Clinical trials: Consumption, Tobacco
Tobacco Use Disorder, Mental Illness
Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings
The study team will conduct a Multisite Randomized Controlled Trial to evaluate the advantages and disadvantages of two approaches for quitting smoking among people with serious mental illness (SMI).
- Conditions
- Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder
- Trial name
- MTQT (NCT05030272)
- Testing
- Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch
- Where
- 3 sites in United States
- Volunteers
- 343 people
- Sponsor
- Wake Forest University Health Sciences
Lung Cancer Screening, Tobacco Use Disorder
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA…
- Conditions
- Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
- Trial name
- NCT07576595
- Testing
- Smoking cessation multilevel Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tobacco Cessation
Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers
This pilot study is being done to adapt an effective 1 session phone coaching intervention for nonsmoking support persons to a low income population.
- Trial name
- NCT03096145
- Testing
- Telephone counseling 1 session, Mobile texting, Health incentive
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Nicotine Dependence
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high…
- Trial name
- STEP3 (NCT06053567)
- Testing
- Aerobic Exercise, Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Nicotine Dependence
A Smoking Cessation Treatment for Adult Women
The purpose of this study is to develop and pilot test a smoking cessation counseling that focuses on the perceived risks of quitting smoking (e.g., weight gain, managing cravings and negative affect, loss of enjoyment).
- Trial name
- NCT01422239
- Testing
- Tailored treatment, Standard Treatment
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Dependence, Smoking Cessation
Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study)
Varenicline and nicotine replacement therapy (NRT) are both effective smoking cessation treatments. Anecdotally smokers who are finding their quit attempt difficult have reported benefiting from adding NRT to varenicline.
- Trial name
- CONVICT (NCT01184664)
- Testing
- Nicotine Patch, Varenicline
- Where
- 2 sites in United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tobacco Use Disorder
Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD
Tobacco use is the number one preventable cause of the death in the United States, and is high among US Veterans, and those who have experienced trauma are more likely to smoke.
- Trial name
- TMS-STOP (NCT05723588)
- Testing
- active repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation, nicotine replacement therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Smoking, Smoking Behaviors
CSD210202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems
This is an open-label, randomized, 5-way crossover study designed to evaluate plasma nicotine pharmacokinetic (PK) parameters following an ad libitum use of Electronic Nicotine Delivery System (ENDS) investigational products…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04751461
- Testing
- Product A, Product B, Product C
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking Cessation, Smoking, Cigarette
Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan
Randomized, controlled, two-armed, single-blinded, superiority trial with 1:1 allocation ratio Nicotine Replacement Therapy(NRT)
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Behaviors
- Trial name
- NCT05484505
- Testing
- Nicotine patch, Nicotine gums, Brief Advice (5 A's & 5 R's), Nicotine Patch: Preloading for 4 weeks
- Where
- 2 sites in Kazakhstan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nazarbayev University
Smoking Cessation, HIV
Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS
The goal of this research study is to test how well an automated text messaging smoking treatment program helps smokers with HIV quit smoking.
- Trial name
- ProjectENDIT (NCT05746442)
- Testing
- Smartphone-delivered Automated Messaging, Nicotine patch, Brief Advice to Quit and Smoking Cessation Self Help Materials
- Where
- 3 sites in Cambodia
- Volunteers
- 800 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Tobacco Use Cessation, Tobacco Smoking
EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
This study is designed to assess whether completely electronic, HIPAA-compliant, EHR-based, closed-loop referrals for tobacco cessation from primary care clinics to a state telephone tobacco quitline service can increase the…
- Trial name
- NCT02735382
- Testing
- Tobacco quitline EHR referral, Tobacco quitline Fax referral
- Where
- United States
- Volunteers
- 14,930 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Use, Tobacco Smoking
Evaluation of a Brief Tobacco Intervention in the US Military
While the military has taken steps to reduce tobacco use over the past two decades, over a quarter of new military recruits report regular tobacco use prior to enlistment.
- Conditions
- Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe
- Trial name
- NCT03196102
- Testing
- BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention
- Where
- United States
- Volunteers
- 2,999 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use
Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
This study is proposing a four condition Electronic Tobacco Marketplace (ETM) study to determine if banning normal nicotine content (NNC) is sufficient for encouraging smokers to switch to potentially less harmful products or if…
- Trial name
- NCT05320887
- Testing
- Normal Nicotine Content Vape with all flavor e-liquids, Normal nicotine content vape with tobacco e-liquids, Low nicotine content vape with all flavor e-liquids
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tobacco Dependence
EFFECTIVENESS OF VOLITIONAL HELP SHEETS AS AN ADJUNCT TO TREATMENT TO PROMOTE BEHAVIOR CHANGE: A PILOT STUDY ON SMOKING
Smoking is a major public health concern associated with substantial morbidity and premature mortality. Planning may help people who wish to change their smoking behavior by translating their intentions into action.
- Trial name
- VHS_T (NCT07910214)
- Testing
- Smoking-Specific Volitional Help Sheet
- Where
- France
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Clinique de la Mitterie
Tobacco Use
The Impact of E-liquid Nicotine Content on Reinforcement in Current Smokers
Participants will complete a phone screen and then one laboratory session. After completing in-person screening assessments, eligible participants will complete additional questionnaires.
- Trial name
- NCT03186911
- Testing
- E-liquid sampling and preference assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Cessation
Enhancing Quitline Services for African American Smokers
This study proposes to test the value of a culturally specific program for African American smokers to quit smoking.
- Trial name
- NCT03064971
- Testing
- Standard Care, smoking cessation DVD, PTF DVD
- Where
- United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Cigarette Smoking, Addiction
Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population.
- Conditions
- Cigarette Smoking, Addiction, E Cig Use
- Trial name
- NCT04063267
- Testing
- E cigarettes, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nicotine Use, Tobacco Use
Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers
Given the challenges to delivering tobacco cessation treatment in oncology care and the unique challenges faced by individuals attempting to quit tobacco after a cancer diagnosis, scalable cessation programs that are tailored to…
- Trial name
- NCT06851936
- Testing
- Nicotine cessation program
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Florida
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