT00309790
- Testing
- sildenafil
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Chronic Heart Failure
A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure
The main purpose of this study is to evaluate the effect of AZD5462 on cardiac function in participants with chronic heart failure (HF).
- Trial name
- LUMINARA (NCT06299826)
- Testing
- AZD5462
- Where
- 57 sites in United States, Bulgaria and 8 more
- Volunteers
- 375 people
- Sponsor
- AstraZeneca
Cancer, Chronic Heart Failure
Palliative Outcome Evaluation Muenster I
For patients with an advanced disease and their families an excellent and compassionate care is essential. However, in hospitals optimal end-of-life care is not yet fully realized and patient's needs are often not met.
- Conditions
- Cancer, Chronic Heart Failure, COPD Exacerbation, Palliative Care
- Trial name
- POEM I (NCT03286127)
- Testing
- specialized palliative care
- Where
- 5 sites in Germany
- Volunteers
- 347 people
- Sponsor
- University Hospital Muenster
Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive
Transforming Psychotherapy for Chronically Ill Patients
The primary objective of this research is to pilot test a brief mental heath treatment specifically tailored to meet the needs of chronically ill patients with anxiety and/or depression.
- Conditions
- Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive, Depression, Anxiety
- Trial name
- NCT00520429
- Testing
- ACCES - Adjusting to Chronic Conditions with Education and Support
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
COPD, Heart Failure, Congestive
Clinical Assessment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and/or Chronic Heart Failure (CHF)
Cigarette smoking, the major risk factor for COPD, causes not only airway and lung inflammation, but also systemic effects. These systemic effects of smoking could substantially contribute to the development of chronic diseases…
- Trial name
- NCT01114386
- Testing
- Lung function testing, echocardiography, blood sampling
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Heart Failure With Reduced Ejection Fraction, Chronic Heart Failure
Vericiguat and Exercise Hemodynamics in Patients With HFrEF
Heart failure with reduced ejection fraction (HFrEF) is associated with impaired exercise capacity and abnormal exercise hemodynamics despite contemporary guideline-directed medical therapy (GDMT).
- Trial name
- EVERHETT-HF (NCT07697365)
- Testing
- Vericiguat, Guideline-directed medical therapy (GDMT) for heart failure
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Argyrios Ntalianis
Chronic Heart Failure, Old Myocardial Infarction
Japanese OMI Treatment With Kit-positive Cells for Enhanced Regeneration
The purpose of this study is to determine the safety and effectiveness of intracoronary infusion of autologous cardiac stem cells in patients with ischemic cardiomyopathy.
- Trial name
- JOKER (NCT03351400)
- Testing
- Stem cells administered to participants
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Sakakibara Heart Institute
Chronic Heart Failure
Prediction of Outcomes in Patients With Chronic Heart Failure Based on Tissue Raman Spectroscopy
Chronic heart failure (CHF) is a syndrome complicating heart disease, the prevalence of which has reached epidemic levels. According to global statistics the most common causes of CHF are coronary heart disease (CHD): 26.5%…
- Trial name
- PROMETHEUS (NCT06393595)
- Testing
- surface enhanced Raman Spectroscopy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara State Medical University
Atrial Fibrillation, Diastolic Dysfunction
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus…
- Conditions
- Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05745337
- Testing
- As needed pharmacological rate control with beta-blocker (metoprolol tartrate, metoprolol succinate) or calcium channel blocker (diltiazem, verapamil)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
Heart Failure
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
The primary objective of the study is to evaluate the effect of empagliflozin 10 mg versus placebo on exercise ability using the 6 minute walk test in patients with chronic HF with reduced ejection fraction (LVEF ≤ 40%) Secondary…
- Trial name
- NCT03448419
- Testing
- Empagliflozin
- Where
- 109 sites in United States, Australia and 9 more
- Volunteers
- 312 people
- Sponsor
- Boehringer Ingelheim
Heart Failure
The Optimization of Medications in Chronic Heart Failure Using a Website
Heart failure (HF) is the most common hospital discharge diagnosis among older adults in the United States. Strikingly, 2 in 5 patients are readmitted within 1-year following their first HF admission.
- Trial name
- NCT04580004
- Testing
- Med Optimization Arm
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypervolemic Hyponatremia
International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
To demonstrate that after 12 weeks of open-label lixivaptan treatment, serum sodium is maintained in hyponatremic patients continuing to receive lixivaptan compared to placebo during the 4 week double blind treatment period.
- Trial name
- NCT00876876
- Testing
- Lixivaptan
- Volunteers
- 300 people
- Sponsor
- CardioKine Inc.
Coronary Heart Disease, Anemia
The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.
Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors…
- Conditions
- Coronary Heart Disease, Anemia, Bronchial Asthma, Stroke
- Trial name
- STOPRISK (NCT03945968)
- Where
- 38 sites in Russia
- Volunteers
- 16,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Heart Failure
Investigating the Role of Impella 2.5 System in Acutely Decompensated Chronic Heart Failure Patients
The primary objective of this study is to assess safety and feasibility of IMPELLA 2.5 in Acute Decompensated Heart Failure patients.
- Trial name
- RELIEF I (NCT01185691)
- Testing
- Impella 2.5
- Volunteers
- 1 people
- Sponsor
- Abiomed Inc.
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