Clinical trials: Contact Lenses
Myopia
Novel Multifocal Soft Contact Lens Study
A single site, open label protocol will be used to evaluate the safety and quality of vision of a novel soft contact lens. Habitual contact lens wearers will be asked to come to the study site for one visit.
- Trial name
- NCT06172881
- Testing
- Investigational Contact Lens
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
An Evaluation Of The Fitting Success Rate Of Senofilcon A Soft Contact Lenses In Three Designs.
This study will compare the on-eye fitting characteristics of three types of contact lenses. Each lens pair will be worn for 30 to 45 minutes before assessment and the results will be compared to mathematically calculated fitting…
- Trial name
- NCT03384628
- Testing
- First pair Senofilcon A contact lens, Second pair Senofilcon A contact lens, Third pair Senofilcon A contact lens
- Where
- 2 sites in United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Graeme Young
Contact Lens Related Dry Eye
The Impact of Hypo-osmolar Drops on Contact Lens Comfort
This pilot study will investigate the impact of sterile saline drops that are formulated at hypo-osmolar levels on CL comfort in comparison to an iso-osmolar drop, in a group of symptomatic CL wearers.
- Trial name
- SAFFRON (NCT03050125)
- Testing
- Hypo-osmolar drop 1, Hypo-osmolar drop 2, Iso-osmolar drop
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre for Contact Lens Research
Corneal Abrasion, Eye Trauma
Bandage Contact Lenses for Corneal Abrasions
Two percent of all patients presenting to the Emergency Departments have complaints involving the eye. Corneal abrasions are a common diagnosis with patients with eye pain and often cause significant discomfort.
- Trial name
- NCT03206723
- Testing
- Bandage contact lens, Eyedrop, Hydrocodone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Visual Performance
Evaluation of Two Marketed Multifocal Contact Lenses
This is a single-masked, randomized, cross-over, dispensing, 6- visit pilot study. The purpose of this clinical study is to evaluate the performance of two marketed multifocal lenses.
- Trial name
- NCT03322423
- Testing
- Multifocal Contact Lens 1, Multifocal Contact Lens 2, Spherical Contact Lens 2
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Epithelial Disruption, Corneal Staining
Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations
The purpose of this study is to quantify the amount of corneal staining observed with various marketed contact lens/multipurpose solution combinations.
- Trial name
- NCT00381446
- Testing
- Marketed contact lens care products
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrasko, Gary, OD, LLC
Visual Acuity
2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population
The primary objective of this study is to evaluate the clinical performance of two marketed silicone hydrogel contact lenses in an Indian population in the following areas: physiological characteristics, comfort characteristics…
- Trial name
- NCT02394808
- Testing
- senofilcon A, lotrafilcon B
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Astigmatism
Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses
This is a multicenter study to evaluate the clinical performance of the SynergEyes A2 lens in patients with refractive errors with or without astigmatism.
- Trial name
- NCT01058629
- Testing
- SynergEyes A2 Hybrid Contact Lens
- Where
- 10 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- SynergEyes, Inc.
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Color Vision Defects, Color Blindness
Performance of Red Tinted Contact Lenses on Colour Defects
This study aimed to relate and compare the performance of 4 types of red-tinted contact lenses (CL) with the Total Error Score (TES) from the Farnsworth-Munsell 100 Hue test on colour deficient subjects.
- Trial name
- CL (NCT05643222)
- Testing
- red tint contact lenses
- Where
- Malaysia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Dry Eye, Dry Eye, Evaporative
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers
Miebo (Perfluorohexyloctane) is a novel, non-aqueous, single entity, preservative free, ophthalmic drop. This drop was recently approved by the Food and Drug Administration (FDA) for the treatment of Meibomian Gland Disease…
- Conditions
- Dry Eye, Dry Eye, Evaporative, Dry Eye Disease, Evaporative Dry Eye
- Trial name
- NCT06176651
- Testing
- Miebo
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Myopia
Product Performance of a Daily Disposable Contact Lens
The objective of this one week, single group, bilateral, open-label study is to evaluate the product performance of the Bausch \& Lomb daily disposable cosmetic tint contact lens (Test) when worn on a daily disposable basis by…
- Trial name
- NCT01230554
- Testing
- Daily disposable cosmetic tint lens
- Where
- Singapore
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Presbyopia, Refractive Errors
Apioc Presbyopic Contact Lens
In this study, you will wear an invesetigational contact lens, Apioc-P or Apioc-PT, the way you wear your current contact lenses for approximately one month (no more than 35 days).
- Trial name
- NCT04437732
- Testing
- Apioc-P and Apioc-PT Contact Lens Design
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Keratoconus
Validation of Innovative Scheimpflug Topography Derived RGP Contact Lens Designs In Optometry Network
The goal of this Prospective, single-site, cohort study is to validate rigid gas permeable corneal contact lens (RGP) designs for keratoconus derived from combining the data from corneal topography scans and contact lenses…
- Trial name
- VISION (NCT06312163)
- Testing
- The contact lens to be investigated in this study (Scheimpflug topography derived corneal RGP contact lens design). A CE (UKCA) marked class 2 medical devices.
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Contact Lens Wear
Compliance and Contamination in Soft Contact Lens Wearers
The purpose of this study is to assess the lens and lens case microbial colonization associated with marketed care solutions used by experienced soft lens wearers.
- Trial name
- NCT01069237
- Testing
- OPTI-FREE RepleniSH, Clear Care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens, Questionnaire
Chinese Translation and Validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8)
This is a cross-cultural adaptation, evaluation and validation study of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among soft contact lens wearers in China.
- Conditions
- Contact Lens, Questionnaire, Contact Lens Discomfort
- Trial name
- CLDEQ-8 (NCT05416528)
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
A Study to Evaluate a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses.
- Trial name
- NCT01309893
- Testing
- Investigational Lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Myopia Control Using Optimized Optical Defocus RCTs
The aims of the study is to evaluate whether the DISC3.5 Plus contact lens will slow myopia progression and axial length growth in myopic children as compared with single vision soft contact lenses.
- Trial name
- NCT03681366
- Testing
- DISC3.5 plus
- Where
- China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dry Eye and Contact Lens Wear
Evaluation of Corneal Epithelial Thickness Mapping
Optovue has developed a new feature for mapping corneal epithelial thickness. The purpose of the study is to evaluate the accuracy and repeatability of the epithelial thickness measurement.
- Trial name
- NCT01712022
- Where
- 3 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Optovue