Clinical trials: Contamination
Staphylococcus Aureus Bacterial Contamination
Investigation of Antibacterial Effect of Levobupivacaine on Staphylococcus Aureus
This experimental in vitro study aimed to investigate the antibacterial effect of levobupivacaine on Staphylococcus aureus in a patient-controlled analgesia (PCA) model at concentrations commonly used for postoperative pain…
- Trial name
- NCT07285759
- Testing
- Levobupivacaine, Fentanyl, Saline
- Volunteers
- 40 people
- Sponsor
- Dokuz Eylul University
Haemostatic, Bacterial De-contamination
Pilot Study,Diode Laser 808 nm Supported Direct Pulp Capping in Permanent Teeth
The purpose of this study was to compare the conventional and diode 808 nm laser-assisted techniques in direct pulp capping in permanent teeth .The present study was based on a series of ten clinical studies with pulp exposure…
- Conditions
- Haemostatic, Bacterial De-contamination, Bio-stimulation, Reparative Dentine Formation
- Trial name
- Laser in DPC (NCT01907919)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yazdanfar, Iraj, M.D.
Bacterial Infections, Surgical Site Infection
RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?
Purpose: The purpose of this study is to evaluate if type of nail polish (gel polish or regular polish) has an effect on the number of bacterial colonies on finger nails after surgical scrubbing.
- Conditions
- Bacterial Infections, Surgical Site Infection, Contaminated Medical or Biological Substances
- Trial name
- RBG (NCT05210920)
- Testing
- Nail polish application
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronavirus, Covid19
Impact of Aerosol Box Use on Healthcare Provider Contamination
Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses.
- Conditions
- Coronavirus, Covid19, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04880668
- Testing
- Aerosol Box (Splashguard)
- Where
- 4 sites in United States, Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Contaminated Medical or Biological Substances, Environmental-Pollution-Related Condition
Potential Risk for Bacterial Contamination in Ventilator Systems
Background: Few studies have investigated the difference of bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems.
- Trial name
- NCT03359148
- Testing
- Disposable ventilator system, Conventional reused ventilator system
- Volunteers
- 27 people
- Sponsor
- Chang Gung University
Congenital Funnel Chest
Metal Contamination After Minimally Invasive Repair of Pectus Excavatum (MIRPE)
The purpose of this study is to determine whether there is a metal wear debris after minimally invasive repair of pectus excavatum and if there's a clinical relevance.
- Trial name
- NCT04751266
- Testing
- minimally invasive repair of pectus excavatum
- Volunteers
- 28 people
- Sponsor
- Dr. Caroline Fortmann
Septicemia
Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device When Collected Through Peripheral Intravenous Catheters
This is a randomized, open label study to evaluate the Initial Specimen Diversion Device (ISDD) in reducing the contamination rate in blood culture analysis.
- Trial name
- NCT02093494
- Testing
- Initial Specimen Diversion Device (ISDD), Lab standard practice (LSP), Peripheral Intravenous Catheters (PIVC)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Magnolia Medical Technologies, Inc.
Sinusitis
Comparison of Nasal Saline Irrigation Bottle Contamination Between Two Solutions
Rhinosinusitis is one of the most prevalent diseases within the United States and leads to decreased quality of life for patients suffering from this condition.
- Trial name
- NCT02413125
- Testing
- ChitoRhino irrigation solution, Normal saline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
C. Acnes, Arthroscopic Rotator Cuff Repair
Can Additional Preoperative Skin Cleaning on Face, Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?
The purpose of our study was to investigate whether preoperative skin cleaning on face, neck, and chest with chlorhexidine could reduce suture contamination of C. acnes in arthroscopic rotator cuff repair.
- Trial name
- NCT04483063
- Testing
- 2% chlorhexidine gluconate skin cleanser
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Cheng-Kung University Hospital
Surgical Glove, Total Knee Arthroplasty
Comparison of Surgical Glove Contamination During Total Knee Arthroplasty Procedure : a Randomized Controlled Trial
Total knee arthroplasty post-op surgical site infection rate about 0.5- 5% Pre-operative , perioperative and post-operative prevention are importance for reduce surgical site infection The prevention of surgical-site infections…
- Conditions
- Surgical Glove, Total Knee Arthroplasty, Contamination Rate
- Trial name
- NCT04308798
- Testing
- Surgical glove changing
- Where
- Thailand
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Incisional Hernia After Midline Laparotomy
Safety and Efficacy of Prophylactic Re-sorbable Biosynthetic Mesh Following Midline Laparotomy in Clean/Contaminated Field.
The aim of the present study is to analyse the feasibility, safety and IH rate using a prophylactic sublay biosynthetic BIO-A (GORE) mesh in order to prevent incisional hernia following midline laparotomy in clean-contaminated…
- Trial name
- Parthenope (NCT04471311)
- Testing
- Sub-lay mesh supported closure, BIO-A (GORE) mesh
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Orthodontics
Evaluation of the Contamination of Ligatures
This crossover, in-vivo study was carried out with 10 patients who have been started to be treated at Orthodontics Department. 3 elastomeric ligatures were examined in terms of microbiological and surface roughness.
- Trial name
- NCT04185987
- Testing
- Leone slide low friction elastomeric ligature, RMO tough - o energy elastomeric ligature, Dentsply sili tie elastomeric ligature
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- University of Gaziantep
Bacterial Contamination of Healthcare Worker Uniforms
Bacterial Contamination of Healthcare Worker Uniforms
Healthcare worker uniforms are frequently contaminated with bacteria known to cause infections in humans. These bacteria are acquired during the workday.
- Trial name
- NCT01537835
- Testing
- Antimicrobial Scrubs
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Respiratory Insufficiency
RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
Aerosol delivery during mechanical ventilation has long been a long debated topic. As evidence-based knowledge about the delivery of aerosol to the lungs of mechanically ventilated patients increases, one piece of the puzzle has…
- Trial name
- NCT02056119
- Testing
- Vibrating Mesh Nebulizer Arm, Jet Nebulizer Arm
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rush University Medical Center
Intraoperative Complications
The Effect of Hair Removal on Intraoperative Contamination
A prospective, non-blinded, randomized controlled trial with the purpose of investigating, whether preoperative electrical clipping of body hair affects the risk of intraoperative contamination.
- Trial name
- NCT04256928
- Testing
- Preoperative electrical clipping
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Herlev and Gentofte Hospital
Efficacy of Hand Hygiene Protocols
Efficacy of Alcohol Hand-rubbing Covering All Hand Surfaces in Reducing Bacterial Hand Contamination of Healthcare Staff
This is a randomized controlled trial comparing the effectiveness of three hand hygiene protocols, during routine inpatient clinical care: Protocol 1: handrubbing with alcohol covering all hand surfaces in no particular order…
- Trial name
- B/07/310 (NCT01337856)
- Testing
- Hand hygiene protocol
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Surgical Site Infection
Study of Chlorhexidine Gluconate as a Preoperative Antisepsis
The purpose of this study is to determine which drug (chlorhexidine gluconate vs. povidone iodine) as a preoperative antisepsis in clean-contaminated abdominal surgery (liver, hepatobiliary, small or large bowel, stomach) is…
- Trial name
- CHG (NCT01495117)
- Testing
- Povidone-Iodine, Chlorhexidine gluconate
- Where
- South Korea
- Volunteers
- 534 people
- Sponsor
- Seung Duk Lee
Hospital Acquired Infection
The Impact of Bedside Wipes in Multi-patient Rooms: a Prospective, Crossover Trial Evaluating Infections and Survival
Multidrug resistant organisms (MDRO) are prevalent in hospitals and are associated with hospital-acquired infections (HAI). High-touch surfaces serve as reservoirs and fomites for MDRO transmission.
- Trial name
- NCT05522725
- Testing
- Single-use wipes installed at the bedside
- Where
- Israel
- Volunteers
- 7,725 people
- Sponsor
- Assaf-Harofeh Medical Center
Preventing Blood Culture Contamination
Reducing Blood Culture Contamination:
Bloodstream infections cause significant morbidity and mortality and their prompt identification is an essential part of modern medicine. False positive results in blood cultures are primarily due to contaminants.
- Trial name
- NCT02754791
- Testing
- Steripath, Soluprep
- Volunteers
- 1,500 people
- Sponsor
- Shaare Zedek Medical Center
Airway Aspiration, Cardiopulmonary Arrest
Benefit of the SALAD Technique on CPR Quality During Intubation in Contaminated Airway
Management of airways in contaminated environments can compromise the quality of cardiopulmonary resuscitation (CPR). This study examined the effectiveness of SALAD (Suction Assisted Laryngoscopy Airway Decontamination) compared…
- Trial name
- NCT06427655
- Testing
- SALAD intubation
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital