Clinical trials: Constipation - Functional
Constipation
Mechano-physiological Approach to Anorectal Function
We hypothesize that defecatory disorders can be described in mechanical terms which would allow a mechanistic description of disorders which would in turn allow better directed biofeedback mechanisms to treat disorders of…
- Trial name
- NCT00219518
- Testing
- defecography
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Constipation, Children
Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children
Pressures measured by manometric solid-state catheters may differ according to the type of the catheter and specific anatomy and physiology of anorectum.
- Conditions
- Constipation, Children, Fecal Incontinence
- Trial name
- NCT02812823
- Testing
- High-resolution anorectal manometry
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Functional Constipation
Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
A randomized, double-blind/open-label, placebo/active-controlled, single/multiple dose, parallel, phase 1/2a trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of YH12852 in healthy subjects and…
- Trial name
- NCT02538367
- Testing
- YH12852 IR 0.05mg, YH12852 IR 0.1mg, YH12852 IR 0.3mg
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Functional Constipation
An Evaluation of the Effectiveness of a Proprietary Probiotic Blend on Functional Constipation
The primary objective for this study is to monitor the change in patient assessed symptoms of constipation in subjects taking the proprietary probiotic blend compared to those taking the placebo.
- Trial name
- NCT02418507
- Testing
- Proprietary Probiotic Blend
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Constipation, Irritable Bowel Disease
Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome
This cross-sectional, observational, controlled comparative study aims to investigate the relationship between interoception and postural control in individuals with constipation-predominant irritable bowel syndrome (IBS-C) and…
- Trial name
- NCT07870915
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Infantile Colic, Constipation - Functional
Bowel And Bladder Function in Infant Toilet Training
The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age.
- Conditions
- Infantile Colic, Constipation - Functional, Bladder Dysfunction, Toilet Training
- Trial name
- BABITT (NCT04082689)
- Testing
- Assisted Infant Toilet Training
- Where
- 6 sites in Sweden
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Constipation
Bowel Function After Minimally Invasive Hysterectomy
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort.
- Trial name
- NCT04263896
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Irritable Bowel Syndrome (IBS)
Abdominal Symptom Phenotype Study in Children
Children and adults commonly suffer from recurrent abdominal (stomach) pain. One type is called irritable bowel syndrome (IBS). IBS in adults and children is one of the most common and costly health care problems in the US.
- Trial name
- ASPPNB (NCT01204515)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Colon Disease, Functional Constipation
Non-invasive Assessment of Colonic Motility
The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures.
- Conditions
- Colon Disease, Functional Constipation, Electroenterography, Slow Transit
- Trial name
- non-CoMoti (NCT04624334)
- Testing
- Elektro-Entero-Graphy procedure, EEnG Questionnaire, Gold Standard Questionnaire
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Spinal Cord Injuries, Constipation
Pharmacokinetics of Neostigmine and Glycopyrrolate
A group of 6 able-bodied healthy volunteers will receive Neostigmine (NEO) and Glycopyrrolate (GLY) intravenously and via 2 methods of Iontophoresis (ION): one-patch and two-patch administration, with subsequent blood draws over…
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT04027972
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Constipation
Effectiveness of Electromagnetic Field Therapy in Chronic Constipation
This study was, randomise controlled study. The aim of this study was to determine the effect of transabdominal magnetic field therapy on constipation severity in patients with chronic functional constipation.
- Trial name
- NCT06578442
- Testing
- Magnetic Field Treatment, Standard Care Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Medipol University
Functional Constipation
The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8…
- Trial name
- NCT06357897
- Testing
- Local PEG4000, Commercial PEG4000
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Constipation
Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
Primary Objective: To evaluate the clinical efficacy of Naturetti (jelly sugar free) To test medication on subjects who suffer chronic functional constipation in 30 days use.
- Trial name
- NCT00931853
- Testing
- SENNA+CASSIA(Naturetti)
- Where
- Brazil
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Sanofi
Constipation
Investigating the Correlation Between Functional Constipation and Sacroiliac Joint Disorders
Constipation is a common gastrointestinal issue affecting individuals worldwide. Interferential therapy, a form of electrotherapy, has been suggested to have potential benefits in improving gastrointestinal motility and relieving…
- Trial name
- SIJ disorders (NCT07344571)
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Middle East University
Overweight, Diabetes
Functional Ingredients: Effect in Gastrointestinal System
The addition of fructans or unripe banana flour to frozen meals can change the hormonal parameters related to hunger and satiety, improve the bowel movements and increase in colonic bacteria population measured by microbiological…
- Conditions
- Overweight, Diabetes, Constipation
- Trial name
- NCT02467972
- Testing
- Ready-to-eat frozen soups added unripe banana flour, Ready-to-eat frozen soups added maltodextrin, Ready-to-eat frozen soups added inulin
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Functional Constipation
A Study to Assess the Effect of the Bio-K+ Probiotic Capsules (VL-BK-02) in Adults With Functional Constipation
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical study designed to assess the effects of IP in individuals with Functional constipation as compared to a placebo.
- Trial name
- NCT06730594
- Testing
- VL-BK-02 (25 billion CFU/Capsule)
- Where
- 6 sites in India
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Function Constipation, Anxiety
Effect of Motivational Interviewing Training on Mothers' Anxiety and Children's Constipation
Study Description (Brief Summary) Functional constipation (FC) is one of the most common gastrointestinal disorders in children.
- Trial name
- NCT07233772
- Testing
- Motivational Interview-Based Constipation Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Constipation, Gastrointestinal Discomfort
Clinical Evaluation of the Effects of EpiCor on Digestive Comfort
Previous in vitro studies suggest that EpiCor is well fermented in the colon and has prebiotic potential. The repeated long-term administration of low doses of EpiCor in the Simulator of the Human Intestinal Microbial Ecosystem…
- Trial name
- NCT03051399
- Testing
- EpiCor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProDigest
Body Image, Urinary Incontinence
Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function
The first objective to determinate the prevalence of pelvic floor dysfunction in pregnant women and in the first year postpartum.
- Conditions
- Body Image, Urinary Incontinence, Anal Incontinence, Anorectal Disorder
- Trial name
- PFD-BI (NCT03591393)
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven