Clinical trials: Contamination
Lung Cancer (Locally Advanced or Metastatic)
Evaluation of Endobronchial Ultrasound Needle Cleaning Techniques and Their Impact on Specimen Contamination
Endobronchial ultrasound (EBUS) bronchoscopy is commonly used to sample lymph nodes in patients with suspected or known lung cancer to determine the stage of the disease.
- Trial name
- EBUS (NCT07461662)
- Testing
- Purge cleaning
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Mississippi Medical Center
Surgical Site Infection
Efficacy of NPWT in Reducing the Incidence of Wound Infection After Pancreatic Surgery
A disposable negative wound pressure device will be compared to standard sterile wound dressing in reducing the rate of wound infection after clean-contaminated surgical procedures on biliary tract and pancreas in patients at…
- Trial name
- NCT03700086
- Testing
- Disposable negative wound pressure device (PICO), OPsite post-op visible standard sterile dressing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Dental Caries
Two Years Survival Rate of Class II ART Restorations in Primary Molars Using Two Ways to Avoid Saliva Contamination
AIM: To evaluate influence of two methods to avoid saliva contamination on the survival rate of atraumatic restorations in primary molars.
- Trial name
- NCT01924611
- Testing
- Atraumatic Restorative Technique using cotton rolls, Atraumatic Restorative Technique
- Where
- Brazil
- Volunteers
- 232 people
- Sponsor
- Federal University of Paraíba
Hernia Repair With Compartment Syndrome
Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
This study examines the feasibility of using Flex HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrixin the repair of hernias.
- Trial name
- Flex HD (NCT01597128)
- Testing
- Flex HD, Strattice
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- John Roth
Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children
Plaque Removal in Children Using Charcoal and Nylon Toothbrushes
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush.
- Trial name
- NCT07563400
- Testing
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle, soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infection Viral
COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults - Impact of Variants (Dyn3CEA - Nosocor Phase 2)
Unlike other respiratory viruses such as influenza and RSV where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in the transmission of CoV2-CoRSA…
- Trial name
- NCT04924842
- Testing
- Review of medical file, Phone call interview
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Hospices Civils de Lyon
Cystic Fibrosis
Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI)
The purpose of this interventional Phase IV study was to explore the ease of use of TIP and prevalence of microbial contamination of the T-326 Inhaler compared with TIS and colistimethate administered via nebuliser for the…
- Trial name
- NCT01844778
- Testing
- Tobramycin Inhalation Powder, Tobramycin inhalation solution, Colistimethate
- Where
- 21 sites in Germany, Ireland and 3 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Cannabis
The Pharmacokinetics of a Hemp-Based Topical Product
This study will evaluate the pharmacokinetic effects of acute and chronic dosing of a hemp-based cannabidiol (CBD) topical lotion with low levels of delta-9-tetrahydrocannabinol (THC) in a sanitized and controlled environment.
- Trial name
- NCT07603518
- Testing
- CBD, THC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bacterial Contamination
The Effectiveness of Antimicrobial Breathing System on the Presence of Multidrug-resistant Organisms
The aim of this study is to investigates the effectiveness of antimicrobial breathing system on multidrug-resistant organisms (MDRO).
- Trial name
- NCT04927806
- Testing
- Silver Knight
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Fu Jen Catholic University
Stress Disorders, Post-Traumatic, Shame
Healthy Recovery After Trauma Study
Mental contamination-an internal experience of dirtiness evoked in the absence of physical contact with an external source-has been linked to the development and maintenance of posttraumatic stress disorder (PTSD) following…
- Conditions
- Stress Disorders, Post-Traumatic, Shame, Guilt, Sexual Assault and Rape
- Trial name
- HRT (NCT04585685)
- Testing
- Cognitive Processing Therapy, Self-Compassion Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Christal L Badour
Post-operative Infections
Reduction in IV Associated Contamination
The purpose of this study is to investigate whether implementing a novel syringe and IV stopcock cap system impregnated with alcohol will reduce IV catheter bacterial contamination and infections in patients.
- Trial name
- NCT01426217
- Testing
- Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Disease Transmission
Antiseptic Scrub Contamination and Transmission Trial
This study is a prospective, blinded, randomized, controlled trial (RCT) with a crossover design to determine if antiseptic-impregnated surgical scrubs decrease the burden of healthcare providers (HCP) clothing contamination…
- Trial name
- ASCOT (NCT02645214)
- Testing
- Non-antiseptic scrubs, Antiseptic scrubs
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Infection
Optimal Feeding Tube Dwell Time in VLBW Infants to Reduce Feeding Tube Contamination
The study team will determine whether a decreased feeding tube dwell time will reduce feeding tube contamination
- Trial name
- NCT03728608
- Testing
- Feeding tube dwell time of 48 hours, Feeding tube dwell time of 7 day
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- University of Florida
Severe Traumatic Brain Injury, Pancreatic Diseases
The Effect of Closed Suction System on the Incidence of Ventilator-associated Pneumonia.
The investigators are suggesting that closed suction systems may reduce the risk of the ventilator - associated pneumoniae (VAP) and the contamination of the closest unanimated surfaces. In 2011 David et al.
- Conditions
- Severe Traumatic Brain Injury, Pancreatic Diseases, Trauma Injury, Seizures
- Trial name
- CSS-VAP (NCT04323150)
- Testing
- Closed suction systems, Conventional suction system
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Surgical Wound Infection, Surgical Site Infection
Assessing Parenteral Antibiotics Versus Single-time Intra-operative Intra-dermal Antibiotic Administration for Prevention of SSI
The purpose of the study is to study the incidence of surgical site infection when patients are given local versus parenteral antibiotics
- Trial name
- NCT04975945
- Testing
- Ceftriaxone Sodium
- Where
- India
- Sponsor
- The Grant Medical College & Sir J.J. Group of Hospitals
to Evaluate Antimicrobial Effect of Eco-friendly Toothbrush
Evaluation of Bacterial Contamination and Antimicrobial Efficacy on Charcoal-Infused vs, Standard Nylon Toothbrush Bristles.
This study compares two types of toothbrushes to see which one stays cleaner after use. Researchers want to know if toothbrushes with charcoal-infused bristles have fewer bacteria than standard toothbrushes with nylon bristles.
- Trial name
- NCT07365748
- Testing
- Eco-friendly toothbrush for children, nylon bristles toothbrush in children, Nylon bristles toothbrush in adults
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MTI University
Potentially Contaminated Hernia Repair, Potentially Contaminated Abdominal Wall Reconstruction
Study Comparing Tutomesh® Repair to Conventional Surgical Techniques in Potentially Contaminated Hernia Repair and Abdominal Wall Reconstruction
This is a multicentric prospective randomized study comparing technique of tension-free repair with placement of a bovine pericardium bioprosthesis (Tutopatch® and Tutomesh®) to current conventional surgical techniques in…
- Trial name
- Tutomesh (NCT01073072)
- Testing
- Conventional technique, Technique Tutomesh®
- Where
- 19 sites in France
- Volunteers
- 134 people
- Sponsor
- Centre Hospitalier Régional Universitaire Montpellier
Healthy
PCR-Based Detection of Bacterial Agents in Platelet Concentrates and Whole Blood
Using methods of molecular biology bacteria can be detected in blood. In comparison to conventional blood cultures "bacterial DNA" is isolated using a new sample preparation system in platelet apheresis concentrates and in the…
- Trial name
- NCT00482339
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Jena
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Urinary Tract Infections
Clean Catch Urine Feasibility and Contamination Rate Compared to Bladder Catheterization Urine in Pre-Continent Children
Introduction: Urinary tract infections (UTIs) are a common source of infection in children, accounting for a significant proportion of visits every year.
- Trial name
- NCT06265142
- Testing
- Bladder catheterization, clean catch urine via bladder massage technique
- Volunteers
- 80 people
- Sponsor
- Oman Medical Speciality Board