Clinical trials: Contact Allergy
Cutaneous Patch, Dermatitis
Evaluation of Irritancy/Allergic Sensitivity to Natural Personal-care Products by Patch Tests
The purpose of the study is to determine if any of Mother's Choice' all-natural personal-care products cause either irritation or allergic reaction when applied to both normal or sensitive skin.
- Conditions
- Cutaneous Patch, Dermatitis, Allergy, Cosmetic Allergy
- Trial name
- NCT01816542
- Testing
- patch tests on healthy skin
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother's Choice Ltd
Allergic Contact Dermatitis
Efficacy of Baricitinib In Treatment of Delayed-Type Hypersensitivity Versus Irritant Skin Reactions in Healthy Adult Male Subjects
The treatment of allergic contact dermatitis (ACD) can be unsatisfactory, and that other skin diseases such as atopic dermatitis have an increased likelihood of ACD, improved systemic treatments are needed.
- Trial name
- NCT03945760
- Testing
- Baricitinib
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Wright State Physicians
Atopic Dermatitis (AD), Psoriasis
A Clinical Evaluation of Marula-Derived Ceramide Cream on Skin Barrier Function Enhancement
Previously, the investigators have demonstrated in vitro the excellent efficacy of marula oil-derived ceramide NPs in enhancing skin barrier function.
- Conditions
- Atopic Dermatitis (AD), Psoriasis, Acne Vulgaris, Contact Dermatitis
- Trial name
- NCT07066150
- Testing
- Apply a cream containing 0.05% marula oil-derived ceramide NPs
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shanghai Chicmax Cosmetic Co., Ltd.
Allergic Contact Dermatitis
Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool
Linalool is currently one of the most used fragrance substances in cosmetic and household products. Previous studies report a high prevalence (5.9-11.7%) of contact allergy to hydroperoxides of linalool (Lin-OOH)1.0% in pet.
- Trial name
- NCT05858723
- Testing
- ROAT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Allergy Research Center, Denmark
Allergic Contact Dermatitis
Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis
The purpose of this study is to evaluate the safety and efficacy of EB01 Cream (0.2%, 1.0%, 2.0%) applied twice per day (BID) for the treatment of moderate to severe chronic allergic contact dermatitis (ACD).
- Trial name
- NCT03680131
- Testing
- EB01 Cream 0.2%, EB01 Cream 1.0%, EB01 Cream 2.0%
- Where
- 15 sites in United States, Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Edesa Biotech Inc.
Keloid, Tattoo
Tattooing and Piercing Among Medical Students
The aim of this study is to evaluate medical students' attitudes towards tattoos and piercings and to measure their awareness of associated dermatological risks.
- Conditions
- Keloid, Tattoo, Infection, Scar
- Trial name
- NCT07673484
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Biruni University
Allergic Contact Dermatitis Due to Cosmetics
Low Dose Exposure to Oxidized R-limonene - A Repeated Open Application Test (ROAT) Study
This study evaluates the clinical and molecular effect of daily exposure to low doses of the fragrance contact allergen oxidized R-limonene.
- Trial name
- NCT03313232
- Testing
- ROAT with oxidized R-limonene at 1%, 0.3% and 0.1%, ROAT with oxidized R-limonene at 1%
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Atopic Dermatitis, Psoriasis
Molecular and Cellular Characterization of Spongiotic Dermatitis
Spongiotic dermatitis is the histopathologic diagnosis commonly issued by dermatopathologists that encompasses atopic dermatitis, contact dermatitis, and other forms of eczematous dermatitis.
- Conditions
- Atopic Dermatitis, Psoriasis, Contact Dermatitis
- Trial name
- Spongiotic (NCT00371163)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Dermatitis, Allergic Contact
Cutaneous and Systemic Reactions to Metal Implants
The purpose of this study is to evaluate if metal patch testing in metal allergic patients is useful for predicting the development of allergic skin disease or systemic symptoms in patients who recieve a metal orthopedic implant.
- Trial name
- NCT02483728
- Testing
- Patch Test
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
A Pilot Study on Use of Liquid Crystal Contact Thermography to Detect Early Breast Cancer
The study was a multicentre, observational, cross-sectional, open and monitored trial involving 274 females who were subject to an examination using liquid crystal contact thermography device as a complementary tool to standard…
- Trial name
- NCT03858738
- Testing
- Thermographic breast examination performed by Braster device
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Braster S.A.
Myopia
Visual Outcomes And Contrast Sensitivity After Myopic Wavefront-Optimized Lasik With Nexisvision Shield Or Bandage Contact Lens
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK with a Nexisvision Shield or bandage contact lens placed postoperatively.
- Trial name
- NCT01706237
- Testing
- Nexisvision shield
- Volunteers
- healthy volunteers welcome
- Sponsor
- Durrie Vision
Medical Adhesive Allergy, Dermatologic Conditions
Foam Tape Allergy a Sticky Situation
Foam tape is commonly used in the emergency department as a dressing over chest tubes owing to its occlusive and compressible properties.
- Conditions
- Medical Adhesive Allergy, Dermatologic Conditions, Dermatologic Lesions
- Trial name
- NCT06059417
- Testing
- 2x2 inch piece of 3M microfoam adhesive
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Sensitivity, Contact
Sensitization Study of ATx201 in Healthy Volunteers
This is a Phase I, single-site study to evaluate the sensitization potential of topically applied ATx201 GEL, 2% and 4%, along with a placebo control, in healthy human subjects.
- Trial name
- NCT03375957
- Testing
- ATx201
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- UNION therapeutics
Contact Allergic Dermatitis, Adverse Skin Reaction
Aquacel Hypersensitivity Dressing in TJAs
The aim of this multi-surgeon, single institution study is to prospectively evaluate the incidence of allergic contact dermatitis (ACD) following application of AQUACEL Ag, a silver-containing hydrofiber dressing, in total hip…
- Trial name
- NCT06011629
- Testing
- Aquacel dressing
- Where
- United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Healthy
Evaluation of Tetrix Cream in the Healing of Injured Skin in Subjects With Contact Dermatitis
To determine if Tetrix Cream,, when applied to the skin lesions on patients with contact dermatitis, slows or interferes with the healing of the lesions.
- Trial name
- NCT00643214
- Testing
- Tetrix
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Photoallergy
To Test for Photo Allergy Reaction of Sunscreens
The primary objective of this tudy was to evaluate the potential of photoallergy of of sun care products Sun Protection Factor (SPF) 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 application compared to that of a negative…
- Trial name
- NCT02872220
- Testing
- SPF 50 Y65 110 (BAY987519), SPF 50 Y51 002 (BAY987519), SPF 15 V27 104 (BAY987519)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer
Allergic Contact Dermatitis
Allergy Skin Patch Artificial Intelligence (AI)
The purpose of this research is to assess human and artificial intelligence performance in grading contact dermatitis reactions in healthy volunteers.
- Trial name
- NCT05339750
- Testing
- AI-based smartphone application, Allergen patch
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Allergic Contact Dermatitis
Immune Reactions in Contact Dermatitis Affected Skin
This study hopes to improve the investigators understanding of how the immune system acts in allergic contact dermatitis. In order to reach this goal, normal volunteers, who are suspected of having allergic contact dermatitis…
- Trial name
- NCT01546298
- Testing
- Patch tests
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Phototoxicity.
This is a clinical study for health care product safety assessment. The research is going to conducted with 55 subjects, aged 18 to 70 years. The product is applied on the right and/or left participant back.
- Trial name
- NCT04332445
- Testing
- Hyaluronic Acid Gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Cornea, Sense Loss; Cornea
Investigation in Corneal Sensation and Contact Lens Wear
The aim is to find out more about how corneal sensory fibres react to different types of stimuli (liquid / tactile / nylon thread) and how this can be consciously perceived by the individual.
- Trial name
- NCT04804592
- Testing
- Tactile Esthesiometer Prototype, Liquid Jet Esthesiometer Prototype, Cochet Bonnet esthesiometer
- Where
- Switzerland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch