Clinical trials: Contact Lens Discomfort
Dry Eye, Contact Lens Discomfort
Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003%
Dry Eye Disease is a multifaceted condition which has symptoms such as eye dryness, burning, and stinging sensation in the eyes. As well as clinical diagnosis such as a decreased ability to create tear film.
- Conditions
- Dry Eye, Contact Lens Discomfort, Eye Drops
- Trial name
- NCT07848373
- Testing
- acoltremon 0.003%
- Volunteers
- 50 people
- Sponsor
- Eye Research Associates, LLC
Contact Lens Discomfort
Neurolens and Contact Lens Discomfort
The objective of this study is to determine how neurolens® influences contact lens discomfort in uncomfortable myopic soft contact lenses wearers.
- Trial name
- NCT05801991
- Testing
- Neurolens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Dry Eye, Contact Lens Acute Red Eye
Performance and Tolerability of the Medical Device LACRIACT
The goal of this study is testing LACRIACT® eye drops, a medical device, to see how well it works and if people can use it safely.
- Conditions
- Dry Eye, Contact Lens Acute Red Eye, Photophobia, Discomfort
- Trial name
- NCT06159569
- Testing
- LACRIACT
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Laboratórios Baldacci S.A
Contact Lens, Questionnaire
Chinese Translation and Validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8)
This is a cross-cultural adaptation, evaluation and validation study of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among soft contact lens wearers in China.
- Conditions
- Contact Lens, Questionnaire, Contact Lens Discomfort
- Trial name
- CLDEQ-8 (NCT05416528)
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Contact Lens Discomfort
Safety, Tolerability and Pharmacodynamics of AZR-MD-001 in Contact Lens Discomfort (CLD)
A two stage, multi-center, vehicle-controlled study to determine common symptoms in patients with Contact Lens Discomfort (CLD) in Stage 1 and to evaluate the safety, tolerability, and pharmacodynamics of AZR-MD-001 in Stage 2.
- Trial name
- NCT05548491
- Testing
- AZR-MD-001 ointment/semi-solid drug
- Where
- 2 sites in Australia
- Volunteers
- 67 people
- Sponsor
- Azura Ophthalmics
Contact Lens Discomfort, Contact Lens-induced Corneal Disorder
Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel
This study compares contact lens comfortable wear duration, and signs and symptoms of contact lens discomfort, test versus control.
- Conditions
- Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining
- Trial name
- NCT03994406
- Testing
- CLM2 topical gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Glia, LLC
Meibomian Gland Dysfunction (MGD), Contact Lens Discomfort (CLD)
An Evaluation of AZR-MD-001 as Treatment for Meibomian Gland Dysfunction (MGD) or Contact Lens Discomfort (CLD)
SOVS2019-070 is a single-center study of AZR-MD-001 ointment and AZR-MD-001 vehicle in patients with Meibomian Gland Dysfunction (MGD) or Contact Lens Discomfort (CLD).
- Trial name
- NCT03972501
- Testing
- AZR-MD-001 Vehicle, AZR-MD-001 Active Dose
- Where
- Australia
- Volunteers
- 26 people
- Sponsor
- Azura Ophthalmics
Contact Lens Discomfort, Dry Eye
Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Clinicians commonly use artificial tears off label for treating contact lens (CL) discomfort and the dry eye associated with CLs because new artificial tear formulations have the potential to outperform the available CL rewetting…
- Trial name
- NCT03682809
- Testing
- Systane Complete
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Contact Lens Discomfort
The Effect of Eyelid Margin Debridement on Contact Lens Discomfort
In this study, clinical variables related to eyelids that potentially have an effect on contact lens discomfort will be investigated such as eyelid signs and secretions, eyelid sensitivity, eyelid microbiome, Demodex infestation…
- Trial name
- NCT03311204
- Testing
- BlephEx, Lid Hygenix
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Ocular Discomfort, Ocular Inflammation
Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease
Every night during sleep, there is an accumulation of white blood cells in the closed eye. The closed eye white blood cells are predominantly neutrophils, but there is a small population (3%) of T cells.
- Conditions
- Ocular Discomfort, Ocular Inflammation, Dry Eye, Contact Lens Complication
- Trial name
- NCT03408015
- Testing
- Lifitegrast
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens, Contact Lens Discomfort
Lifitegrast 5% Ophthalmic Solution and Contact Lens Dryness
The most common reason for contact lens discontinuation is contact lens discomfort. The investigators believe that inflammation plays a role in contact lens discomfort and the use of lifitegrast 5% ophthalmic solution may reduce…
- Conditions
- Contact Lens, Contact Lens Discomfort, Contact Lens Dryness
- Trial name
- NCT03686878
- Testing
- Lifitegrast
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- EV Clinical Trials
Contact Lens Discomfort, Meibomian Gland Dysfunction
Meibomian Gland Dysfunction Management
The purpose of this study is to compare electronic debridement of the eyelid margin (BlephEx) to manual debridement of the eyelid margin as treatment options for patients intolerant to contact lens wear consequent to Meibomian…
- Trial name
- NCT03652337
- Testing
- BlephEx, Manual debridement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of the Incarnate Word
Contact Lens Discomfort, Dry Eye Disease
Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers
The purpose of this prospective study is to evaluate the benefits of using the Bruder Moist Heat Compress in contact lens wearers who report reduced comfortable wear time.
- Conditions
- Contact Lens Discomfort, Dry Eye Disease, Meibomian Gland Dysfunction
- Trial name
- NCT02848222
- Testing
- Bruder Moist Heat Compress, Washcloth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham